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Subcutaneous glucose electrode

  • US 8,741,590 B2
  • Filed: 04/03/2007
  • Issued: 06/03/2014
  • Est. Priority Date: 03/04/1991
  • Status: Expired due to Fees
First Claim
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1. An electrochemical biosensor having a layered structure, comprising:

  • a supporting layer having at least one surface;

    an electrode in contact with the at least one surface of the supporting layer, the electrode including carbon;

    a sensing layer comprising an analyte-responsive enzyme;

    a biocompatible layer disposed over the sensing layer of the electrode; and

    an interferant eliminating layer comprising a redox enzyme;

    wherein at least a portion of the sensing layer and the biocompatible layer allow diffusion of an analyte therethrough;

    wherein the electrode is connectable with a device; and

    furtherwherein the electrode is a working electrode, the working electrode comprises the analyte-responsive enzyme and a mediator, at least one of the analyte-responsive enzyme and the mediator is chemically bonded to a polymer disposed on the working electrode, and at least one of the analyte-responsive enzyme and the mediator is crosslinked with the polymer.

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