System and method for mechanically positioning intravascular implants

• US 8,777,979 B2
• Filed: 09/30/2011
• Issued: 07/15/2014
• Est. Priority Date: 04/17/2006
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Shrivastava, Sanjay, Slee, Earl, Moret, Olivier
• Primary Examiner(s): Erezo, Darwin
• Assistant Examiner(s): HOLLM, JONATHAN A
• Application Number:
  US13/251,021
• Publication Number:
  US 20120041470A1
• Time in Patent Office: 1,019 Days
• Field of Search: 606/1, 606/108, 606/195, 606/200, 623/1.11, 128/831, 128/843
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12154 having stretch limiting means
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61B 2090/08021 of the patient or his organs

Abstract

Intravascular implant delivery systems and methods are described. One such system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Claims

1. An assembly for deploying an implant into an aneurysm in a vessel, comprising:

a tubular member having a longitudinal axis, a wall defining a lumen along the axis, and a distal portion having an inner cross-sectional dimension and a distal end;

a coil implant having an enlarged proximal end; and

a monolithic core wire extending within the lumen and contacting the enlarged end at a point, the core wire comprising a distalmost end region having a cross-section that is, in a plane transverse to the longitudinal axis and intersecting the point, substantially crescent shaped;

wherein a length of a line segment extending from an outer surface of the enlarged end, through the point, and to an outer surface of the core wire is greater than the inner cross-sectional dimension, such that the enlarged end is prevented from moving within the lumen distally entirely past the distal end when the core wire and enlarged end are positioned radially adjacent each other within the lumen;

wherein, prior to release of the coil implant from the tubular member, and when the enlarged end is unable to move within the lumen distally entirely past the distal end, the distalmost end region of the core wire extends distally and radially inward from a side of the lumen, contacted by the outer surface of the core wire, and into the distal end and beyond a distalmost portion of the distal end.

2. The assembly of claim 1, wherein the cross-section has a concave first side facing toward the enlarged end.

3. The assembly of claim 2, wherein the first side contacts the enlarged end when the core wire contacts the enlarged end.

4. The assembly of claim 1, wherein the cross-section has a convex second side facing away from the enlarged end.

5. The assembly of claim 4, wherein the second side contacts the wall when the core wire contacts the enlarged end.

6. The assembly of claim 4, wherein the core wire comprises at least one segment tapering from a first cross-sectional dimension to a second, smaller cross-sectional dimension.

7. An assembly for deploying an implant into an aneurysm in a vessel, comprising:

a tubular member having a longitudinal axis, a wall defining a lumen along the axis, and a distal portion having an inner cross-sectional dimension and a distal end;

a coil implant having an enlarged proximal end; and

a core wire extending within the lumen and contacting the enlarged end at a point;

wherein a length of a line segment extending from an outer surface of the enlarged end, through the point, and to an outer surface of the core wire is greater than the inner cross-sectional dimension, such that the enlarged end is prevented from moving within the lumen distally entirely past the distal end when the core wire and enlarged end are positioned radially adjacent each other within the lumen; and

wherein a region of the wall circumferentially encloses the enlarged proximal end and the core wire and has a non-circular cross-sectional shape in a plane perpendicular to the longitudinal axis and intersecting the point, wherein the core wire is restrained by the wall from moving about a circumference of the lumen while the core wire is contacting the enlarged end, such that the enlarged end, while contacting the core wire, is configured to move axially within the lumen relative to the tubular member.

8. The assembly of claim 7, wherein the region has a substantially oval cross-sectional shape in the plane.

9. The assembly of claim 7, wherein the tubular member has an outer profile with a substantially circular cross-sectional shape in the plane.

10. The assembly of claim 7, wherein a thickness of the tubular member varies at the region.

11. The assembly of claim 7, wherein the coil implant further comprises (i) a coil having a proximal portion and a distal portion and (ii) a stretch-resistant member extending through the coil and having a proximal end and a distal end, the stretch-resistant member distal end coupled to the coil distal portion, wherein the enlarged proximal end is disposed at the proximal end of the stretch-resistant member and is otherwise free of the proximal portion of the coil.

