System and method of preventing the delivery of hypoxic gases to a patient

• US 8,770,192 B2
• Filed: 01/10/2011
• Issued: 07/08/2014
• Est. Priority Date: 01/10/2011
• Status: Active Grant

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Tham, Robert Q.
• Primary Examiner(s): DOUGLAS, STEVEN O
• Application Number:
  US12/987,544
• Publication Number:
  US 20120174926A1
• Time in Patent Office: 1,275 Days
• Field of Search: 128/204.18, 12820421-20423, 128/204.26, 128/204.28, 12820511-20513, 128/205.17, 128/205.24
• US Class Current: 128/204.21
• CPC Class Codes: A61M 16/0045 Means for re-breathing exhaled gases, e.g. for hyperventilation treatment
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/01 specially adapted for anaesthetising A61M16/104, A61M16/18 take precedence
• CPC Class Codes: A61M 16/024 including calculation means, e.g. using a processor
• CPC Class Codes: A61M 16/0891 Closed circuit, e.g. for anaesthesia
• CPC Class Codes: A61M 16/12 by mixing different gases
• CPC Class Codes: A61M 16/122 with dilution
• CPC Class Codes: A61M 16/125 Diluting primary gas with ambient air
• CPC Class Codes: A61M 16/18 Vaporising devices for anaesthetic preparations
• CPC Class Codes: A61M 16/209 Relief valves
• CPC Class Codes: A61M 16/22 Carbon dioxide-absorbing devices ; Other means for removing carbon dioxidecartridges with absorbing substances for respiratory apparatus A62B19/00
• CPC Class Codes: A61M 2016/1025 the O2 concentration
• CPC Class Codes: A61M 2016/1035 the anaesthetic agent concentration
• CPC Class Codes: A61M 2202/0208 Oxygen
• CPC Class Codes: A61M 2202/0241 Anaesthetics; Analgesics
• CPC Class Codes: A61M 2202/025 Helium
• CPC Class Codes: A61M 2202/0283 Nitrous oxide (N2O)
• CPC Class Codes: A61M 2202/0291 Xenon
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 : with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2230/43 : Composition of exhalation

Abstract

A system for preventing the delivery of hypoxic gases during respiratory support of a patient includes a breathing circuit. An input device is operable by a clinician to input at least one ventilator parameter value. A fresh gas manifold is pneumatically connected to the breathing circuit and the fresh gas manifold is configured to provide at least oxygen and balanced gas to the breathing circuit. A digital signal processor is communicatively connected to the input device and the fresh gas manifold. The digital signal processor receives the input at least one ventilation parameter value, calculate a predicted oxygen concentration, and compares the predicted oxygen concentration to a predetermined minimal oxygen required threshold of the patient. A method of preventing the delivery of hypoxic gases to a patient includes providing ventilatory support to the patient through a breathing circuit. A digital signal processor receives a ventilation parameter value from an input device. The digital signal processor calculates a predicted oxygen concentration, compares the predicted oxygen concentration to a predetermined hypoxic concentration threshold and accepts the ventilation parameter value if the predicted oxygen concentration is above the predetermined hypoxic concentration threshold.

Claims

1. A system for preventing the delivery of hypoxic gases during respiratory support of a patient, the system comprising:

a breathing circuit including a patient connection configured to deliver respiratory support to the patient;

an input device operable by a clinician to input at least one ventilation parameter value;

a fresh gas manifold pneumatically connected to the breathing circuit, the fresh gas manifold configured to provide at least oxygen and a balance gas to the breathing circuit;

a mechanical ventilator pneumatically connected to the breathing circuit, the mechanical ventilator configured to create fluid pressure waveforms within the breathing circuit to provide respiratory support to the patient;

a digital signal processor communicatively connected to the input device, fresh gas manifold, and the mechanical ventilator, the digital signal processor receives the input at least one ventilation parameter value, calculates a predicted oxygen concentration delivered to the patient with the at least one ventilation parameter value, and compares the predicted oxygen concentration to a predetermined minimum oxygen requirement threshold of the patient;

wherein if the predicted oxygen concentration is above the predetermined minimum oxygen requirement threshold, the digital signal processor accepts the at least one ventilation parameter value; and

wherein if the predicted oxygen concentration is below the predetermined minimum oxygen requirement threshold, the digital signal processor rejects the at least one ventilation parameter value.

2. The system of claim 1, further comprising an output device, wherein if the digital signal processor rejects the at least one ventilation parameter value, the digital signal processor operates the output device to produce an alarm.

3. The system of claim 2, wherein a clinician can override the alarm with an input to the input device, and the digital signal processor accepts the at least one ventilator parameter value.

4. The system of claim 1, wherein if the digital signal processor rejects the at least one ventilation parameter value, the digital signal processor calculates at least one additional parameter value.

