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Device and methods for coupling/uncoupling a target or an object present in a sample

  • US 8,758,576 B2
  • Filed: 05/17/2004
  • Issued: 06/24/2014
  • Est. Priority Date: 05/21/2003
  • Status: Expired due to Fees
First Claim
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1. A device comprising:

  • a support comprising a surface comprising an attachment zone (Z) functionalized with a probe (A) capable of binding to a target (B) so as to attach it;

    a working electrode (WE) and a counterelectrode (CE) for the working electrode, placed on the support in the vicinity of the attachment zone, wherein the working electrode surrounds the attachment zone;

    an empty space separating said attachment zone and said working electrode; and

    a means for applying a given electric current or a given potential to said working electrode so as to cause, when said attachment zone and said electrodes are immersed in an aqueous solution, a local variation in pH in the region of said attachment zone.

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