Intraocular lens having extended depth of focus

• US 8,747,466 B2
• Filed: 08/23/2008
• Issued: 06/10/2014
• Est. Priority Date: 08/27/2007
• Status: Active Grant

• Current Assignee: Amo Groningen B.V (Johnson & Johnson)
• Original Assignee: Amo Groningen B.V (Johnson & Johnson)
• Inventors: Weeber, Hendrik A., Piers, Patricia Ann
• Primary Examiner(s): Willse, David H
• Assistant Examiner(s): SHIPMON, TIFFANY P
• Application Number:
  US12/197,249
• Publication Number:
  US 20090187242A1
• Time in Patent Office: 2,117 Days
• Field of Search: 623/6.24, 623/6.27, 623/6.3
• US Class Current: 623/6.28
• CPC Class Codes: A61F 2/1654 Diffractive lenses
• CPC Class Codes: A61F 2002/1699 Additional features not otherwise provided for
• CPC Class Codes: G02B 27/0075 with means for altering, e.g. increasing, the depth of field or depth of focus

Abstract

An intraocular lens is disclosed, which includes a diffractive element with a relatively low add power. The add power may be less than about 2 Diopters, may be less than about 1 Diopter, or may be in the ranges of 0.5 to 2.5 Diopters, or 1.0 to 2.0 Diopters, or 1.5 to 2.0 Diopters, or 1.0 to 1.5 Diopters. The low-add-power diffractive element increases the depth of the focus of the intraocular lens, for example, compared to a similarly shaped intraocular lens without the diffractive element. In one embodiment, the depth of focus is defined in terms of a threshold MTF value at a particular spatial frequency. The threshold may be an absolute threshold, such as 0.10, 0.15, 0.17, 0.20, 0.25 or 0.30, or may be a relative threshold, such as a particular percentage of the peak value. The spatial frequency may be 25 line pairs per mm, 50 line pairs per mm, 100 line pairs per mm, or any suitable value.

Claims

1. An intraocular lens, comprising:

an optic including a first surface having a first shape and an opposing second surface having a second shape, the first and second shapes providing a refractive power;

a diffractive pattern imposed on at least one of the first shape and the second shape with a concentric central zone having a center and a plurality of concentric zones surrounding the central zone wherein the central zone and the plurality of concentric zones are each comprised of an edge with a step discontinuity at the edge having a step height between about 1 micron and 3.3 microns, wherein the central zone is configured such that the edge of the central zone is 360°

out of phase with the center of the central zone; and

wherein

the first and second surfaces provide a base power and an add power that is between 0.5 Diopter and 1.5 Diopter so that the intraocular lens has a depth of focus that exceeds that of any single focus of a similar spherical lens having an optical power equal to the base power of the intraocular lens.

2. The intraocular lens of claim 1, wherein the central zone radius is equal to or about 1.05 mm.

3. The intraocular lens of claim 1, wherein the add power is equal to about one Diopter.

4. The intraocular lens of claim 1, wherein the diffractive pattern has a first diffracted order providing a first diffractive power, the base power being determined at least in part by the refractive power, the add power being determined at least in part by the first diffractive power.

5. The intraocular lens of claim 1, wherein the diffractive pattern has a nth diffracted order providing a first diffractive power and a (n+1)th diffracted order providing a second diffractive power, the base power being determined at least in part by the refractive power and the first diffractive power, the add power being determined at least in part by the difference between the second diffractive power and the first diffractive power.

6. The intraocular lens of claim 1, wherein at least one of the first and second shapes has an aspheric component.

7. The intraocular lens of claim 1, wherein the diffractive pattern has a plus first diffracted order providing a first diffractive power and a minus first diffracted order providing a second diffractive power, the base power being determined at least in part by the refractive power and the first diffractive power, the add power being determined at least in part by the difference between the second diffractive power and the first diffractive power.

8. The intraocular lens of claim 1, wherein the base power and the add power are formed from adjacent diffracted orders, respectively, from the diffractive pattern.

9. The intraocular lens of claim 1, wherein the base power and the add power result in a first focus and a second focus that have equal intensities.

