Systems and methods for biofilm removal, including a biofilm removal endoscope for use therewith

• US 8,790,301 B2
• Filed: 06/13/2012
• Issued: 07/29/2014
• Est. Priority Date: 03/01/2007
• Status: Active Grant

• Current Assignee: Medtronic Xomed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Xomed Incorporated (Medtronic Plc)
• Inventors: Slenker, Dale E., Lewis, Cecil O., Norman, Gerould W., Prisco, John R.
• Primary Examiner(s): VU, QUYNH-NHU HOANG
• Application Number:
  US13/495,564
• Publication Number:
  US 20120253125A1
• Time in Patent Office: 776 Days
• Field of Search: 604/19, 604 21- 22, 604 27- 28, 604/35, 604/39, 604 43- 44, 604/48, 604/500, 604/514, 604/516, 604/164.01, 604/164.12, 606/101, 606/129, 606/139, 606/153
• US Class Current: 604/109
• CPC Class Codes: A61B 1/00091 Nozzles
• CPC Class Codes: A61B 1/012 characterised by internal passages or accessories therefor
• CPC Class Codes: A61B 1/0125 Endoscope within endoscope
• CPC Class Codes: A61B 1/015 Control of fluid supply or evacuation
• CPC Class Codes: A61B 1/12 with cooling or rinsing arrangements
• CPC Class Codes: A61B 1/227 for ears, i.e. otoscopes
• CPC Class Codes: A61B 1/233 for the nose, i.e. nasoscopes , e.g. testing of patency of Eustachian tubes
• CPC Class Codes: A61B 17/3203 Fluid jet cutting instruments
• CPC Class Codes: A61M 1/76 Handpieces specially for suction-irrigation A61M1/774, aspiration tips A61M1/84

Abstract

Systems and methods of removing bacterial biofilm from a target site using a biofilm removal endoscope. The endoscope has an insertion portion including an imaging channel terminating at a viewing window and an irrigation channel terminating at a nozzle. The imaging and irrigation channels are permanently affixed relative to one another. The insertion portion is inserted into the patient, with a working end thereof being disposed proximate the target site. The target site is imaged and a flow of fluid is dispensed via the nozzle to mechanically remove bacterial biofilm from the target site.

Claims

1. A system for removal of bacterial biofilm from a target site of a human patient, the system comprising:

a biofilm removal endoscope including;

a handle,

a controller maintained by the handle,

an insertion portion adapted for bodily insertion and including a working end, the insertion portion forming;

an imaging channel terminating at a viewing window formed in the working end that facilitates imaging of the target site, and

an irrigation channel terminating at a nozzle, the nozzle including a tubular body defining a base end assembled to the working end and an opposite leading end projecting distally beyond the viewing window, the tubular body converging along an axis that extends from the base end to an opening in the leading end that is centrally formed relative to the axis, the nozzle coupled with the controller to rotate the nozzle relative to the working end about the axis,

wherein the endoscope is configured such that pressurized fluid delivered through the irrigation channel is directed by the nozzle away from the viewing window to impinge upon a layer of bacterial biofilm at the target site.

2. The system of claim 1, wherein the irrigation channel and the imaging channels are permanently affixed relative to one another.

3. The system of claim 1, wherein the insertion portion includes a flexible distal segment.

4. The system of claim 1, wherein at least a segment of the insertion portion is substantially malleable such that the insertion portion is selectively bendable relative to the handle, and further wherein the nozzle is secured to the working end such that the nozzle can be aimed in a desired direction with bending of the insertion portion.

5. The system of claim 1, wherein the insertion portion further forms an aspiration channel terminating at an aspiration inlet formed adjacent the viewing window.

6. The system of claim 5, further comprising:

a source of pressurized fluid fluidly connected to the irrigation channel;

a vacuum source fluidly connected to the aspiration channel.

7. The system. of claim 1, wherein the opening is a V-cut opening.

8. The system of claim 1, wherein the leading end is hemispherical.

9. The system of claim 1, wherein the nozzle is a fan spray-type nozzle that produces a line of mechanical disruption at the target site.