Embolus blood clot filter with bio-resorbable coated filter members

• US 8,777,975 B2
• Filed: 12/29/2006
• Issued: 07/15/2014
• Est. Priority Date: 12/30/2005
• Status: Active Grant

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Kashkarov, Alexander Germanovich, Chanduszko, Andrzej J.
• Primary Examiner(s): Woo, Julian W
• Assistant Examiner(s): David, Shaun L
• Application Number:
  US12/096,788
• Publication Number:
  US 20130006294A1
• Time in Patent Office: 2,755 Days
• Field of Search: 600/200, 128/831, 607/128, 623/1.36
• US Class Current: 606/200
• CPC Class Codes: A61F 2/0103 With centering means
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2210/0004 bioabsorbable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body

Abstract

A blood clot filter includes a number of locator members and anchor members, each of the members tipped with a retainer encompassed within bio-resorbable cover material. Upon delivery into a blood vessel, the locator and anchor members position the filter near the vessel centerline. After a period of time, the bio-resorbable cover material resorbs, allowing the retainer on the members to penetrate and attach to the vessel wall. A method of implanting the filter includes delivering the filter into a blood vessel and allowing the bio-resorbable cover material to resorb so retainers on the members can engage the vessel walls.

Claims

1. A filter to be placed in a blood vessel, the filter comprising:

a) a plurality of appendages, each appendage having a curved anchor with a sharp free end tip;

b) a bio-resorbable mass of material that encapsulates the entire anchor including the sharp free end tip, wherein said mass of material has an outer surface that is smooth for enabling the mass of material to slide along the inside of the vessel; and

c) wherein the curved anchor of at least one of the plurality of appendages has a deformed configuration so as to be generally linear, the curved anchor being encapsulated by the bio-resorbable material to maintain the curved anchor in the deformed configuration.

2. The filter according to claim 1, wherein the bio-resorbable material is coated by a water repellant coating.

3. The filter according to claim 2, wherein the water repellant coating is activated by radiation to become at least partially porous.

4. The filter according to claim 3, wherein the water repellant coating is activated by radiation having a wavelength of approximately 800 nm.

5. A filter to be placed in a blood vessel, the filter comprising:

a) a plurality of appendages, each appendage having a curved anchor with a sharp free end tip;

b) a bio-resorbable mass of material that encapsulates the entire anchor including the sharp free end tip, wherein said mass of material has an outer surface that is smooth for enabling the mass of material to slide along the inside of the vessel;

c) a hub coupled to the plurality of appendages the plurality of appendages further comprising a plurality of locator members that locate the filter with respect to a wall of the blood vessel; and

d) a plurality of anchor members coupled to the hub, at least one of the plurality of anchor members having a retainer configured to penetrate a wall of the blood vessel when the filter is disposed in the blood vessel, wherein a bio-resorbable material encompasses at least a portion of the retainer of the at least one of the plurality of anchor members, and

e) the retainer is held by the mass of bio-resorbable material in a first linear position, moving to a second curved position when the bio-resorbable material resorbs.

6. The filter according to claim 5, wherein the anchor has a hook shape in said second position.

7. A filter to be placed in a blood vessel, the filter comprising:

a) a plurality of appendages, each appendage having a curved anchor with a sharp free end tip;

b) a bio-resorbable mass of material that encapsulates the entire anchor including the sharp free end tip, wherein said mass of material has an outer surface that is smooth for enabling the mass of material to slide along the inside of the vessel;

c) a hub disposed along a longitudinal axis, the hub being coupled to the plurality of appendages; and

wherein the appendages are each coupled to the hub, each curved anchor spaced along the longitudinal axis from the hub at a first longitudinal distance, and radially spaced from the longitudinal axis a first radial distance, each curved anchor being configured to penetrate a wall of the blood vessel when the filter is disposed in the blood vessel, and

wherein the plurality of appendages include a plurality of locator members, each locator member including;

a first portion proximate the hub;

a second portion that extends from the first portion along a first axis;

a third portion that extends from the second portion along a second axis distant from the first axis; and

wherein each curved anchor comprises a hook having a curved configuration in an operative condition and a generally linear configuration in a constrained condition, wherein the bio resorbable material maintains the hook in the linear configuration until the bio resorbable material is resorbed.

8. The filter according to claim 7 wherein:

the second portion extends from the first portion a first length along the first axis, which is oblique with respect to the longitudinal axis; and

the third portion extends a second length along the second axis, wherein the second length is greater than the first length, and the second axis is oblique with respect to the longitudinal axis.

9. The filter according to claim 7, wherein the first portion of each of the plurality of locator members includes a curved portion defining a radius of curvature, the first portion forming a first angle with respect to the longitudinal axis.

10. The filter according to claim 9, wherein the first axis defines a second angle with respect to the longitudinal axis, the second axis defines a third angle with respect to the longitudinal axis, the first angle being greater than each of the second and third angles.

11. The filter according to claim 10, wherein the first angle is about 60 degrees, the second angle is about 20 degrees and the third angle is less than about 1 degree.

12. The filter according to claim 7, wherein the hub includes a retrieving hook.