Transapical delivery system with ventruculo-arterial overlfow bypass

• US 8,784,478 B2
• Filed: 10/16/2007
• Issued: 07/22/2014
• Est. Priority Date: 10/16/2006
• Status: Active Grant

• Current Assignee: Medtronic Ventor Technologies LTD. (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: Tuval, Yosi, Benary, Raphael
• Primary Examiner(s): McDermott, Corrine M
• Assistant Examiner(s): Templeton, Christopher L
• Application Number:
  US12/445,824
• Publication Number:
  US 20110112631A1
• Time in Patent Office: 2,471 Days
• Field of Search: 623/2.11, 623 124- 126, 604/9, 604/4.01, 604/6.1, 604/6.11, 604/6.16, 604/5.01, 604/8, 604/7
• US Class Current: 623/2.11
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 17/3498 Valves therefor, e.g. flapper valves, slide valves haemostasis valves A61M39/06; check valves A61M39/24
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00252 for by-pass connections, i.e. connections from heart chamber to blood vessel or from blood vessel to blood vessel
• CPC Class Codes: A61M 25/003 characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves catheter tips A61M25/0067

Abstract

Apparatus is provided for implanting a prosthetic device (108) in a patient, the apparatus includes a trocar tube (101), a first portion of which is configured to be placed in a left ventricle (12) of the patient during a procedure for implantation of the prosthetic device (108), and a second portion of which is configured to be placed in an extracardiac location during the procedure. The first portion is shaped so as to define at least one opening to an interior thereof. One or more flexible bypass tubes (103, 104, 106), each of which is coupled to the second portion, and each of which is configured to be coupled to at least one artery (20, 21, 30) of the patient, so as to create a blood flow bypass path during the procedure, from the left ventricle (12), via the opening and the bypass tubes (103, 105, 106), to the at least one artery (20, 21, 30). Other embodiments are also described.

Claims

1. A method for implanting a prosthetic device in a patient, the method comprising:

transmyocardially advancing a trocar tube housing a prosthesis into a left ventricle of a subject, wherein the prosthesis restricts drainage of blood from the left ventricle into an opening at a distal end of the trocar tube when the prosthesis is housed in the trocar tube;

advancing the prosthesis through a valve of the patient, wherein advancing the prosthesis frees the opening in the distal end of tube, thereby allowing blood from the left ventricle to drain into an interior of the trocar tube; and

during the advancing of the prosthesis, providing a blood flow bypass path from the left ventricle of the patient, into the opening at the distal end of the trocar tube, through at least a portion of the interior of the trocar tube, and to an extracardiac arterial site downstream from the valve.

2. The method according to claim 1, wherein transmyocardially advancing the trocar tube comprises transmyocardially advancing the trocar tube through a free wall of the heart.

3. The method according to claim 1, wherein transmyocardially advancing the trocar tube comprises transapically advancing the tube into the left ventricle of the patient.

4. The method according to claim 1, wherein advancing the prosthesis comprises pushing a distal end of the trocar tube through the valve of the patient.

5. The method according to claim 1, further comprising allowing the prosthesis to expand following the advancing of the prosthesis through the valve.

6. The method according to claim 1, wherein the valve includes an aortic valve, wherein advancing the prosthesis through the valve comprises advancing the prosthesis through the aortic valve, and wherein providing the blood flow bypass path comprises providing the blood flow bypass path from the left ventricle to a descending aorta of the patient.

7. The method according to claim 1, wherein the valve includes an aortic valve, wherein advancing the prosthesis through the valve comprises advancing the prosthesis through the aortic valve, and wherein providing the blood flow bypass path comprises providing the blood flow bypass path from the left ventricle to a femoral artery of the patient.

8. The method according to claim 1, wherein the valve includes an aortic valve, wherein advancing the prosthesis through the valve comprises advancing the prosthesis through the aortic valve, and wherein providing the blood flow bypass path comprises providing the blood flow bypass path from the left ventricle to an iliac artery of the patient.

9. The method according to any one of claims 1-8, further comprising restricting blood flow through the valve during the advancing of the prosthesis therethrough.

10. The method according to claim 9, wherein providing a blood flow bypass path comprises draining blood from the left ventricle to the extracardiac site in response to the restricting.

11. The method according to claim 10, wherein draining the blood comprises actively draining the blood.

12. The method according to claim 10, wherein restricting the blood flow comprises increasing a contractile force of the left ventricle, and wherein draining the blood comprises allowing the blood to be passively drained through the trocar tube in response to the increasing.