Low profile non-symmetrical stent

• US 8,740,966 B2
• Filed: 11/19/2009
• Issued: 06/03/2014
• Est. Priority Date: 12/26/2007
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Inventors: Brocker, David, Dierking, William K., Leewood, Alan R., Chuter, Timothy A. M., Roeder, Blayne A., Charlebois, Steven J., Swift, Richard A., Gopalakrishnamurthy, Sharath, Huser, Matthew, Kratzberg, Jarin, Oehlenschlaeger, Bent, Rasmussen, Erik E., Jensen, Kim Mgelvang
• Primary Examiner(s): Iwamaye, Andrew
• Assistant Examiner(s): Coburn, Leslie
• Application Number:
  US12/622,351
• Publication Number:
  US 20100161026A1
• Time in Patent Office: 1,657 Days
• Field of Search: 623/1.15, 623/1.13, 623/1.3, 623/1.31
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 conical

Abstract

A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.

Claims

1. A stent comprising:

a plurality of narrower distal apices defining a first generally circular outer profile, at least one of said distal apices comprising

first and second generally straight portions and

a first curved portion disposed between the first and second generally straight portions and comprising a first radius of curvature; and

a plurality of broader proximal apices defining a second generally circular outer profile, at least one of said proximal apices comprising

third and fourth generally straight portions and

a second curved portion disposed between the third and fourth generally straight portions and comprising a second radius of curvature that is greater than the first radius of curvature,

where an outer diameter defined by the broader apices of the second generally circular outer profile is greater than an outer diameter defined by the narrower apices of the first generally circular outer profile;

where at least one of the first and second generally straight portions is continuous with at least one of the third and fourth generally straight portions,

where the first radius of curvature is from about 0.5 mm to about 1.5 mm,

where the second radius of curvature is from about 4 mm to about 9 mm, and

where a ratio of the first radius of curvature to the second radius of curvature is about 1;

2.6 to about 1;

18, and

where the stent comprises at least one uncovered region.

2. The stent of claim 1 where the plurality of narrower distal apices and the plurality of broader proximal apices comprise outer surfaces of which define a cylinder having a generally consistent circumference.

3. The stent of claim 1 where the first radius of curvature is about 1 mm, and the second radius of curvature is about 6 mm.

4. The stent of claim 1 where each of the proximal apices are circumferentially offset from the distal apices.

5. The stent of claim 1 where the plurality of narrower distal apices and the plurality of broader proximal apices comprise outer surfaces of which define a frustum of a cone.

6. The stent of claim 5, further comprising a graft, where at least one distal apex of the stent is attached to the graft using one or more sutures.

7. The stent of claim 1 where at least one of the proximal apices comprises first and second fillets disposed a distance from the second curved portion, the first fillet comprising a first fillet radius of curvature and the second fillet comprising a second fillet radius of curvature.

8. The stent of claim 7 where the first fillet radius of curvature and the second fillet radius of curvature each have a radius of curvature of about 1 mm, and the first curved portion has a radius of curvature of about 0.5 mm.

9. The stent of claim 7 where the ratio of the first radius of curvature of the first curved portion to at least one of the first and second fillet radius of curvature is about 1:

1 to about 1;

10.

10. The stent of claim 7, further comprising a graft, where at least one distal apex of the stent is attached to the graft using one or more sutures.

11. The stent of claim 1,

where the stent includes a wire having the first curved portion, the second curved portion, and the first, second, third and fourth generally straight portions and generally defining a cylinder;

where the first radius of curvature is about 1 mm; and

the second radius of curvature is about 6 mm.

12. The stent of claim 1 where a ratio of the first radius of curvature to the second radius of curvature is about 1:

6.

13. A stent comprising:

a plurality of broader apices forming a first generally circular outer profile and a plurality of narrower apices forming a second generally circular outer profile connected with the broader apices by a plurality of generally straight portions;

where each broader apex comprises a first curved portion and each narrower apex comprises a second curved portion;

where the first curved portion and the second curved portion each comprises at least one radius of curvature, and the radius of curvature of at least one of the broader apices is greater than the radius of curvature of at least one of the narrower apices; and

where an outer diameter defined by the first generally circular outer profile is greater than an outer diameter defined by the second generally circular outer profile,

where the radius of curvature of the narrower apices is from about 0.5 mm to about 1.5 mm,

where the radius of curvature of the broader apices is from about 4 mm to about 9 mm, and

where a ratio of the radius of curvature of the narrower apices to the radius of curvature of the broader apices is about 1;

2.6 to about 1;

18, and

where the stent comprises at least one uncovered region.

14. The stent of claim 13 where an outer circumference around the broader apices is greater than an outer circumference around the narrower apices.

15. The stent of claim 13 further comprising a graft, where at least one narrower apex of the stent is attached to the graft using one or more sutures.

16. The stent of claim 15, further comprising at least one branch stent, at least one branch graft, or at least one branch stent-graft, a portion of which is at least disposed transversely through an inner radius of one of the plurality of broader apices.

17. The stent of claim 15, further comprising a second stent attached to the graft, where the second stent comprises plurality of proximal apices and a plurality of distal apices connected with the proximal apices by a plurality of generally straight portions;

where each proximal apex of the second stent comprises a first curved portion and each distal apex of the second stent comprises a second curved portion;

where the first curved portion of the second stent and the second curved portion of the second stent each comprises at least one radius of curvature, and the radius of curvature of at least one of the distal apices of the second stent is greater than the radius of curvature of at least one of the proximal apices of the second stent.

18. The stent of claim 15, further comprising a bare stent attached to and extending distally from the graft.

19. The stent of claim 18, further comprising at least one stent attached to and providing columnar support for the graft.

20. The stent of claim 13 where a ratio of the radius of curvature of the narrower apices to the radius of curvature of the broader apices is about 1:

6.

21. A stent graft comprising:

a tube having first and second ends and comprising a graft material;

at least one stent, including

a plurality of narrow apices defining a first generally circular outer profile; and

a plurality of broad apices defining a second generally circular outer profile;

where adjacent broad and narrow apices alternate and are separated by generally straight intermediate portions;

where at least some of the plurality of narrow apices are attached directly to the first end of the tube,

where the radius of curvature of the narrow apices is from about 0.5 mm to about 1.5 mm,

where the radius of curvature of the broad apices is from about 4 mm to about 9mm, and

where a ratio of the radius of curvature of the narrow apices to the radius of curvature of the broad apices is about 1;

2.6 to about 1;

18, and

where the stent comprises at least one uncovered region.

22. The stent graft of claim 21, where an outer diameter defined by the second generally circular outer profile is greater than an outer diameter defined by the first generally circular outer profile.

23. The stent graft of claim 21, where the at least one stent comprises a second stent, where at least some of a plurality of narrow apices of the second stent are attached directly to the second end of the tube.

24. The stent of claim 21 where a ratio of the radius of curvature of the narrow apices to the radius of curvature of the broad apices is about 1:

6.