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Highly porous, recognitive polymer systems

  • US 8,741,316 B2
  • Filed: 12/04/2008
  • Issued: 06/03/2014
  • Est. Priority Date: 03/12/2007
  • Status: Active Grant
First Claim
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1. A composition comprising:

  • one or more active agents disposed in a recognitive polymeric matrix comprisinga methacrylic acid polymerized to form a polymeric hydrogel matrix;

    a porosigen distributed in the polymeric hydrogel matrix wherein the porosigen comprises sodium chloride in a final weight percent of between 20 and 90 percent of the composition;

    a recognitive molecule disposed in the polymeric hydrogel matrix and associated with the one or more active agents to form a porous recognitive polymeric hydrogel,wherein the recognitive molecule recognizes a recognized agent and the porous recognitive polymeric hydrogel dissociates in the presence of the recognized agent to release the one or more active agents, wherein the recognitive agent comprises D-glucose and the one or more active agents comprising insulin.

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