Cell population enriched for endoderm cells
First Claim
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1. An isolated cell population enriched for endoderm cells derived from mammalian embryoid bodies (EB) cultured in activin at a concentration of about 30 to about 100 ng/ml of activin, wherein the cell population is enriched for endoderm cells that express Sox-17, Hex-1, and HNF3β
- and do not express GATA1 or PAX6.
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Abstract
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy.
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3 Claims
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1. An isolated cell population enriched for endoderm cells derived from mammalian embryoid bodies (EB) cultured in activin at a concentration of about 30 to about 100 ng/ml of activin, wherein the cell population is enriched for endoderm cells that express Sox-17, Hex-1, and HNF3β
- and do not express GATA1 or PAX6.
- View Dependent Claims (2, 3)
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