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Swallowable capsule and method for stimulating incretin production within the intestinal tract

  • US 8,781,591 B2
  • Filed: 02/12/2014
  • Issued: 07/15/2014
  • Est. Priority Date: 08/03/2009
  • Status: Active Grant
First Claim
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1. A method for stimulating L-cells in an intestinal track of a patient to secrete a polypeptide, the method comprising:

  • ingesting a swallowable device configured to travel through the intestinal tract and electrically stimulate the L-cells at any location in the intestinal tract;

    delivering an electrical signal from the device to an intestinal wall proximate the device, wherein the signal includes a waveform configured to electrically stimulate the L-cells in the intestinal tract to secrete the polypeptide without substantially causing a peristaltic contraction.

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