Methods for making braid-ball occlusion devices

• US 8,747,597 B2
• Filed: 03/15/2011
• Issued: 06/10/2014
• Est. Priority Date: 04/21/2008
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Rosqueta, Arturo S., Becking, Frank P.
• Primary Examiner(s): Orlando, Michael
• Assistant Examiner(s): DULKO, MARTA S
• Application Number:
  US13/048,648
• Publication Number:
  US 20110265943A1
• Time in Patent Office: 1,183 Days
• Field of Search: 156/227, 606/200
• US Class Current: 156/227
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12118 for positioning in conjunction with a stent
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/00526 Methods of manufacturing
• CPC Class Codes: A61B 2017/00862 elastic or resilient
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12068 detachable by heat
• CPC Class Codes: A61B 2018/00416 Treatment of aneurisms
• CPC Class Codes: A61B 2090/3966 Radiopaque markers visible in an X-ray image
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104
• CPC Class Codes: Y10T 156/1051 by folding

Abstract

Embolic implants, delivery systems and methods of manufacture and delivery are disclosed. The devices can be used for aneurysm treatment and/or parent vessel occlusion. Implant designs offer low profile compressibility for delivery to neurovasculature, while maintaining other necessary features such as density for occlusion purposes and desirable radial strength characteristics.

Claims

1. A method of making an embolic device, the method comprising:

collapsing a midsection of a tubular braid to a substantially closed configuration using a tie;

inverting a first tubular section of the tubular braid over the tie at the midsection to produce dual layers in the braid such that the braid has a tubular configuration with a closed end at the midsection and an open end opposite the midsection;

while holding the midsection substantially closed, inserting a form into the open end to position the dual layers of the braid around the form;

setting a device body shape; and

removing the tie and the form from the braid, the form being removed in one piece.

2. The method of claim 1, wherein the form is removed through the open end of the tubular braid in a direction away from the midsection.

3. The method of claim 1, wherein the dual layers are set into a compressed profile prior to setting the device body shape.

4. The method of claim 1, wherein the dual layers are set into a compressed profile while setting the device body shape.

5. The method of claim 1, further comprising advancing a band past the braid ends to a hub location.

6. The method of claim 5, further comprising trimming off a length of the braid including the braid ends adjacent the band.

7. The method of claim 5, further comprising wicking adhesive through the braid under to the band to secure the band and braid together.

8. The method of claim 7, wherein a non-stick mandrel defines an inner lumen within the braid when wicking the adhesive.

9. The method of claim 5, further comprising wicking adhesive away from the braid outside the band along the braid forming the embolic device.

10. The method of claim 1, wherein the tie comprises a suture and the collapsing comprises tying the suture around the midsection onto a mandrel.

11. The method of claim 1, wherein the form is substantially spherical.

12. The method of claim 1, wherein the removing the tie comprises burning away the tie during heatsetting.

13. The method of claim 1, wherein the midsection is offset from ends of the braid such that an end of the first tubular section extends longitudinally beyond an end of the braid underlying the first tubular section when the first tubular section is inverted over the braid.

14. A method of making an embolic device, the method comprising:

constraining a midsection of a tubular braid in a substantially closed configuration;

inverting a first tubular section of the tubular braid over the midsection to produce a dual layer tubular section having a closed end, at the midsection and an open end opposite the closed end;

inserting a form within the dual layer section through the open end such that the form is positioned axially between the folded edge and the open end of the folded section; and

setting a device body shape based on the form; and

after setting the device body shape, removing the form in one piece from the braid.

15. The method of claim 14, wherein the constraining comprises crimping the midsection.

16. The method of claim 14, wherein the constraining comprises binding the midsection using a tie.

17. The method of claim 16, wherein the tie comprises a suture and constraining comprises tying the suture around the midsection onto a mandrel.

18. The method of claim 14, wherein the form is substantially spherical.

19. The method of claim 14, further comprising positioning the braid and the form between compression forms prior to setting.

20. The method of claim 14, further comprising removing the tie.