Clot capture systems and associated methods

• US 8,777,976 B2
• Filed: 07/22/2009
• Issued: 07/15/2014
• Est. Priority Date: 07/22/2008
• Status: Active Grant

• Current Assignee: Neuravi Limited (Johnson & Johnson)
• Original Assignee: Neuravi Limited (Johnson & Johnson)
• Inventors: Brady, Eamon, Razavi, Mahmood, Vale, David, O'Shaughnessy, John
• Primary Examiner(s): Erezo, Darwin
• Assistant Examiner(s): YABUT, DIANE D
• Application Number:
  US12/737,527
• Publication Number:
  US 20110125181A1
• Time in Patent Office: 1,819 Days
• Field of Search: 606/113, 606/127, 606/200
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/22035 for retrieving or repositioning foreign objects
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22051 with an inflatable part, e.g. balloon, for positioning, blocking, or immobilisation A61B2017/22048, A61B2017/3486 take precedence
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2215 having an open distal end
• CPC Class Codes: A61B 2017/2217 single wire changing shape to a gripping configuration
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0058 X-shaped

Abstract

A clot capture system for disengaging a clot 2001 from a vessel wall 2002 and removing the clot 2001 from the vessel 202, includes a clot capture device 2140 for placement on a distal side of a clot 2001. The clot capture device 2140 has a retracted delivery configuration and an expanded deployed configuration. The clot removal device has a proximal support frame 2012, and a distal fiber net 2130. The support frame 2012 has a retracted delivery configuration and an expanded deployed configuration. The proximal support frame 2012 in the expanded configuration defines a proximal inlet mouth for engaging a clot 2001 and a net 2130 for confining the clot 2001. An elongate member facilitates capture and/or withdrawal of a clot 2001 from a vessel 2002. The system also includes a clot debonding device 2091 for placement on a proximal side of a clot 2001. The clot debonding device 2091 has a retracted delivery configuration and an expanded deployed configuration and includes a clot engagement element 2112 which defines a distal abutment in the deployed configuration for urging a clot 2001 into the clot capture device 2140.

Claims

1. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration in which it may be advanced across said obstructive clot, the device comprising:

an expandable clot retrieval portion configured for deployment on a distal side of the clot, the clot retrieval portion having a plurality of struts forming at least one hoop;

an expandable portion configured for deployment on a proximal side of the clot, the expandable portion having a plurality of struts and a proximally tapering portion at a proximal end of the expandable portion, and the expandable portion being connected to the clot retrieval portion by a plurality of connecting elements;

a clot receiving space between the clot retrieval portion and the expandable portion; and

a longitudinally-extending member extending through the clot receiving space and coupled to the clot retrieval portion, wherein a central axis of the longitudinally-extending member is located along a central axis of both the clot retrieval portion and the expandable portion, wherein

the clot removal device includes a clot retrieval configuration during withdrawal of the expandable clot retrieval portion into a catheter that is smaller than the expanded deployed configuration of the expanded clot removal device, the clot retrieval configuration maintaining the clot receiving space between the clot retrieval portion and the expandable portion.

2. The clot removal device of claim 1, wherein the clot receiving space in the clot retrieval configuration corresponds to a length of the plurality of connecting elements from a proximal-most end to a distal-most end.

3. The clot removal device of claim 1, wherein the clot retrieval portion includes a distally tapering distal end portion.

4. The clot removal device of claim 1, wherein the plurality of struts of the expandable portion are formed by a distal end portion of a tubular member, the plurality of struts defining openings through the expandable portion between the plurality of struts.

5. The clot removal device of claim 1, wherein the expandable portion is connected to the clot retrieval portion by two connecting elements.

6. The clot removal device of claim 1, wherein the expandable portion includes a circumferential zig zag structure, and the plurality of connecting elements are coupled at a base of the zig zag structure.

7. The clot removal device of claim 6, wherein the plurality of connecting elements are connected to a proximal-most portion of the clot retrieval portion.

8. The clot removal device of claim 1, wherein the longitudinally-extending member extends distally beyond the distal end of the clot retrieval portion.

9. A clot removal device for restoring blood flow to a vessel occluded by an obstructive clot, the device having an expanded deployed configuration, and a retracted delivery configuration in which it may be advanced across said obstructive clot, the device comprising:

an expandable clot retrieval portion configured for deployment on a distal side of the clot, the clot retrieval portion having a plurality of struts forming at least one hoop;

an expandable portion configured for deployment on a proximal side of the clot, the expandable portion having a plurality of struts and a proximally tapering portion at a proximal end of the expandable portion, and the expandable portion being directly connected to the clot retrieval portion by a plurality of connecting elements;

a clot receiving space between the clot retrieval portion and the expandable portion; and

a longitudinally-extending member extending through the clot receiving space and coupled to the clot retrieval portion, wherein a central axis of the longitudinally-extending member is located along a central axis of both the clot retrieval portion and the expandable portion, wherein

the clot removal device includes a clot retrieval configuration during withdrawal of the expandable clot retrieval portion into a catheter that is smaller than the expanded deployed configuration of the expanded clot removal device, the clot retrieval configuration maintaining the clot receiving space between the clot retrieval portion and the expandable portion.

10. The clot removal device of claim 9, wherein the clot receiving space in the clot retrieval configuration corresponds to a length of the plurality of connecting elements from a proximal-most end to a distal-most end.

11. The clot removal device of claim 9, wherein the clot retrieval portion includes a distally tapering distal end portion.

12. The clot removal device of claim 9, wherein the expandable portion includes a plurality of struts formed by a distal end portion of a tubular member, the plurality of struts defining openings through the expandable portion between the plurality of struts.

13. The clot removal device of claim 9, wherein the expandable portion is connected to the clot retrieval portion by two connecting elements.

14. The clot removal device of claim 9, wherein the expandable portion includes a circumferential zig zag structure, and the plurality of connecting elements are coupled at a base of the zig zag structure.

15. The clot removal device of claim 14, wherein the plurality of connecting elements are connected to a proximal-most portion of the clot retrieval portion.

16. The clot removal device of claim 9, wherein the longitudinally-extending member extends distally beyond the distal end of the clot retrieval portion.