Fluid transfer system and method

• US 8,753,290 B2
• Filed: 03/24/2010
• Issued: 06/17/2014
• Est. Priority Date: 03/27/2009
• Status: Active Grant

• Current Assignee: Intellectual Discovery Co., Ltd.
• Original Assignee: Intellectual Inspiration, LLC
• Inventors: Bloom, Daniel, Nelson, Nicholas A., Jensen, Morten J., Shea, Laurence R., Donlon, Ed, Taylor, Stuart, Vivolo, Joe
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US12/731,010
• Publication Number:
  US 20110077480A1
• Time in Patent Office: 1,546 Days
• Field of Search: 600/316, 600/573, 600/575, 600/584
• US Class Current: 600/584
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150221 Valves
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150236 Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/150793 Electrical or magnetic identification means
• CPC Class Codes: A61B 5/150809 by audible feedback
• CPC Class Codes: A61B 5/150824 by visual feedback
• CPC Class Codes: A61B 5/15087 short range, e.g. between console and disposable using implanted devices A61B5/150877
• CPC Class Codes: A61B 5/150946 Means for varying, regulating, indicating or limiting the speed or time of blood collection
• CPC Class Codes: A61B 5/150961 Means for the detection of the presence or absence of a module, a component or an abnormal condition; detection of leaks
• CPC Class Codes: A61B 5/150992 Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves tubing connectors and couplings A61M39/00
• CPC Class Codes: A61B 5/1535 comprising means for indicating vein or arterial entry A61B5/1545 takes precedence
• CPC Class Codes: A61B 5/155 Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals devices loaded with multiple lancets simultaneously A61B5/15146
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/6866 Extracorporeal blood circuits, e.g. dialysis circuits

Abstract

Devices and methods for automatic monitoring of fluid of a patient are disclosed, comprising a patient line, a transfer disk which receives the fluid and controllably transfers the fluid to test substrates, and a sensor disk which houses the test substrates. The sterile transfer disk may be configured to maintain the sterility of the patient sampling assembly while transferring samples to non-sterile components, such as the sensor disk.

Claims

1. A fluid sensor device, comprising:

a plurality of transfer reservoirs, each transfer reservoir comprising an optically transmissive material, an inlet opening, an outlet opening, and a cavity comprising a deformable wall and a light-reflecting structure; and

a plurality of alignment structures, wherein at least one alignment structure is associated with each transfer reservoir.

2. The fluid sensor device of claim 1, wherein the deformable walls of the plurality of transfer reservoirs are deformable membranes.

3. The fluid sensor device of claim 1, wherein the cavities of the plurality of transfer reservoirs further comprise a fixed wall.

4. The fluid sensor device of claim 1, wherein the plurality of transfer reservoirs are located in a circular transfer cartridge and wherein the inlet openings of the plurality of transfer reservoirs are located on the outer circumferential surface of the circular transfer cartridge.

5. The fluid sensor device of claim 1, further comprising a sensor cartridge interface.

6. The fluid sensor device of claim 5, wherein the sensor cartridge interface comprises an alignment structure and at least one locking structure.

7. The fluid sensor device of claim 6, wherein the sensor cartridge interface further comprises a plurality of sensor substrate access apertures.

8. The fluid sensor device of claim 6, further comprising a sensor cartridge comprising a transfer cartridge interface complementary to the sensor cartridge interface of the transfer cartridge.

9. The fluid sensor device of claim 8, wherein the sensor cartridge further comprises a plurality of test strips.

10. The fluid sensor device of claim 8, wherein the sensor cartridge further comprises a plurality of fluid sample receiving regions, a plurality sensor substrates and a plurality of sensor electrode contacts.

11. The fluid sensor device of claim 8, wherein the plurality of fluid sample receiving regions are oriented to correspond to the outlet openings of transfer reservoirs when the transfer cartridge and sensor cartridge are attached.