5. The system of claim 4, wherein the digital signal processor recalculates a new predicted oxygen concentration, and if the new predicted oxygen concentration is above the predetermined minimum oxygen requirement threshold, the digital signal processor accepts the at least one ventilation parameter value and at least one additional parameter value.

6. The system of claim 5, wherein the at least one ventilation parameter value comprises fresh gas flow rate and the at least one additional parameter value comprises fresh gas oxygen concentration.

7. The system of claim 5, wherein the at least one ventilation parameter value comprises fresh gas oxygen flow rate and the at least one additional parameter value comprises balance gas flow rate.

8. The system of claim 1, further comprising:

a respiratory gas monitor fluidly connected to the breathing circuit, the respiratory gas monitor produces a signal indicative of an oxygen concentration inhaled and exhaled by the patient.

9. The system of claim 8, wherein the digital signal processor calculates the predetermined minimum oxygen requirement threshold using at least one of the signal indicative of oxygen concentration inhaled and exhaled by the patient.

10. The system of claim 1, wherein the fresh gas manifold is connected to a nitrous oxide source and the nitrous oxide source provides the balance gas to the breathing circuit.

11. A low-flow ventilation system that provides repeating breaths of respiratory support to a patient while preventing the delivery of hypoxic gases to the patient, the system comprising:

a breathing circuit including a patient connection configured to deliver the respiratory support to the patient;

an input device operable by a clinician to input at least one ventilation parameter value;

a fresh gas manifold pneumatically connected to the breathing circuit, the fresh gas manifold configured to provide at least oxygen and a balance gas to the breathing circuit;

a digital signal processor communicatively connected to the input device and the fresh gas manifold, the digital signal processor receives the at least one ventilation parameter value, calculates a predicted oxygen concentration delivered to the patient with the at least one ventilation parameter value, and compares the predicted oxygen concentration to a predetermined minimum oxygen requirement threshold of the patient;

wherein if the predicted oxygen concentration is above the predetermined minimum oxygen requirement threshold, the digital signal processor accepts the at least one ventilation parameter value; and

wherein if the predicted oxygen concentration is below the predetermined minimum oxygen requirement threshold, the digital signal processor calculates at least one additional parameter value such that the predicted oxygen concentration is above the predetermined minimum oxygen requirement threshold, and the digital signal processor accepts the at least one ventilation parameter value and at least one additional parameter value.

12. The system of claim 11, wherein the at least one ventilation parameter value is selected from fresh gas flow rate, fresh gas oxygen concentration, fresh gas oxygen flow rate, and balance gas flow rate.

13. The system of claim 11, wherein the digital signal processor calculates the predetermined minimum oxygen requirement.

14. The system of claim 13, wherein the digital signal processor receives a value of patient oxygen uptake rate and calculates the predetermined minimum oxygen requirement from the value of patient oxygen uptake rate.

15. The system of claim 13, further comprising:

a respiratory gas monitor fluidly connected to the breathing circuit, the respiratory gas monitor produces a signal indicative of an oxygen concentration inhaled or exhaled by the patient;

wherein the digital signal processor calculates the predetermined minimum oxygen requirement using at least one of the oxygen concentration inhaled by the patient or the oxygen concentration exhaled by the patient.

16. A method of preventing the delivery of hypoxic gases to a patient receiving ventilatory support from low-flow mechanical ventilator, the method comprising:

providing ventilatory support to the patient through a breathing circuit pneumatically connected to a mechanical ventilator in a low-flow configuration;

receiving, with a digital signal processor, a ventilation parameter value from an input device connected to the digital signal processor;

calculating a predicted oxygen concentration delivered to the patient with the digital signal processor based upon the ventilation parameter value;

comparing the predicted oxygen concentration to a predetermined hypoxic concentration threshold with the digital signal processor;

accepting, with the digital signal processor, the ventilation parameter value if the predicted oxygen concentration is above the predetermined hypoxic concentration threshold;

rejecting, with the digital signal processor, the ventilation parameter value if the predicted oxygen concentration is below the predetermined hypoxic concentration threshold.

17. The method of claim 16, further comprising:

calculating at least one additional parameter value with the digital signal processor, the at least one additional parameter value resulting in the predicted oxygen concentration being above the predetermined hypoxic concentration threshold.

18. The method of claim 16, further comprising operating a graphical display with the digital signal processor to represent an alarm if the digital signal processor rejects the ventilation parameter value.

19. The method of claim 16, further comprising:

receiving a value of patient oxygen uptake with the digital signal processor; and

calculating the predetermined hypoxic concentration threshold from the received value of patient oxygen uptake.

20. The method of claim 19, further comprising:

receiving a value of oxygen concentration with the digital signal processor, the value of oxygen concentration measured by a respiratory gas monitor; and

calculating, with the digital signal processor, the predetermined hypoxic concentration threshold from the value of inspired oxygen concentration and the value of expired oxygen concentration.