Devices to resist migration and rotation of implants used in brachytherapy and other radiation therapy

• US 8,790,235 B2
• Filed: 08/07/2009
• Issued: 07/29/2014
• Est. Priority Date: 07/22/2005
• Status: Expired due to Fees

• Current Assignee: Theragenics Corporation (Juniper Investment Co. LLC)
• Original Assignee: Eckert & Ziegler BEBIG S.A (Eckert & Ziegler AG)
• Inventors: Lamoureux, Gary A., Matons, James, Johnston, Warren, Bouffard, Matthew, Rice, Warren
• Primary Examiner(s): KUHLMAN, CATHERINE BURK
• Application Number:
  US12/538,028
• Publication Number:
  US 20090312594A1
• Time in Patent Office: 1,817 Days
• Field of Search: 600 1- 8, 600/37
• US Class Current: 600/8
• CPC Class Codes: A61N 2005/1023 Means for creating a row of seeds, e.g. spacers
• CPC Class Codes: A61N 2005/1024 Seeds
• CPC Class Codes: A61N 5/1027 Interstitial radiation therapy

Abstract

A therapeutic member for use in brachytherapy deliverable to an implant site by way of a needle comprises a single radioactive source encapsulated by a bio-absorbable material having an outer surface including one or more ribs encircling the single radioactive source, a leading edge endcap rib and a trailing edge endcap rib. The one or more ribs reduces a tendency of the member to migrate and rotate within a patient'"'"'s body after implantation. The encapsulating material further includes a first rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, and a second rail formed from the bio-absorbable material extending at least from opposite sides of the outer surface of the encapsulating material along the longitudinal axis of the therapeutic member, the second rail arranged in a plane substantially perpendicular to a plane in which the first rail is arranged. Another embodiment includes wings that selectively extend from an implant preventing movement of the implant.

Claims

1. An anchor mechanism, adapted for use with an implantable structure that is adapted to be implanted into patient tissue using a hollow needle, where the structure is a strand comprising at least one radioactive seed, the anchor mechanism comprising:

a main body having a main body diameter, a first longitudinal end and a second longitudinal end, and a bore that extends between the first and second longitudinal ends of the main body; and

a plurality of wings integrally formed with one of the first and second longitudinal ends of the main body and extending away from the main body in one of a leading and a trailing longitudinal direction without extending past the main body diameter;

wherein the anchor mechanism is adapted to be implanted into patient tissue adjacent the structure using the same hollow needle that is adapted to implant the structure into patient tissue; and

wherein the wings are biased such that at least a portion of the wings move outward past the main body diameter to engage surrounding patient tissue after the anchor mechanism is expelled from the hollow needle into patient tissue, to thereby reduce a tendency for both the anchor mechanism and the adjacent structure to migrate after implantation.

2. The anchor mechanism of claim 1, wherein:

the main body and the plurality of wings are connected by a living hinge.

3. The anchor mechanism of claim 1, wherein the anchor mechanism, including the main body and the plurality of wings, is made from a bio-absorbable material.

4. The anchor mechanism of claim 1, wherein:

an outer surface of the main body is cylindrical; and

the inner surface of the main body, which defines the bore, is cylindrical.

5. The anchor mechanism of claim 1, wherein:

the anchor mechanism has a closed position and an open position;

when in the closed position the anchor mechanism fits into a hollow needle that is adapted to implant the structure into patient tissue; and

the wings are biased such that anchor mechanism automatically transitions from the closed position to the open position when the anchor mechanism is expelled from the hollow needle.

6. The anchor mechanism of claim 1, wherein the main body is adapted to be attached to the structure.

7. The anchor mechanism of claim 1, wherein the bore is sized so that at least a portion of the structure fits into the bore, such that a further portion of the structure extends out from at least one of the first longitudinal end and the second longitudinal end of the main body.

8. The anchor mechanism of claim 1, wherein a diameter of the bore is slightly smaller than an outer diameter of the structure so that an interference fit is provided there between.

9. The anchor mechanism of claim 1, wherein main body is adapted to be heat shrunk to the structure.

10. The anchor mechanism of claim 1, wherein the main body is adapted to be adhered to the structure.

11. The anchor mechanism of claim 1, wherein the anchor mechanism is made from a non-bio-absorbable material which is bio-compatible.

12. An anchor mechanism, adapted for use with a radioactive seed that is adapted to be implanted into patient tissue using a hollow needle, the anchor mechanism comprising:

a cylindrical main body having a main body diameter, a first end, a second end, and a bore that extends between the first and second ends of the cylindrical main body;

a plurality of wings integrally formed with one of the first and second ends of the cylindrical main body and extending away from the cylindrical main body in one of a leading and a trailing longitudinal direction without extending past the main body diameter; and

wherein the anchor mechanism is adapted to be implanted into patient tissue adjacent the radioactive seed using the same hollow needle that is adapted to implant the radioactive seed into patient tissue;

wherein the anchor mechanism has a closed position and an open position;

wherein when in the closed position the anchor mechanism fits into the hollow needle that is adapted to implant the radioactive seed into patient tissue; and

wherein the wings are biased such that wings automatically move from the closed position outward to the open position past the main body diameter, after the anchor mechanism is expelled from the hollow needle into patient tissue, to thereby reduce a tendency for both the anchor mechanism and the adjacent radioactive seed to migrate after implantation.

13. The anchor mechanism of claim 12, wherein:

the cylindrical main body and the plurality of wings are connected by a living hinge.

14. The anchor mechanism of claim 12, wherein the anchor mechanism, including the cylindrical main body and wings, is made from a bio-absorbable material.

15. The anchor mechanism of claim 12, wherein the cylindrical main body is adapted to be attached to the adjacent radioactive seed.

16. The anchor mechanism of claim 12, wherein the bore is sized so that at least a portion of the radioactive seed fits into the bore and such that a further portion of the radioactive seed extends out from one of the first and second ends of the cylindrical main body.

17. The anchor mechanism of claim 12, wherein a diameter of the bore is slightly smaller than an outer diameter of the radioactive seed so that an interference fit is provided there between.

18. The anchor mechanism of claim 12, wherein the anchor mechanism is made from a non-bio-absorbable material which is bio-compatible.