Valve prosthesis fixation techniques using sandwiching
First Claim
1. A prosthesis for implantation at a native valve of a subject, the prosthesis comprising:
- a frame comprising;
a distal fixation member configured to be positioned at least partially on a downstream side of the native valve, and shaped so as to define two or more leaflet engagement arms that are configured to apply a first force to tissue of the subject on a downstream side of the native valve, wherein the leaflet engagement arms are configured to contact a downstream side of a leaflet of the native valve without contacting commissures of the native valve upon implantation of the prosthesis;
a proximal fixation member configured to be positioned at least partially on an upstream side of the native valve, at least a portion of the proximal fixation member being configured to contact an upstream side of the native valve upon implantation of the prosthesis, the proximal fixation member being configured to apply a second force to tissue of the subject on an upstream side of the native valve,wherein application of the first and second forces anchors the prosthesis to the native valve,wherein the leaflet engagement arms and the proximal fixation member are configured to capture leaflets of the native valve therebetween, upon implantation of the prosthesis; and
a prosthetic valve positioned inside and coupled to the frame.
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Accused Products
Abstract
A prosthesis including a distal fixation member that defines two or more engagement arms that are configured to apply a first axial force to tissue of the subject on a downstream side of the native valve complex. The prosthesis also includes a proximal fixation member configured to apply a second axial force to tissue of the subject on an upstream side of the native valve complex such that application of the first and second axial forces couples the prosthesis to the native valve complex. The proximal fixation member and the distal fixation member are fabricated as one integrated structure. The engagement arms and the proximal fixation member are configured to capture leaflets of the native valve complex therebetween without folding over of leaflets of the native valve complex, upon implantation of the prosthesis.
1038 Citations
25 Claims
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1. A prosthesis for implantation at a native valve of a subject, the prosthesis comprising:
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a frame comprising; a distal fixation member configured to be positioned at least partially on a downstream side of the native valve, and shaped so as to define two or more leaflet engagement arms that are configured to apply a first force to tissue of the subject on a downstream side of the native valve, wherein the leaflet engagement arms are configured to contact a downstream side of a leaflet of the native valve without contacting commissures of the native valve upon implantation of the prosthesis; a proximal fixation member configured to be positioned at least partially on an upstream side of the native valve, at least a portion of the proximal fixation member being configured to contact an upstream side of the native valve upon implantation of the prosthesis, the proximal fixation member being configured to apply a second force to tissue of the subject on an upstream side of the native valve, wherein application of the first and second forces anchors the prosthesis to the native valve, wherein the leaflet engagement arms and the proximal fixation member are configured to capture leaflets of the native valve therebetween, upon implantation of the prosthesis; and a prosthetic valve positioned inside and coupled to the frame. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
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Specification