Devices and methods for treatment of heart failure and associated conditions
First Claim
1. A system, comprising:
- a means for measuring blood pressure of a patient;
a means for measuring heart rate of the patient;
an implantable baroreflex activation device including an electrode, the implantable baroreflex activation device configured to be implanted such that the electrode is in contact with a blood vessel of the patient; and
a control system coupled to the means for measuring blood pressure, the means for measuring heart rate, and the implantable baroreflex activation device, the control system including predetermined ranges for each of blood pressure, heart rate and blood vessel properties, the control system programmed to automatically;
determine an impedance of the blood vessel with the electrode;
determine one or more blood vessel properties based on the impedance of the blood vessel;
determine a blood pressure based on the means for measuring blood pressure;
determine a heart rate based on the means for measuring heart rate; and
activate, deactivate or otherwise modulate the baroreflex activation device to deliver a first baroreflex therapy in response to each of the blood pressure, the heart rate and the blood vessel properties being within the respective predetermined ranges, and deliver a second baroreflex therapy in response to one or more of the blood pressure, the heart rate and the blood vessel properties being outside the respective predetermined ranges.
2 Assignments
0 Petitions
Accused Products
Abstract
Devices and methods for use of identification, treatment and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including a plurality of electrodes, determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, generating at least one signal representative of a pressure waveform based on the impedance, activating, deactivating or otherwise modulating the baroreflex therapy system to deliver a therapy to treat heart failure based at least in part on the at least one signal representative of the pressure waveform.
55 Citations
12 Claims
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1. A system, comprising:
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a means for measuring blood pressure of a patient; a means for measuring heart rate of the patient; an implantable baroreflex activation device including an electrode, the implantable baroreflex activation device configured to be implanted such that the electrode is in contact with a blood vessel of the patient; and a control system coupled to the means for measuring blood pressure, the means for measuring heart rate, and the implantable baroreflex activation device, the control system including predetermined ranges for each of blood pressure, heart rate and blood vessel properties, the control system programmed to automatically; determine an impedance of the blood vessel with the electrode; determine one or more blood vessel properties based on the impedance of the blood vessel; determine a blood pressure based on the means for measuring blood pressure; determine a heart rate based on the means for measuring heart rate; and activate, deactivate or otherwise modulate the baroreflex activation device to deliver a first baroreflex therapy in response to each of the blood pressure, the heart rate and the blood vessel properties being within the respective predetermined ranges, and deliver a second baroreflex therapy in response to one or more of the blood pressure, the heart rate and the blood vessel properties being outside the respective predetermined ranges. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method, comprising:
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causing a blood pressure measuring means to be manufactured and made available to a user; causing a heart rate measuring means to be manufactured and made available to the user; causing an implantable baroreflex activation device to be manufactured and made available to a user, the implantable baroreflex activation device including an electrode, the implantable baroreflex activation device configured to be implanted such that the electrode is in contact with a blood vessel of the patient; and causing a control system to be manufactured and made available to the user, the control system coupled to the blood pressure measuring means, the heart rate measuring means and the implantable baroreflex activation device, the control system including predetermined ranges for each of blood pressure, heart rate and blood vessel properties, the control system programmed to automatically; determine an impedance of the blood vessel with the electrode over a time period of at least one cardiac cycle; determine one or more properties of the blood vessel properties based on the impedance; receive an indication of blood pressure from the blood pressure sensing means; receive an indication of heart rate from the heart rate sensing means; and activate, deactivate or otherwise modulate the baroreflex activation device to deliver a first baroreflex therapy in response to each of the blood pressure, the heart rate and the blood vessel properties being within the respective predetermined ranges, and deliver a second baroreflex therapy in response to one or more of the blood pressure, the heart rate and the blood vessel properties being outside the respective predetermined ranges. - View Dependent Claims (11, 12)
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Specification