12. An assembly for deploying an implant into an aneurysm in a vessel, comprising:

a tubular member having (i) a longitudinal axis, (ii) a wall defining a lumen along the axis, (iii) an aperture through the wall and having an aperture cross-sectional dimension, (iv) an arm extending from an edge of the aperture, covering a portion of the aperture, and curving radially inward toward the axis, and (v) a distal portion having a port with an inner cross-sectional dimension and a distal end;

a coil implant having an enlarged proximal end disposed at least partly in the portion of the aperture, the enlarged proximal end having a largest proximal end cross-sectional dimension that is less than the aperture cross-sectional dimension, wherein at least a portion of the coil implant extends through the port; and

a core wire extending within the lumen and contacting the enlarged end at a point;

wherein the arm is configured to bias the enlarged proximal end away from the aperture to prevent passage of the enlarged proximal end through the aperture;

wherein a length of a line segment extending from an outer surface of the enlarged end, through the point, and to an outer surface of the core wire is greater than the inner cross-sectional dimension, such that the enlarged end is prevented from moving within the lumen distally entirely past the distal end when the core wire and enlarged end are positioned radially adjacent each other within the lumen.

13. The assembly of claim 12, wherein no part of the arm extends a radial distance from the axis greater than an outer radius of the tubular member.

14. The assembly of claim 12, wherein a portion of the arm extends inward toward the axis to a radial distance from the axis less than an outer radius of the tubular member.

15. The assembly of claim 12, wherein the arm is in contact with the enlarged end when the enlarged end is within the aperture and contacting the core wire.

16. An assembly for deploying an implant into an aneurysm in a vessel, comprising:

a tubular member having a longitudinal axis, a wall defining a lumen along the axis, the lumen comprising (i) a distal portion having a cross-sectional dimension (ii) a distal end, and (iii) a reduced portion, proximal to the distal portion, having a non-circular first cross-sectional profile;

a coil implant having an enlarged proximal end; and

a core wire extending within the lumen through the reduced portion and contacting the enlarged end at a point, the core wire comprising an enlarged region having a second cross-sectional profile, wherein (i) travel of the enlarged region through the reduced portion is limited while in a first rotational state relative to the reduced portion and (ii) travel of the enlarged region through the reduced portion is permitted while in a second rotational state relative to the reduced portion;

wherein a length of a line segment extending from an outer surface of the enlarged end, through the point, and to an outer surface of the core wire is greater than the inner cross-sectional dimension, such that the enlarged end is prevented from moving within the lumen distally entirely past the distal end when the core wire and enlarged end are positioned radially adjacent each other within the lumen;

wherein the enlarged region has a proximal surface that is parallel to a distal surface of the reduced portion, the distal surface forming an oblique angle with respect to an axis of the core wire.

17. The assembly of claim 16, wherein the second cross-sectional profile is geometrically similar to the first cross-sectional profile.

18. The assembly of claim 16, wherein the second cross-sectional profile is congruent to a uniform scaling of the first cross-sectional profile.

19. The assembly of claim 16, wherein the second cross-sectional profile has substantially the same shape as the first cross-sectional profile.

20. The assembly of claim 16, wherein the second cross-sectional profile and the first cross-sectional profile comprise non-square rectangles.

21. The assembly of claim 16, wherein a portion of the core wire proximal to the enlarged region is compressively biased toward the reduced portion, such that distal movement of the core wire relative to the tubular member is restricted while the enlarged region is in the first rotational state.

22. The assembly of claim 16, wherein the reduced portion extends through an obstructing member within the lumen.

23. The assembly of claim 22, wherein a proximal surface of the enlarged region is substantially parallel to a distal surface of the obstructing member.

24. The assembly of claim 16, wherein the first rotational state comprises a first position of rotation of the enlarged region about the longitudinal axis.

25. An assembly for deploying an implant into an aneurysm in a vessel, comprising:

a tubular member having a longitudinal axis, a wall defining a lumen along the axis, an aperture through the wall, and a distal portion having an inner cross-sectional dimension and a distal end;

a coil implant having an enlarged proximal end, the enlarged end having (i) a primary portion residing in the lumen and (ii) a secondary portion extending from the primary portion into the aperture and engaging an edge of the aperture, wherein a first width of the secondary portion at a surface farthest from the primary portion is wider than a second width of the secondary portion, at a region of contact with the primary portion; and

a core wire extending within the lumen and contacting the enlarged end at a point;

wherein a length of a line segment extending from an outer surface of the enlarged end, through the point, and to an outer surface of the core wire is greater than the inner cross-sectional dimension, such that the enlarged end is prevented from moving within the lumen distally entirely past the distal end when the core wire and enlarged end are positioned radially adjacent each other within the lumen.

26. The assembly of claim 25, wherein a distal surface of the secondary portion engages a distal surface of the edge.

27. The assembly of claim 25, wherein the primary portion is substantially spherical.

28. The assembly of claim 25, wherein the secondary portion is substantially non-spherical.