Ventricular volume reduction

• US 8,790,242 B2
• Filed: 10/26/2010
• Issued: 07/29/2014
• Est. Priority Date: 10/26/2009
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Cardiokinetix Incorporated
• Inventors: Kermode, James R., Alexander, Miles D., Boutillette, Michael P., Davila, Matthew T., Tan, Irene Bing Bie
• Primary Examiner(s): LACYK, JOHN P
• Application Number:
  US12/912,632
• Publication Number:
  US 20110098525A1
• Time in Patent Office: 1,372 Days
• Field of Search: 600/37, 600 16- 18
• US Class Current: 600/37
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 2017/0053 Loading magazines or sutures into applying tools
• CPC Class Codes: A61F 2/2487 Devices within the heart chamber, e.g. splints
• CPC Class Codes: A61M 2205/32 with radio-opaque indicia
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 25/0067 characterised by the distal end, e.g. tips A61M25/0054, A61M25/04 take precedence; balloon catheters A61M25/10
• CPC Class Codes: A61M 25/0068 Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 60/17 inside a ventricle, e.g. intraventricular balloon pumps
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/289 Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices
• CPC Class Codes: A61M 60/295 Balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/468 the force acting on the actuation means being hydraulic or pneumatic
• CPC Class Codes: A61M 60/47 the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
• CPC Class Codes: A61M 60/497 for balloon pumps for circulatory assistance
• CPC Class Codes: A61M 60/833 Occluders for preventing backflow
• CPC Class Codes: A61M 60/861 Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body
• CPC Class Codes: A61M 60/865 Devices for guiding or inserting pumps or pumping devices into the patient's body
• CPC Class Codes: A61M 60/867 using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter

Abstract

Devices and systems including implants (which may be removable) and methods of using them for reducing ventricular volume. The implants described herein are cardiac implants that may be inserted into a patient'"'"'s heart, particularly the left ventricle. The implant may support the heart wall, or may be secured to the heart wall. The implants are typically ventricular partitioning device for partitioning the ventricle into productive and non-productive regions in order to reduce the ventricular volume.

Claims

1. A ventricular volume reduction implant for insertion into a patient'"'"'s ventricle to reduce the active volume of the ventricle wherein the height of the implant can be adjusted to adjust the reduction volume, the implant comprising:

a partitioning membrane configured to span across the ventricle to partition the ventricle; and

a support frame comprising an adjustable-height stem region, the support frame comprises a plurality of support struts, wherein adjusting the height of the stem region adjusts the height of the partitioning membrane within the ventricle;

wherein the adjustable-height stem region comprises a lock to lock the stem in a predetermined height, and

wherein the implant is configured to be inserted in a collapsed configuration and expanded into a deployed configuration within the ventricle.

2. The device of claim 1, wherein the adjustable-height stem region comprises a movable collar configured to adjust the height.

3. The implant of claim 1, wherein at least one of the struts comprises a locating strut having a radiopaque marker.

4. A ventricular volume reduction implant for insertion into a patient'"'"'s ventricle wherein the height of the implant can be adjusted, the implant comprising:

a partitioning membrane configured to span across the ventricle to partition the ventricle;

a foot region configured to be inserted near an apex of the ventricle; and

a support frame comprising an adjustable-height stem region, wherein the support frame comprises a plurality of support struts, wherein adjusting the height of the stem region adjusts the height of the partitioning membrane relative to the foot region;

wherein the adjustable-height stem region comprises a lock to lock the stem in a predetermined height, and

wherein the implant is configured to be inserted in a collapsed configuration and expanded into a deployed configuration within the ventricle.

5. The device of claim 4, wherein the adjustable-height stem region comprises a movable collar configured to adjust the height.

6. The device of claim 4, wherein the lock comprises locking tabs for securing a movable collar to the stem.

7. The implant of claim 4, wherein at least one of the struts comprises a locating strut having a radiopaque marker.

8. A ventricular volume reduction implant for insertion into a patient'"'"'s ventricle to reduce the active volume of the ventricle wherein the height of the implant can be adjusted to adjust the reduction volume, the implant comprising:

a partitioning membrane configured to span across the ventricle to partition the ventricle; and

a support frame comprising an adjustable-height stem region, the support frame comprises a plurality of support struts, wherein adjusting the height of the stem region adjusts the height of the partitioning membrane within the ventricle;

wherein the adjustable-height stem region comprises a movable collar configured to adjust the height, and

wherein the implant is configured to be inserted in a collapsed configuration and expanded into a deployed configuration within the ventricle.