Spirocyclic heterocycles medicaments containing said compounds, use thereof and method for their production
First Claim
1. A method for the treatment of a disease of the airways accompanied by increased production of mucus, wherein the disease is selected from chronic bronchitis, chronic obstructive bronchitis (COPD), asthma, bronchiectasis, allergic or non-allergic rhinitis or sinusitis, cystic fibrosis, α
- 1-antitrypsin deficiency, coughs, pulmonary emphysema, pulmonary fibrosis and hyperreactive airways, comprising administering to a patient a therapeutically effective amount of a compound of formula (I)
0 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to spirocyclic heterocycles of general formula (I)
the tautomers, the stereoisomers, the mixtures thereof and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways, and the preparation thereof.
102 Citations
9 Claims
-
1. A method for the treatment of a disease of the airways accompanied by increased production of mucus, wherein the disease is selected from chronic bronchitis, chronic obstructive bronchitis (COPD), asthma, bronchiectasis, allergic or non-allergic rhinitis or sinusitis, cystic fibrosis, α
- 1-antitrypsin deficiency, coughs, pulmonary emphysema, pulmonary fibrosis and hyperreactive airways, comprising administering to a patient a therapeutically effective amount of a compound of formula (I)
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
Specification