Electronic endoscope system and processor unit thereof, and method for obtaining blood vessel information

• US 8,790,251 B2
• Filed: 01/28/2011
• Issued: 07/29/2014
• Est. Priority Date: 03/26/2010
• Status: Active Grant

• Current Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Original Assignee: Fujifilm Corporation (Fujifilm Holdings Corporation)
• Inventors: Yamaguchi, Hiroshi
• Primary Examiner(s): Nguyen, Anhtuan T
• Assistant Examiner(s): CHOU, WILLIAM B
• Application Number:
  US13/016,671
• Publication Number:
  US 20110237915A1
• Time in Patent Office: 1,278 Days
• Field of Search: 600/109, 600/118, 600/126, 600/178, 600/323, 600/410, 600/473, 600/475, 600/476, 600/477
• US Class Current: 600/160
• CPC Class Codes: A61B 1/000094 extracting biological structures
• CPC Class Codes: A61B 1/0005 combining images e.g. side-by-side, superimposed or tiled
• CPC Class Codes: A61B 1/00186 with imaging filters
• CPC Class Codes: A61B 1/0051 with controlled bending of insertion part
• CPC Class Codes: A61B 1/05 characterised by the image sensor, e.g. camera, being in the distal end portion
• CPC Class Codes: A61B 1/063 for monochromatic or narrow-band illumination
• CPC Class Codes: A61B 1/0638 providing two or more wavelengths
• CPC Class Codes: A61B 1/0646 with illumination filters
• CPC Class Codes: A61B 1/0655 Control therefor
• CPC Class Codes: A61B 1/0669 at proximal end of an endoscope
• CPC Class Codes: A61B 1/07 using light-conductive means, e.g. optical fibres
• CPC Class Codes: A61B 5/1076 for measuring dimensions inside body cavities, e.g. using catheters A61B3/1005 takes precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: G06T 2207/10068 Endoscopic image
• CPC Class Codes: G06T 2207/20221 Image fusion; Image merging
• CPC Class Codes: G06T 2207/20224 Image subtraction
• CPC Class Codes: G06T 2207/30101 Blood vessel; Artery; Vein; Vascular
• CPC Class Codes: G06T 5/50 using two or more images, e.g. averaging or subtraction
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

In a special light mode, first to fourth special images are captured under first to fourth special light being narrow band light. A brightness ratio calculator extracts a blood vessel area containing a blood vessel from each special image. The brightness ratio calculator calculates first to fourth brightness ratios from the special images on every pixel within the blood vessel area. A depth and hemoglobin index calculator calculates the depth of the blood vessel and a hemoglobin index corresponding to the first and second brightness ratios, based on a correlation between the depth of the blood vessel and the hemoglobin index stored in advance. A depth and oxygen saturation calculator calculates an oxygen saturation level corresponding to the third and fourth brightness ratios, based on a correlation between the depth of the blood vessel and the oxygen saturation level stored in advance.

Claims

1. An electronic endoscope system comprising:

a light applying section for applying at least three types of narrow band light having wavelengths within 400 nm to 600 nm as illumination light to an internal body part containing a blood vessel, two types of the illumination light out of the three types of the illumination light being narrow blue band light and narrow green band light;

an image sensor for capturing an image of the internal body part irradiated with the illumination light;

a blood vessel information obtaining section for obtaining blood vessel information based on a narrow band signal corresponding to the three types of the narrow band light, the blood vessel information including a depth of the blood vessel and a hemoglobin index,

a brightness ratio calculating section for calculating a first brightness ratio between the first narrow blue band signal and the second narrow blue band signal, and a second brightness ratio between the third narrow green band signal and the second narrow blue band signal; and

a memory for storing in advance a correlation between the depth of the blood vessel and the hemoglobin index with respect to the first and second brightness ratios,

wherein the three types of the illumination light includes first narrow blue band light, second narrow blue band light, and third narrow green band light; and

the narrow band signal corresponding to the three types of the narrow band light includes a first narrow blue band signal, a second narrow blue band signal, and a third narrow green band signal;

wherein, the blood vessel information obtaining section obtains based on the correlation stored in the memory the depth of the blood vessel and the hemoglobin index from the first and second brightness ratios.

