Conductive mesh for neurostimulation

• US 8,751,003 B2
• Filed: 08/02/2006
• Issued: 06/10/2014
• Est. Priority Date: 02/11/2004
• Status: Active Grant

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: Ethicon Incorporated (Johnson & Johnson)
• Inventors: DiUbaldi, Anthony, Tracey, Michael R.
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): GHAND, JENNIFER LEIGH-STEWAR
• Application Number:
  US11/497,861
• Publication Number:
  US 20070185541A1
• Time in Patent Office: 2,869 Days
• Field of Search: 607/41
• US Class Current: 607/41
• CPC Class Codes: A61F 2/0045 Support slings
• CPC Class Codes: A61N 1/0512 Anal electrodes
• CPC Class Codes: A61N 1/0514 Electrodes for the urinary tract
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36003 of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36071 Pain

Abstract

A medial treatment device for treating at least first and second medical conditions is provided, as well as a method for using the same. The medical treatment device includes a stimulation device for treating the first medical condition with electrical stimulation, and an implantable mesh adapted for implantation within the patient to treat the second medical condition. The implantable mesh has a plurality of incorporated electrically conductive elements adapted to conduct electrical stimulation from the stimulation device to a position closer to a predetermined body part the stimulation of which at least partially treats the first medical condition.

Claims

1. A medical treatment device for treating at least first and second different medical conditions of a patient, comprising:

a neurostimulation device for stimulating a predetermined nerve to thereby treat first neurologically based condition of the patient, the neurostimulation device further comprising a first waveform generator adapted to generate a first waveform having a frequency capable of stimulating the predetermined nerve of the patient, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the patient, wherein the frequency of said carrier waveform is itself incapable of electrically stimulating the predetermined nerve, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the patient, and adapted to apply the modulated waveform thereto; and

biocompatible, implantable mesh adapted for implantation within tissue of the patient to mechanically treat the second medical condition of the patient, wherein the implantable mesh has a plurality of incorporated electrically conductive elements adapted to, when implanted, electrically conduct the modulate waveform that is applied to the skin through the body tissue within which it is implanted to a position within the body that is closer to the predetermined nerve than the electrode, and wherein the implantable mesh is adapted to support an internal organ or body part, and has a pore size adapted to promote tissue ingrowth when implanted,

wherein the modulated waveform maintains amplitude and frequency information of the first and carrier waveforms.

2. The device according to claim 1, wherein the plurality of electrically conductive elements are a plurality of electrically conductive fibers.

3. The device according to claim 2, wherein the implantable mesh is a knitted or woven mesh having the conductive fibers at least partially interwoven therein.

4. The device according to claim 2, wherein the implantable mesh is a knitted or woven mesh having the conductive fibers coupled thereto.

5. The device according to claim 2, wherein the conductive fibers further comprise a non-conductive core material at least partially coated with a conductive metal or conductive polymer.

6. The device according to claim 1 wherein the plurality of electrically conductive elements are separate elements coupled to the mesh at predetermined, discrete locations.

7. The device according to claim 1, wherein the plurality of electrically conductive elements are formed by coating the mesh with a conductive material at predetermined, discrete locations.

8. The device according to claim 1, Wherein the first and second waveform generators and the electrode are positioned within a patch device having an adhesive thereon for securing the patch to the skin.

9. The device according to claim 8, wherein the predetermined nerve is the pudendal nerve, and the patch is positioned substantially at the abdominal or sacral region of the mammal'"'"'s body.

10. The device according to claim 9, wherein the implantable mesh is a urethral sling for treating female urinary incontinence.

11. The device according, to claim 10, wherein the first waveform has a frequency substantially within the range of 10-40 Hz.

12. The medical treatment device according to claim 11, wherein the carrier waveform has a frequency substantially within the range of 10-400 kHz.

13. The device according to claim 1, wherein the mesh is a hernia repair mesh.

14. A method for treating at least first and second different medical conditions of a patient comprising:

generating a first waveform haying a frequency capable of stimulating a predetermined nerve of the patient to treat a first neurologically based condition of the patient;

generating a carrier waveform haying a frequency capable of passing through tissue of the patient, wherein the carrier waveform is itself incapable of electrically stimulating the predetermined nerve;

modulating said first waveform with the carrier waveform to produce a modulated signal adapted to stimulate a predetermined nerve to thereby treat a first neurologically based medical condition;

applying the modulated signal to the patient'"'"'s skin; and

implanting a biocompatible mesh within the patient'"'"'s body so as to support an internal organ or body part to thereby treat said second medical condition, the implantable mesh having a plurality of incorporated conductive elements to conduct the modulated signal that is applied to the skin through the body tissue within which it is implanted to a location within the patient'"'"'s body that is closer to the predetermined nerve than the electrode, and having pore size adapted to promote tissue ingrowth,

wherein the modulated signal maintains amplitude and frequency information of the first and carrier waveforms.

15. The method according to claim 14, wherein the plurality of conductive elements are a plurality of conductive fibers.

16. The method according to claim 15, wherein the plurality of conductive fibers extend substantially along a length of the mesh.

17. The method according to claim 15, wherein the plurality of conductive fibers are coupled with the mesh.

18. The method according to claim 14, wherein the plurality of conductive elements are separate elements secured to the mesh at a plurality of predetermined, discrete locations.

19. The method according to claim 14, wherein the plurality of conductive elements are formed by coating the mesh with a conductive material at a plurality of predetermined, discrete locations.

20. The method according to claim 14, wherein the modulated signal is applied to the mammal'"'"'s skin in the abdominal or sacral regions of the mammal'"'"'s body.

21. The method according to claim 14, wherein the first waveform has a frequency substantially within the range of 10-40 Hz, and the carrier waveform has a frequency substantially within the range of 10-400 kHz.

22. The method according to claim 14, wherein the predetermined nerve is the pudendal nerve.

23. The method according to claim 14, wherein the implanted mesh is a suburethral sling for treating female urinary incontinence.

24. The method according to claim 14, wherein the implanted mesh is a hernia repair mesh.

25. The method according to claim 14, wherein the modulated signal represents a multiplication of the first and carrier waveforms.

26. A medical treatment device for treating at least first and second different medical conditions of a patient, comprising:

a neurostimulation device for stimulating a predetermined nerve to thereby treat first neurologically based condition of the patient, the neurostimulation device further comprising a first waveform generator adapted to generate a first waveform haying a frequency capable of stimulating the predetermined nerve of the patient, a second waveform generator adapted to generate a carrier waveform having a frequency capable of passing through tissue of the patient, wherein the frequency of said carrier waveform is itself incapable of electrically stimulating the predetermined nerve, a modulation device electrically coupled to the first and second waveform generators and adapted to modulate the first and carrier waveforms to create a modulated waveform, and an electrode electrically coupled to the modulation device and positioned substantially adjacent to skin of the patient, and adapted to apply the modulated waveform thereto; and

biocompatible, implantable mesh adapted for implantation within tissue of the patient to mechanically treat the second medical condition of the patient, wherein the implantable mesh has a plurality of incorporated electrically conductive elements adapted to, when implanted, electrically conduct the modulate waveform that is applied to the skin through the body tissue within which it is implanted to a position within the body that is closer to the predetermined nerve than the electrode, and wherein the implantable mesh is adapted to support an internal organ or body part, and has a pore size adapted to promote tissue ingrowth when imprinted,

wherein the modulated waveform represents a multiplication of the first and carrier waveforms.