PFO closure device with flexible thrombogenic joint and improved dislodgement resistance

• US 8,758,403 B2
• Filed: 06/28/2011
• Issued: 06/24/2014
• Est. Priority Date: 12/19/2001
• Status: Active Grant

• Current Assignee: WL Gore and Associates Incorporated (W.L. Gore and Associates)
• Original Assignee: WL Gore and Associates Incorporated (W.L. Gore and Associates)
• Inventors: Chanduszko, Andrzej J.
• Primary Examiner(s): Bui, Vy Q
• Application Number:
  US13/171,162
• Publication Number:
  US 20120029560A1
• Time in Patent Office: 1,092 Days
• Field of Search: 606/213, 606/215, 606/216, 606/153, 606/155, 606/157, 606/200, 604/500, 604/107
• US Class Current: 606/215
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00575 for closure at remote site, e.g. closing atrial septum defects
• CPC Class Codes: A61B 2017/00592 Elastic or resilient implements
• CPC Class Codes: A61B 2017/00606 Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening

Abstract

The present invention provides devices for closing septal defects, such as a patent foramen ovale (PFO). The closure devices include a proximal anchor member, a distal anchor member, and at least one flexible center joint connecting the two anchor members. According to some embodiments, the proximal and/or distal anchor members may include a generally cylindrical member split along the central portion of its length to form an elongate oval. The proximal and/or distal anchor members may further include a tissue scaffold. At least some of the closure devices according to the present invention are repositionable and retrievable.

Claims

1. A device for closing a defect in septal tissue, comprising:

a first side adapted to be disposed on one side of the septal tissue and a second side adapted to be disposed on the opposite side of the septal tissue, said first and second sides connected by two flexible center joints extending from the first side to the second side,

wherein each of said first and second sides includes an anchor member, and

wherein the anchor member of at least one of said first and second sides comprises a generally cylindrical member having a central portion, wherein the central portion is split to form an elongate oval having a surface area adapted to seat against the septal tissue.

2. The device accordingly to claim 1, wherein the first anchor member includes a tissue scaffold attached to generally cylindrical member, wherein the center joint is further attached to the tissue scaffold such that the longitudinal axis of the generally cylindrical member extends generally transverse to the center joint when the device is deployed.

3. The device according to claim 2, wherein the tissue scaffold is bioresorbable.