Dose setting mechanism for a drug delivery device

• US 8,790,315 B2
• Filed: 05/28/2010
• Issued: 07/29/2014
• Est. Priority Date: 06/01/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Plumptre, David
• Primary Examiner(s): STIGELL, THEODORE J
• Application Number:
  US13/375,185
• Publication Number:
  US 20120165751A1
• Time in Patent Office: 1,523 Days
• Field of Search: 604/187, 604207-211
• US Class Current: 604/207
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member

Abstract

The invention relates to a dose setting mechanism, which is operable to be coupled to a medication cartridge and which comprises means that prevent the user from setting a dose greater than the remaining medication in the cartridge. The dose setting mechanism comprises a shaft. A helical groove having a first pitch is provided along a first portion of the shaft. The dose setting mechanism further comprises a nut member disposed on the helical groove of said shaft. During dose setting, the shaft is rotated relative to the nut member while the nut member traverses along the groove from a distal end of the shaft towards a proximal end of the shaft. The mechanism further comprises means preventing a user of said dose setting mechanism from setting a dose of said medication that is greater than said remaining medication in said cartridge, said means comprising a second pitch provided along a second portion of said shaft, wherein said first pitch is different from said second pitch, wherein said second pitch is preferably greater than said first pitch.

Claims

1. A dose setting mechanism for a drug delivery device, with a cartridge of medication, wherein the dose setting mechanism is operable to select a dose of medication which shall be administered out of said cartridge, the dose setting mechanism comprising:

a shaft comprising a helical thread having three separate portions, a first portion having a first pitch followed by a second portion having a second pitch that is larger than the first pitch and a third portion following the second portion having a third pitch that is less than the second pitch;

a nut member disposed on said helical thread of said shaft,

wherein during dose setting of said drug delivery device, said shaft is rotated relative to said nut member while said nut member traverses in longitudinal direction along said helical thread from a first end of said shaft towards a second end of said shaft;

where the nut member and shaft are configured to engage each other to form a stop mechanism to prevent a user of said dose setting mechanism from setting a dose of said medication that is greater than said remaining medication in said cartridge, the stop mechanism further comprising a radial stop face on the nut member, and a counter radial stop face on the shaft configured to engage the radial stop face on the nut member to prevent the shaft from rotating relative to the nut member.

2. The mechanism of claim 1 wherein the relative movement of shaft and nut member comprises a start position and a stop position of shaft and nut member relative to each other, wherein the displacement distance of the nut member between said start position and said stop position along the shaft corresponds to the amount of medication contained in said cartridge.

3. The mechanism of claim 1 wherein when said dose is dispensed from said cartridge, said nut member does not rotate relative to said shaft but rather both said nut member and said shaft move in a substantially axial direction, wherein said nut member comprises at least one spline feature, said at least one spline feature preventing relative rotation between said nut member and a housing of said drug delivery device.

4. The mechanism of claim 1 wherein said nut member comprises a partial thread, two half turns of a two start thread.

5. The mechanism of claim 1 wherein said first portion is located near a proximal end of said shaft and said second portion is located near a distal end of said shaft.

6. The mechanism of claim 1 wherein said nut member comprises a plurality of substantially radial stop faces, said plurality of radial stop faces engaging a plurality of substantially radial stop faces on said shaft.

7. The mechanism of claim 1 wherein said drug delivery device comprises a non-reusable pen type drug delivery device.

8. The mechanism of claim 1 wherein said nut member is a complete circular nut.

9. The mechanism of claim 1, wherein the second portion begins at a location corresponding to the last 45 to 360 degrees of rotation when the shaft is rotated relative to said nut member prior the nut member reaches the stop position.

10. The mechanism of claim 1 wherein said first end of said shaft comprises a distal end and said second end of said shaft comprises a proximal end.

11. The mechanism of claim 1 wherein the shaft is rotatable and the nut member is non-rotating.

12. A drug delivery device comprising a dose setting mechanism according to claim 1 and a cartridge of medication.