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Disposable cartridge for fluid analysis

  • US 8,741,234 B2
  • Filed: 12/27/2011
  • Issued: 06/03/2014
  • Est. Priority Date: 12/27/2011
  • Status: Active Grant
First Claim
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1. A disposable blood analysis cartridge for analyzing a blood sample, comprising:

  • a microfluidics circuit having an optical scattering fluid measurement channel and an optical absorbance measurement channel;

    the optical absorbance measurement channel including;

    a sample introduction region;

    a plasma separation region in fluid communication with the sample introduction region;

    a sub channel in fluid communication with the plasma separation region, the sub channel configured to receive a plasma portion of a blood sample that is introduced into the sample introduction region, after the blood sample has passed through the plasma separation region;

    the sub channel having a cuvette, and a gas permeable membrane downstream of the cuvette;

    a vacuum port situated downstream of the gas permeable membrane; and

    wherein a negative pressure applied to the vacuum port may draw the plasma portion of the blood sample from the plasma separation region, into the sub channel and to the cuvette, so that an optical absorbance of the plasma portion of the blood sample can be measured at the cuvette.

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