Systems and methods for making gelatin shunts

• US 8,765,210 B2
• Filed: 12/08/2011
• Issued: 07/01/2014
• Est. Priority Date: 12/08/2011
• Status: Active Grant

• Current Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Original Assignee: AqueSys, Inc. (Abbvie Incorporated)
• Inventors: Romoda, Laszlo O., Hamstrom, Brian, Chandrakant, Partha, Horvath, Christopher
• Primary Examiner(s): SELLMAN, CACHET I
• Application Number:
  US13/314,950
• Publication Number:
  US 20130149429A1
• Time in Patent Office: 936 Days
• Field of Search: 118/400, 118/422, 118402-403, 118/DIG.18, 427/355, 427/356, 427/379, 427/430.1, 427/4.3, 4274342-4347
• US Class Current: 427/2.24
• CPC Class Codes: A61F 2240/001 Designing or manufacturing processes
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: B05C 3/12 for treating work of indefinite length

Abstract

The invention generally relates to systems and methods for making gelatin shunts. In certain embodiments, the invention provides methods that may involve moving a wire through a bath including a bottom layer of liquid gelatin and a top layer of water, thereby coating the wire with gelatin, moving the gelatin coated wire through an aperture, and drying the gelatin on the wire in a humidity controlled space, thereby manufacturing a gelatin shunt. In other embodiments, the invention provides systems that may include a motor, a wire operable coupled to the motor for movement of the wire, a temperature controllable bath, an aperture plate situated in a top portion of the bath, and an ultrasonic fogger, in which the system is configured such that the wire moves through the bath, through the aperture plate, and into the ultrasonic fogger.

Claims

1. A method for manufacturing a gelatin shunt, the method comprising:

moving a wire through a bath comprising a bottom layer of liquid gelatin and a top layer of water, thereby coating the wire with gelatin;

moving the gelatin coated wire through an aperture; and

drying the gelatin on the wire in a humidity controlled space, thereby manufacturing a gelatin shunt.

2. The method according to claim 1, wherein after the drying, the shunt comprises a uniform shape and a uniform cross-section.

3. The method according to claim 1, wherein the liquid gelatin comprises a drug.

4. The method according to claim 1, wherein the moving comprises mechanically controlling the wire.

5. The method according to claim 1, further comprising controlling humidity of the space by drying the gelatin on the wire in the presence of an ultrasonic water fog.

6. The method according to claim 1, wherein the aperture is in the water layer.

7. The method according to claim 1, wherein the moving comprises moving the wire vertically through the bath.

8. The method according to claim 1, wherein the gelatin coated wire extends vertically during the drying step.

9. The method according to claim 1, wherein the manufactured shunt is sized and dimensioned to be an intraocular shunt.