Microfabricated neurostimulation device
First Claim
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1. An implantable neurological probe comprising:
- a cylindrical member having a distal end, a proximal end, and an internal lumen;
a flexible planar substrate comprising;
a first insulative layer,a microelectrode film,an extension including a plurality of wire lead contacts,a plurality of microelectrode elements disposed on an outer surface of the microelectrode film,a plurality of conductive traces to selectively couple the plurality of microelectrode elements to the plurality of wire lead contacts, anda plurality of wires to electrically couple the plurality of wire lead contacts to a proximal end of the probe;
wherein the microelectrode film of the flexible planar substrate is coupled to an outer surface of the cylindrical member with the extension of the flexible planar substrate extending in the internal lumen toward the proximal end of the cylindrical member, andwherein the plurality of wire lead contacts are disposed within the internal lumen such that at least a portion of the extension of the flexible planar substrate is disposed in the internal lumen.
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Abstract
Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an elongated probe shaft. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as deep within a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.
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22 Claims
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1. An implantable neurological probe comprising:
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a cylindrical member having a distal end, a proximal end, and an internal lumen; a flexible planar substrate comprising; a first insulative layer, a microelectrode film, an extension including a plurality of wire lead contacts, a plurality of microelectrode elements disposed on an outer surface of the microelectrode film, a plurality of conductive traces to selectively couple the plurality of microelectrode elements to the plurality of wire lead contacts, and a plurality of wires to electrically couple the plurality of wire lead contacts to a proximal end of the probe; wherein the microelectrode film of the flexible planar substrate is coupled to an outer surface of the cylindrical member with the extension of the flexible planar substrate extending in the internal lumen toward the proximal end of the cylindrical member, and wherein the plurality of wire lead contacts are disposed within the internal lumen such that at least a portion of the extension of the flexible planar substrate is disposed in the internal lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification