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Methods for administering small volume oral transmucosal dosage forms using a dispensing device

  • US 8,753,308 B2
  • Filed: 11/15/2012
  • Issued: 06/17/2014
  • Est. Priority Date: 01/06/2006
  • Status: Active Grant
First Claim
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1. An apparatus, comprising:

  • a delivery tip defining a non-linear delivery passage, a distal end portion of the delivery tip defining an exit port;

    a push rod, at least a portion of the push rod being movably disposed in the delivery passage, a distal end portion of the push rod being within the delivery passage when the push rod is in a first position, the distal end portion of the push rod configured to deliver a drug-containing tablet through the exit port when the push rod is moved from its first position to a second position;

    a shroud coupled to the distal end portion of the delivery tip, at least a portion of the shroud configured to be disposed within a mouth of a patient between a tongue and a sublingual membrane and to inhibit contact by at least one of the tongue or the sublingual membrane with the exit port, the shroud including a hydrophilic material; and

    a seal disposed about the exit port, the seal configured to prevent the ingress of moisture into the exit port, a portion of the seal defining a slit configured to permit passage of the tablet and the distal end portion of the push rod therethrough during delivery of the tablet, the portion of the seal configured to maintain a seal about at least one of the tablet or the push rod when the push rod is moved from its first position to its second position to deliver the tablet.

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