System, method and device for monitoring the condition of an internal organ
First Claim
1. A system for monitoring a state of a brain, the system comprising:
- at least one internal electrode constructed and arranged to be placed adjacent to at least a portion of the brain and in communication with a system handler to provide a measurement thereto of electrical properties of the brain;
the internal electrode being provided on an intracranial catheter that is constructed and arranged to be placed within the brain to monitor a condition of the brain as a measurement of electrical properties thereof;
an intracranial pressure sensor for monitoring intracranial pressure within the brain by providing a measurement of pressure of the brain; and
at least one exterior electrode placed proximate and exterior to the at least one internal electrode to generate a signal therebetween in order to return a state of blood flow-induced electrical properties of the brain, such that the electrical properties of the brain indicate the blood flow-induced status of the brain;
wherein the status of the brain is determine by performing a group delay or phase shift analysis between the measurement of pressure of the brain and the state of blood flow-induced electrical properties of the brain.
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Abstract
A system, method and device for monitoring the condition of an internal organ, such as a brain, by providing an internal electrode. The internal electrode is operatively connected to at least one surface, external, electrode, and a system handler. A signal is generated between the electrodes such that the electrical properties, including conductivity and impedance among others, can be measured at and across the electrodes. The electrode arrangement allows for continuous monitoring of an internal organ and, where desired, mapping of the electrical properties thereof. The system obtains pressure readings, nodal conductivity and/or electrode impedance to monitor, map and report the condition of the internal organ. A correlation procedure is provided for generating a graphical representation of the condition of an internal organ from the gathered data. A medical treatment method is also provided for monitoring the status of the brain, and includes providing an internal electrode for measuring electrical properties of the internal organ.
33 Citations
17 Claims
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1. A system for monitoring a state of a brain, the system comprising:
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at least one internal electrode constructed and arranged to be placed adjacent to at least a portion of the brain and in communication with a system handler to provide a measurement thereto of electrical properties of the brain; the internal electrode being provided on an intracranial catheter that is constructed and arranged to be placed within the brain to monitor a condition of the brain as a measurement of electrical properties thereof; an intracranial pressure sensor for monitoring intracranial pressure within the brain by providing a measurement of pressure of the brain; and at least one exterior electrode placed proximate and exterior to the at least one internal electrode to generate a signal therebetween in order to return a state of blood flow-induced electrical properties of the brain, such that the electrical properties of the brain indicate the blood flow-induced status of the brain; wherein the status of the brain is determine by performing a group delay or phase shift analysis between the measurement of pressure of the brain and the state of blood flow-induced electrical properties of the brain. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 15)
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12. A system for monitoring a status of a brain, the system comprising:
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a system handler that includes a mapping application and a scoring application that together map electrical properties of the brain and thereafter providing a score of the status of the brain; at least one internal electrode constructed and arranged to be placed adjacent to at least a portion of the brain and in communication with the system handler to provide a measurement thereto of electrical properties of the brain; at least one exterior electrode placed proximate and exterior to the at least one internal electrode to generate a signal therebetween in order to return a state of electrical properties of the brain, the state of the electrical properties of the brain indicating the status of the brain; the mapping application constructed and arranged to map electrical property lags in measurements of electrical properties of the brain to provide a graphical representation of the status of the brain including a group delay or phase shift analysis performed to provide the status of the brain by correlating intracranial pressure of the brain and blood flow, or a surrogate of blood flow as determined by flow-induced electrical properties of the brain, the graphical representation including a display of threshold regions that indicate the status of the brain; and the scoring application providing the score of the status of the brain based upon a scale of varying conditions. - View Dependent Claims (16)
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13. A system for monitoring a status of an internal organ, the system comprising:
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at least one internal electrode constructed and arranged to be placed adjacent to at least a portion of the internal organ; at least one exterior electrode constructed and arranged to be placed proximate and exterior to the at least one internal electrode to generate a signal therebetween in order to return a state of electrical properties of the internal organ, the electrical properties of the internal organ indicating the status of the internal organ; and a system handler constructed and arranged to; a) gather the electrical properties of the internal organ; b) perform a group delay or phase shift analysis between the changing electrical properties of the internal organ representing blood flow and changing intra-organ pressure to determine a lag therebetween within a region of interest in the internal organ; c) assign a score value corresponding to the status of the internal organ; and d) map the score value and corresponding region of interest to a category to provide a graphical representation of the status of the internal organ. - View Dependent Claims (14, 17)
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Specification