Catheters with fluoropolymer additives

• US 8,784,402 B1
• Filed: 07/25/2013
• Issued: 07/22/2014
• Est. Priority Date: 03/15/2013
• Status: Active Grant

• Current Assignee: AngioDynamics, Inc., Evonik Canada Inc. (Rag-Stiftung)
• Original Assignee: AngioDynamics, Inc., Interface Biologics, Inc.
• Inventors: Lareau, Raymond, Bell, Benjamin, Santerre, J. Paul, Ho, Jeannette
• Primary Examiner(s): CAIN, EDWARD J
• Application Number:
  US13/950,585
• Time in Patent Office: 362 Days
• Field of Search: 524/423, 604/529, 604/523
• US Class Current: 604/529
• CPC Class Codes: A61L 29/049 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 29/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 29/14 Materials characterised by their function or physical properties , e.g. lubricating compositions
• CPC Class Codes: A61L 29/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61M 25/0108 using radio-opaque or ultrasound markers
• CPC Class Codes: C08L 27/12 containing fluorine atoms
• CPC Class Codes: C08L 75/04 Polyurethanes

Abstract

The present invention provides catheter compositions that provide anti-thrombogenic properties while not adversely impacting mechanical properties. All embodiments of the present invention comprise a catheter that comprises a fluoropolymer additive with specific compositions and/or purity levels.

Claims

1. A catheter comprising:

an elongated tubular structure comprising;

a polymeric material;

an outer surface, a proximal end, a distal end, and a lumen, wherein said outer surface and said lumen extend between said proximal and distal ends; and

a wall thickness between said outer surface and said lumen, said wall thickness being at least 0.005 inches;

wherein said polymeric material comprises polyurethane and additives, said additives comprising 25-35 weight percent of a radiopaque material, 1.5-2.5 weight percent of a polymer comprising terminal polyfluoro-oligomeric groups, and a colorant.

2. The catheter of claim 1, wherein said polymeric material is comprised of a positive amount of up to about 40 weight percent of said additives.

3. The catheter of claim 1, wherein said polymeric material is comprised of a positive amount of up to about 33 weight percent of said additives.

4. The catheter of claim 1, wherein said polymeric material comprises a positive amount of up to about 2.0 weight percent of said colorant.

5. The catheter of claim 4, wherein said polymeric material comprises a positive amount of up to about 0.2 weight percent of said colorant.

6. The catheter of claim 1, wherein said polymeric material comprises a positive amount of up to about 30 weight percent of said radiopaque material.

7. The catheter of claim 1, wherein said radiopaque material comprises barium sulfate.

8. The catheter of claim 1, wherein said elongated tubular structure comprises a plurality of lumens.