Determination of the effective lens position of an intraocular lens using aphakic refractive power

• US 8,764,187 B2
• Filed: 07/13/2010
• Issued: 07/01/2014
• Est. Priority Date: 07/14/2009
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: WaveTec Vision Systems, Inc. (Alcon Incorporated)
• Inventors: Padrick, Thomas D., Holladay, Jack T.
• Primary Examiner(s): WILKES, ZACHARY W
• Application Number:
  US12/835,668
• Publication Number:
  US 20110015541A1
• Time in Patent Office: 1,449 Days
• Field of Search: 351/200, 351/205, 351/159.73, 351/159.78
• US Class Current: 351/159.78
• CPC Class Codes: A61B 3/0025 characterised by electronic signal processing, e.g. eye models
• CPC Class Codes: A61B 3/10 Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
• CPC Class Codes: A61B 3/1015 for wavefront analysis
• CPC Class Codes: A61B 3/103 for determining refraction, e.g. refractometers, skiascopes
• CPC Class Codes: A61F 2/16 Intraocular lenses
• CPC Class Codes: A61F 2/1662 Instruments for inserting intraocular lenses into the eye
• CPC Class Codes: G02C 7/022 Ophthalmic lenses having special refractive features achieved by special materials or material structures G02C7/049 takes precedence
• CPC Class Codes: G02C 7/024 Methods of designing ophthalmic lenses

Abstract

An ophthalmic method for determining a relationship between aphakic ocular power and estimated effective lens position (ELP) of an intraocular lens (IOL) to be implanted in a patient'"'"'s eye. The method can be used to determine an estimate of the ELP of an IOL given the aphakic ocular power of the patient'"'"'s eye, for example, without measurement of the corneal curvature or axial length of the patient'"'"'s eye. The estimate of ELP can then be used to determine a suitable value of optical power for the IOL to be implanted in the patient'"'"'s eye.

Claims

1. A method for determining the optical power of an intraocular lens to be inserted into the eye of a patient, the method comprising:

receiving as an input from an input device an aphakic refractive power value of the patient'"'"'s eye;

determining, with a processor, an estimate of the post-surgical effective lens position (ELP) of the intraocular lens for the patient'"'"'s eye, the estimate being based on the aphakic refractive power value of the patient'"'"'s eye and on a relationship between aphakic refractive power and post-surgical intraocular lens ELP; and

determining an amount of optical power for the intraocular lens to be inserted into the patient'"'"'s eye based on the estimate of the post-surgical ELP of the intraocular lens in the patient'"'"'s eye.

2. The method of claim 1, wherein the relationship between aphakic refractive power and post-surgical intraocular lens ELP is determined using regression analysis.

3. The method of claim 1, wherein the estimate of the post-surgical ELP of the intraocular lens is not based on measured corneal power of the patient'"'"'s eye.

4. The method of claim 1, wherein the estimate of the post-surgical ELP of the intraocular lens is not based on measured axial length of the patient'"'"'s eye.

5. The method of claim 1, wherein the aphakic refractive power value of the patient'"'"'s eye comprises an intraoperative measurement of the aphakic refractive power of the patient'"'"'s eye.

6. The method of claim 5, wherein the intraoperative measurement of the aphakic refractive power of the patient'"'"'s eye comprises the spherical equivalent power of the patient'"'"'s eye.

7. The method of claim 1, further comprising outputting the estimate of the post-surgical ELP of the intraocular lens.

8. The method of claim 1, further comprising outputting the amount of optical power for the intraocular lens.

9. The method of claim 1, wherein the estimate of the post-surgical ELP of the intraocular lens is based on the intraocular lens being inserted into the capsular bag of the patient'"'"'s eye.

10. The method of claim 1, wherein determining the estimate of the post-surgical ELP of the intraocular lens comprises calculating the estimate using a mathematical function that comprises the relationship between aphakic refractive power and intraocular lens ELP.

11. The method of claim 1, further comprising performing a measurement using the input device to determine the aphakic refractive power value of the patient'"'"'s eye.

12. The method of claim 1, wherein the input device comprises a wavefront sensor.

13. A non-transitory machine-readable medium that, when read by a machine, causes the machine to perform a method comprising:

receiving as an input an indication of the aphakic refractive power value of the patient'"'"'s eye;

determining an estimate of the post-surgical effective lens position (ELP) of the intraocular lens based on the aphakic refractive power value of the patient'"'"'s eye and on a relationship between aphakic refractive power and intraocular lens ELP; and

determining an appropriate amount of optical power for the intraocular lens to be inserted into the eye of the patient based on the estimate of the post-surgical ELP of the intraocular lens.

