Methods and apparatus for producing and using lightly filtered photoplethysmograph signals

• US 8,755,854 B2
• Filed: 07/31/2009
• Issued: 06/17/2014
• Est. Priority Date: 07/31/2009
• Status: Active Grant

• Current Assignee: Nellcor Puritan Bennett Ireland
• Original Assignee: Nellcor Puritan Bennett Ireland
• Inventors: Addison, Paul Stanley, Watson, James
• Primary Examiner(s): Laballe, Clayton E
• Assistant Examiner(s): BUTLER, KEVIN C
• Application Number:
  US12/533,239
• Publication Number:
  US 20110028802A1
• Time in Patent Office: 1,782 Days
• Field of Search: 600/310, 600/323, 600/330, 600/504
• US Class Current: 600/310
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/726 using Wavelet transforms

Abstract

One or more physiological conditions of a patient can be observed by obtaining a photoplethysmograph (“PPG”) signal from the patient and by only lightly filtering that signal. The light filtering of the PPG may be such as to only remove (for example) high frequency noise from that signal, while leaving in the signal most or all frequency components that are due to physiological events in the patient. In this way, such physiological events can be observed via a visual display of the lightly filtered PPG signal and/or via other signal processing of the lightly filtered PPG signal to automatically extract certain physiological parameters or characteristics from that signal.

Claims

1. Apparatus for monitoring a physiological condition of a patient comprising:

photoplethysmograph (“

PPG”

) circuitry configured to obtain a PPG signal from the patient;

filter circuitry configured to lightly filter the PPG signal to produce a lightly filtered PPG signal; and

output circuitry configured to provide a visible display of a trace of the lightly filtered PPG signal, thereby making it possible for a clinician user of the apparatus to observe at least some patient physiological condition information contained in the lightly filtered PPG signal.

2. The apparatus defined in claim 1 wherein the filter circuitry comprises:

a low-pass filter configured to pass components of the PPG signal having frequencies less than a threshold frequency and for blocking components of the PPG signal having frequencies greater than the threshold frequency.

3. The apparatus defined in claim 2 wherein the threshold frequency is approximately 4 Hz.

4. The apparatus defined in claim 1 wherein the filter circuitry comprises:

a band-pass filter configured to pass components of the PPG signal having frequencies in a range between upper and lower threshold frequencies and for blocking components of the PPG signal having frequencies that are not in said range.

5. The apparatus defined in claim 4 wherein the upper threshold frequency is approximately 4 Hz.

6. The apparatus defined in claim 4 wherein the lower threshold frequency is approximately 0.005 Hz.

7. The apparatus defined in claim 1 wherein the filter circuitry has a frequency threshold at which the filter circuitry switches from passing frequency components of the PPG signal to blocking frequency components of the PPG signal, and wherein the frequency threshold is controllably variable.

8. The apparatus defined in claim 7 further comprising:

processing circuitry configured to analyze the lightly filtered PPG signal to produce a control signal for controlling the frequency threshold.

9. The apparatus defined in claim 1 wherein the output circuitry comprises:

processing circuitry configured to analyze the lightly filtered PPG signal to produce an output signal indicative of a physiological parameter extracted from the patient physiological condition information contained in the lightly filtered PPG signal.

10. The apparatus defined in claim 1 further comprising:

polysomnogram (“

PSG”

) circuitry configured to obtain a PSG signal from the patient; and

wherein the output circuitry additionally makes it possible for the clinician user to observe at least some additional patient physiological condition information contained in the PSG signal.

11. The apparatus defined in claim 10 wherein the PSG circuitry comprises:

SpO2 circuitry configured to measure saturation of the patient'"'"'s hemoglobin with oxygen.

12. The apparatus defined in claim 10 wherein the PSG circuitry comprises:

breathing airflow monitoring circuitry.

13. The apparatus defined in claim 1 further comprising:

circuitry configured to extract from the PPG signal a breathing effort signal indicative of effort the patient is expending in order to breathe.

14. The apparatus defined in claim 13 wherein the output circuitry additionally makes it possible for the clinician user to observe the breathing effort signal.

15. The apparatus defined in claim 13 wherein the circuitry configured to extract comprises:

circuitry configured to produce scalogram signals from the PPG signal; and

circuitry configured to produce the breathing effort signal from the scalogram signals.

16. The apparatus defined in claim 15 wherein the output circuitry additionally makes it possible for the clinician user to observe the scalogram signals.

17. The apparatus defined in claim 1 further comprising:

circuitry configured to produce scalogram signals from the PPG signal; and

wherein the output circuitry additionally makes it possible for the clinician user to observe the scalogram signals.

18. The apparatus defined in claim 1, wherein the filter circuitry is configured to pass most or all of the patient physiological information in the PPG signal while blocking high frequency noise.

19. The apparatus defined in claim 1, wherein the filter circuitry is configured to pass principal components of the patient'"'"'s pulse and lower frequency components including long-term baseline undulations of the PPG signal.

20. The apparatus defined in claim 1, wherein the filter circuitry is configured to pass low frequency baseline changes of the PPG signal that are due to vasodilation and vasoconstriction, wherein the output circuitry makes it possible for the clinician user of the apparatus to observe vasodilation and vasoconstriction information contained in the lightly filtered PPG signal.

21. A method of monitoring a physiological condition of a patient comprising:

obtaining a photoplethysmograph (“

PPG”

) signal from the patient;

lightly filtering the PPG signal to produce a lightly filtered PPG signal; and

visibly displaying a trace of the lightly filtered PPG signal so that a clinician user of the method can observe at least some patient physiological condition information that is contained in the lightly filtered PPG signal.

22. The method defined in claim 21 wherein the lightly filtering comprises:

band-pass filtering the PPG signal with a pass band in the range from about 4 Hz to about 0.005 Hz.