Transmembrane sensing device for sensing bladder condition

• US 8,761,888 B2
• Filed: 04/13/2011
• Issued: 06/24/2014
• Est. Priority Date: 07/29/2005
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Gerber, Martin T.
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): Dinga, Roland
• Application Number:
  US13/086,016
• Publication Number:
  US 20110190844A1
• Time in Patent Office: 1,168 Days
• Field of Search: 607/40, 607/41
• US Class Current: 607/41
• CPC Class Codes: A61B 5/204 Determining bladder volume
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control

Abstract

The disclosure describes a sensing device that is implantable to sense bladder conditions, as well as a neurostimulation system and method that make use of such a sensor for alleviation of urinary incontinence. The sensing device is implantable outside the bladder, but includes a lead that penetrates the bladder wall to deploy a sensor within the bladder. Using the sensor on the lead, the sensing device outside the bladder is able to detect a condition within the interior of the bladder. In this sense, the sensing device provides transmembrane sensing of internal bladder conditions. The condition may be indicative of bladder filling or bladder contraction, and may be used to control electrical stimulation applied to the patient to alleviate urinary incontinence.

Claims

1. A method comprising:

sensing a condition within an interior of a bladder from a position within the interior of the bladder via a sensor carried on a distal end of a lead and positioned within the interior of the bladder, the lead having an electrical conductor therein and extending, via penetration of a wall of the bladder, from the interior of the bladder to a sensing device implanted outside of the bladder;

generating, via a processor within the sensing device, information based on the bladder condition within the interior of the bladder sensed by the sensor from the position within the interior of the bladder; and

delivering, via an implantable stimulator, electrical stimulation therapy based on the information.

2. The method of claim 1, wherein delivering electrical stimulation therapy comprises delivering electrical stimulation therapy for urinary incontinence based on the information.

3. The method of claim 1, wherein the sensed bladder condition includes at least one of a bladder size or bladder pressure.

4. The method of claim 1, wherein the sensed bladder condition includes at least one of a bladder fill level or bladder contraction.

5. The method of claim 1, further comprising transmitting the sensed bladder condition to an external programmer that is configured to control the implantable stimulator to deliver electrical stimulation therapy for urinary incontinence based on the information.

6. The method of claim 1, further comprising detecting, via the sensor, impedance within the interior of the bladder, wherein the impedance is indicative of a bladder fill level, and wherein generating information based on the bladder condition comprises generating information based on the detected impedance.

7. The method of claim 1, wherein the sensing device is attached to an exterior surface of the bladder.

8. The method of claim 1, wherein the sensing device includes a power supply.

9. The method of claim 1, wherein the sensor includes at least one of an impedance sensor, an ultrasonic sensor, or a pressure sensor.

10. An implantable electrical stimulation system comprising:

a sensing device adapted to be implanted outside of a bladder;

a lead having an electrical conductor therein and adapted to extend from the sensing device into an interior of the bladder via penetration of a wall of the bladder;

a sensor, adapted to be carried at a distal end of the lead and positioned within the interior of the bladder, wherein the sensor is configured to sense a condition within the interior of the bladder from the position within the interior of the bladder;

a processor within the sensing device, wherein the processor is configured to generate information based on the bladder condition within the interior of the bladder sensed by the sensor from the position within the interior of the bladder; and

an implantable stimulator that delivers electrical stimulation therapy based on the information.

11. The system of claim 10, further comprising an external programmer configured to control the delivery of the stimulation therapy in response to the information.

12. The system of claim 10, wherein the sensed bladder condition includes at least one of a bladder size or bladder pressure.

13. The system of claim 10, wherein the sensed bladder condition includes at least one of a bladder fill level or bladder contraction.

14. The system of claim 10, wherein the sensor includes at least one of an impedance sensor, an ultrasonic sensor, or a pressure sensor.

15. The system of claim 10, wherein the sensing device includes a power supply.

16. The system of claim 10, further comprising a fixation structure to attach the sensing device to an exterior surface of the bladder.

17. The system of claim 10, wherein the implantable stimulator configures the electrical stimulation therapy to alleviate urinary incontinence.

18. The system of claim 10, wherein the sensor comprises an impedance sensor adapted to be positioned within the interior of the bladder, wherein the impedance sensor is configured to detect impedance within the bladder, wherein the impedance is indicative of a bladder fill level, and wherein the processor is configured to generate the information by at least generating the information based on the detected impedance.