10. The intraocular lens of claim 1, further comprising first and second foci formed from different diffracted orders.

11. An intraocular lens, comprising:

an optic including a first surface having a first shape and an opposing second surface having a second shape, the first and second shapes providing a refractive power;

a diffractive pattern imposed on at least one of the first shape and the second shape with a concentric central zone having a center and a plurality of concentric zones surrounding the central zone wherein the central zone and the plurality of concentric zones are each comprised of an edge with a step discontinuity at the having a step height between about 1 micron and 3.0 microns, wherein the central zone is configured such that the edge of the central zone is 360°

out of phase with the center of the central zone; and

wherein the first and second surfaces provide a base power and an add power that is between 0.5 Diopter and 1.5 Diopter such that when the intraocular lens is optically described by a model lens, and the model lens is included in an intraocular lens plane of an eye model including a model cornea, a design wavelength of 550 nm, and a pupil radius of 1.5 mm, the eye model has an extended depth of focus characterized by a modulation transfer function that exceeds 0.17, at a spatial frequency of 50 line pairs per millimeter, over a range of at least about 1.7 Diopters.

12. The intraocular lens of claim 11, wherein the eye model is a Liou-Brennan eye model or a Norrby Modified ISO eye model.

13. The intraocular lens of claim 11, wherein the modulation transfer function of the eye model exceeds about 0.20, at a spatial frequency of 50 line pairs per millimeter, over a range of at least about 1.9 Diopters.

14. An intraocular lens, comprising:

an optic comprising a first surface having a first shape and an opposing second surface having a second shape, the first and second shapes providing a refractive power;

a diffractive pattern imposed on at least one of the first shape and the second shape with a concentric central zone having a center and a plurality of concentric zones surrounding the central zone wherein the central zone and the plurality of concentric zones are each comprised of an edge with a step discontinuity at the edge having a step height between about 1 micron and 3.0 microns, wherein the central zone is configured such that the edge of the central zone is 360°

out of phase with the center of the central zone; and

wherein the first and second surfaces provide a base power and an add power that is between 0.5 Diopter and 1.5 Diopter such that when the optic is placed in an intraocular lens plane of a physical eye model including a model cornea, a design wavelength of 550 nm, and a pupil radius of 1.5 mm, the eye model has an extended depth of focus characterized by a modulation transfer function that exceeds 0.17, at a spatial frequency of 50 line pairs per millimeter, over a range of at least about 1.7 Diopters.

15. The intraocular lens of claim 14, wherein the eye model is a Norrby Modified ISO eye model.

16. An intraocular lens, comprising:

an optic including a first surface having a first shape and an opposing second surface having a second shape, the first and second shapes providing a refractive power;

a diffractive pattern imposed on the first shape or the second shape with a concentric central zone having a center and a plurality of concentric zones surrounding the central zone wherein the central zone and the plurality of concentric zones are each comprised of an edge with a step discontinuity at the edge having a step height between about 1 micron and 3.0 microns, wherein the central zone is configured such that the edge of the central zone is 360°

out of phase with the center of the central zone such that the intraocular lens has an extended depth of focus characterized by a depth of focus that is at least about 30% greater than that of a reference lens without a diffractive pattern, the reference lens having a refractive power that is equal to the base power of the intraocular lens.

17. The intraocular lens of claim 16, wherein the light source is a polychromatic light source.

18. The intraocular lens of claim 17, wherein the polychromatic light source is described by a Liou-Brennan eye model.

19. The intraocular lens of claim 16, wherein the light source is at a predetermined wavelength and the intraocular lens has a depth of focus, when illuminated at the predetermined wavelength, that is at least about 50% greater than that of the intraocular reference lens.

20. The intraocular lens of claim 19, wherein the predetermined wavelength is about 546 nm.

21. The intraocular lens of claim 16, wherein, at a spatial frequency of about 50 line pairs per millimeter, the modulation transfer function of the lens exceeds 0.17 over a depth of focus that is greater than the depth of focus for the reference intraocular lens by at least about 0.5 Diopters.

22. The intraocular lens of claim 16, wherein the intraocular lens is optically described by a model lens, such that when the model lens is included in an intraocular lens plane of an eye model including a model cornea, the modulation transfer function of the eye model exceeds about 0.17, at a spatial frequency of about 50 line pairs per millimeter, over a focal range of at least about 1.7 Diopters.