14. An ophthalmic method for determining a relationship between post-surgical effective lens position (ELP) of an intraocular lens and aphakic ocular power, the method comprising:

obtaining from an input device a plurality of aphakic power values of a respective plurality of eyes;

determining a plurality of post-surgical ELP values of an intraocular lens for the respective plurality of eyes; and

determining a relationship between the plurality of aphakic power values and the plurality of post-surgical ELP values using a processor.

15. The method of claim 14, further comprising performing a plurality of measurements using the input device to determine the plurality of aphakic power values of the plurality of eyes.

16. The method of claim 14, wherein the input device comprises a wavefront sensor.

17. The method of claim 14, wherein the plurality of aphakic power values of the respective plurality of eyes comprise a plurality of aphakic measurements of the aphakic power of the respective plurality of eyes.

18. The method of claim 14, wherein the plurality of aphakic power values of the respective plurality of eyes comprise a plurality of calculated values based on the respective corneal power and axial length of the respective plurality of eyes.

19. The method of claim 14, wherein determining a plurality of the post-surgical ELP values of an intraocular lens for the respective plurality of eyes comprises performing post-surgical measurements of the ELP for the respective plurality of eyes.

20. The method of claim 14, wherein determining a plurality of the post-surgical ELP values of an intraocular lens for the respective plurality of eyes comprises using an ELP estimation formula for the respective plurality of eyes.

21. The method of claim 20, wherein the ELP estimation formula comprises the Holladay 1, the Holladay 2, the SRK/T, the Hoffer Q, or the Hagis formula.

22. The method of claim 14, wherein determining a relationship between the plurality of aphakic power values and the plurality of post-surgical ELP values comprises mathematically modeling the relationship between the plurality of aphakic power values and the plurality of post-surgical ELP values of the intraocular lens.

23. The method of claim 22, wherein mathematically modeling the relationship comprises using regression analysis of the plurality of aphakic power values for the respective plurality of eyes and the plurality of post-surgical ELP values of an intraocular lens for the respective plurality of eyes to determine the relationship.

24. The method of claim 23, wherein using regression analysis comprises fitting a polynomial function whose independent variable corresponds to the plurality of aphakic power values for the respective plurality of eyes and whose dependent variable corresponds to the plurality of post-surgical ELP values of the intraocular lens for the respective plurality of eyes.

25. An ophthalmic instrument comprising:

a measurement device for measuring the aphakic power of a patient'"'"'s eye; and

a processor for performing a method comprising,

receiving an aphakic refractive power value of the patient'"'"'s eye from the measurement device,

determining an estimate of the post-surgical effective lens position (ELP) of an intraocular lens to be inserted in the patient'"'"'s eye, the estimate of the post-surgical ELP of the intraocular lens being based on the aphakic refractive power value of the patient'"'"'s eye and a general relationship between aphakic refractive power and intraocular lens ELP, and

determining an appropriate amount of optical power for the intraocular lens to be inserted into the patient'"'"'s eye based on the estimate of the post-surgical ELP of the intraocular lens.

26. The ophthalmic instrument of claim 25, wherein the measurement device comprises a wavefront aberrometer.

27. The ophthalmic instrument of to claim 26, wherein the wavefront aberrometer comprises a Talbot-moiré

wavefront aberrometer.

28. The ophthalmic instrument of claim 25, wherein the relationship between aphakic refractive power and post-surgical intraocular lens ELP is determined using regression analysis.

29. The ophthalmic instrument of claim 25, wherein the estimate of the post-surgical ELP of the intraocular lens is not based on measured corneal power of the patient'"'"'s eye.

30. The ophthalmic instrument of claim 25, wherein the estimate of the post-surgical ELP of the intraocular lens is not based on measured axial length of the patient'"'"'s eye.

31. The ophthalmic instrument of claim 25, wherein the aphakic refractive power value of the patient'"'"'s eye comprises an intraoperative measurement of the aphakic refractive power of the patient'"'"'s eye.

32. The ophthalmic instrument of claim 31, wherein the intraoperative measurement of the aphakic refractive power of the patient'"'"'s eye comprises the spherical equivalent power of the patient'"'"'s eye.

33. The ophthalmic instrument of claim 25, wherein the method performed by the processor further comprises outputting the estimate of the post-surgical ELP of the intraocular lens.

34. The ophthalmic instrument of claim 25, wherein the method performed by the processor further comprises outputting the amount of optical power for the intraocular lens.

35. The ophthalmic instrument of claim 25, wherein the estimate of the post-surgical ELP of the intraocular lens is based on the intraocular lens being inserted into the capsular bag of the patient'"'"'s eye.

36. The ophthalmic instrument of claim 25, wherein determining the estimate of the post-surgical ELP of the intraocular lens comprises calculating the estimate using a mathematical function that comprises the relationship between aphakic refractive power and intraocular lens ELP.