2. The electronic endoscope system according to claim 1, wherein

the memory stores in advance a correlation between a brightness coordinate system representing the first and second brightness ratios and a blood vessel information coordinate system representing the depth of the blood vessel and the hemoglobin index;

and

the blood vessel information obtaining section plots coordinates of the first and second brightness ratios on the brightness coordinate system, and then reads out from the blood vessel information coordinate system coordinates of the depth of the blood vessel and the hemoglobin index corresponding to the plotted coordinates, to identify values of the depth of the blood vessel and the hemoglobin index.

3. The electronic endoscope system according to claim 1, wherein the first narrow blue band light has wavelengths of 405±

10 nm, and the second narrow blue band light has wavelengths of 470±

10 nm, and the third narrow green band light has wavelengths of 560±

10 nm.

4. The electronic endoscope system according to claim 1, wherein

the light applying section selectively emits the first narrow blue band light, the second narrow blue band light, and the third narrow green band light;

and

the image sensor captures the image under the first narrow blue band light to obtain the first narrow blue band signal of one frame, and captures the image under the second narrow blue band light to obtain the second narrow blue band signal of one frame, and captures the image under the third narrow green band light to obtain the third narrow green band signal of one frame.

5. The electronic endoscope system according to claim 1, wherein the light applying section includes:

a white light source for emitting white broad band light; and

a wavelength band limiting section disposed between the white light source and the image sensor, the wavelength band limiting section selectively extracting the three types of the narrow band light out of the broad band light.

6. The electronic endoscope system according to claim 5, wherein the wavelength band limiting section is an acoustic-optical tunable filter.

7. The electronic endoscope system according to claim 5, wherein the wavelength band limiting section is a rotary filter having a plurality of filters for selectively passing the three types of the narrow band light.

8. The electronic endoscope system according to claim 1, wherein the illumination light further includes fourth narrow blue band light having wavelengths of 440±

10 nm, and an oxygen saturation level in the blood vessel is obtained as the blood vessel information from a fourth narrow blue band signal corresponding to the fourth narrow blue band light.

9. A processor unit connected to an electronic endoscope comprising:

a receiving section for receiving an image signal from the electronic endoscope, the image signal being obtained by an image sensor for capturing an image of an internal body part containing a blood vessel, while the internal body part is irradiated with at least three types of narrow band light as illumination light, two types of the illumination light out of the three types of the illumination light being narrow blue band light and narrow green band light;

a blood vessel information obtaining section for obtaining blood vessel information based on a narrow band signal corresponding to the three types of the narrow band light, the blood vessel information including a depth of the blood vessel and a hemoglobin index,

a brightness ratio calculating section for calculating a first brightness ratio between the first narrow blue band signal and the second narrow blue band signal, and a second brightness ratio between the third narrow green band signal and the second narrow blue band signal; and

a memory for storing in advance a correlation between the depth of the blood vessel and the hemoglobin index with respect to the first and second brightness ratios,

wherein the three types of the illumination light includes first narrow blue band light, second narrow blue band light, and third narrow green band light; and

the narrow band signal corresponding to the three types of the narrow band light includes a first narrow blue band signal, a second narrow blue band signal, and a third narrow green band signal;

wherein, the blood vessel information obtaining section obtains based on the correlation stored in the memory the depth of the blood vessel and the hemoglobin index from the first and second brightness ratios.

10. A method for obtaining blood vessel information comprising the steps of:

applying at least three types of narrow band light having wavelengths within 400 nm to 600 nm as illumination light to an internal body part containing a blood vessel, two types of the illumination light out of the three types of the illumination light being narrow blue band light and narrow green band light;

capturing an image of the internal body part irradiated with the illumination light; and

obtaining blood vessel information based on a narrow band signal corresponding to the three types of the narrow band light, the blood vessel information including a depth of the blood vessel and a hemoglobin index,

a brightness ratio calculating section for calculating a first brightness ratio between the first narrow blue band signal and the second narrow blue band signal, and a second brightness ratio between the third narrow green band signal and the second narrow blue band signal; and

a memory for storing in advance a correlation between the depth of the blood vessel and the hemoglobin index with respect to the first and second brightness ratios,

wherein the three types of the illumination light includes first narrow blue band light, second narrow blue band light, and third narrow green band light; and

the narrow band signal corresponding to the three types of the narrow band light includes a first narrow blue band signal, a second narrow blue band signal, and a third narrow green band signal;

wherein, the blood vessel information obtaining section obtains based on the correlation stored in the memory the depth of the blood vessel and the hemoglobin index from the first and second brightness ratios.