Bone oxygenation measurement

• US 8,792,951 B1
• Filed: 02/23/2010
• Issued: 07/29/2014
• Est. Priority Date: 02/23/2010
• Status: Active Grant

• Current Assignee: ViOptix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: Mao, Jimmy Jian-Min, Lash, Robert E.
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US12/711,010
• Time in Patent Office: 1,617 Days
• Field of Search: 600/310, 600/322, 600/323, 600/340, 600/344
• US Class Current: 600/340
• CPC Class Codes: A61B 2562/0238 Optical sensor arrangements for performing transmission measurements on body tissue
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/4504 Bones A61B5/4547 takes precedence
• CPC Class Codes: A61B 5/6847 mounted on an invasive device
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: Y10T 29/49002 Electrical device making
• CPC Class Codes: Y10T 29/49169 Assembling electrical component directly to terminal or elongated conductor

Abstract

A bone oximeter probe includes an elongated member and a sensor head at an end of the elongated member to make measurements for a bone. The measurements can indicate the viability or nonviability of the bone. In an implementation, the probe is advanced through an incision in soft tissue, towards the underlying bone, and positioned so that the sensor head faces the bone to be measured. Optical signals are sent from the sensor head and into the bone. The bone reflects some of the optical signals which are then detected so that measurements for the bone can be made. Some of these measurements include an oxygen saturation level value, and a total hemoglobin concentration value of the bone.

Claims

1. A method of making an oxygen saturation measurement for a bone comprising:

advancing an elongated probe through an incision in a tissue, wherein the probe comprises;

a first tube;

a sensor head, coupled to the first tube; and

first and second fiber optic cables, coupled to the sensor head, wherein ends of the first and second fiber optic cables are exposed on a surface of the sensor head, and an axis passing through the first tube passes through the surface;

positioning the elongated probe in the tissue so the sensor head contacts a bone for which an oxygen saturation parameter is to be measured;

causing transmitting of a first light signal through the first fiber optic cable to the sensor head, wherein from the sensor head, the first light signal is directed at the bone;

after causing transmitting of the first light signal through the first fiber optic cable, maintaining a position of the probe at the bone for the probe to receive a reflection of the first light signal from the bone, wherein the reflection of the first light signal from the bone is a second light signal; and

causing transmitting of the second light signal via the second fiber optic cable, wherein the second light signal is transmitted in a direction opposite of the transmitting of the first light signal.

2. The method of claim 1 wherein the sensor head comprises:

a first source opening, wherein the first fiber optic cable is coupled to the first source opening; and

a first detector opening, wherein the second fiber optic cable is coupled to the first detector opening, and a distance between the first source opening and the first detector opening is about 3.5 millimeters or less.

3. The method of claim 1 wherein the surface of the sensor head has a surface area of about 24 square millimeters or less.

4. The method of claim 1 wherein the probe further comprises:

a second tube, extending from a proximal end of the first tube to a connector for coupling the probe to a console, wherein the second tube comprises a flexible material and the first tube comprises a rigid material.

5. The method of claim 1 comprising:

coupling a connector of the probe to a console comprising an electronic display;

after causing transmitting of the first light signal through the first fiber optic cable and causing transmitting of the second light signal via the second fiber optic cable, causing a calculation in the console of an oxygen saturation parameter associated with the first light signal and second light signal; and

causing displaying of the oxygen saturation parameter on the electronic display.

6. The method of claim 5 wherein the oxygen saturation parameter comprises at least one of an oxygen saturation level value of the bone or a total hemoglobin concentration value of the bone that was measured.

7. The method of claim 1 wherein the fiber optic cables extend through a passageway within the probe to the sensor head.

8. The method of claim 1 wherein the sensor head comprises:

a first source structure;

a second source structure;

a first detector structure, wherein the first detector structure comprises the second fiber optic cable; and

a second detector structure, wherein a first distance extends between the first source structure and the first detector structure without touching another source or detector structure, a second distance extends between the second source structure and the second detector structure without touching another source or detector structure, and the first distance is different from the second distance.

9. The method of claim 1 wherein the sensor head comprises:

a first source structure comprising the first fiber optic cable;

a second source structure;

a first detector structure comprising the second fiber optic cable; and

a second detector structure, wherein the first source structure, second source structure, first detector structure, and second detector structure are arranged on a line and the axis is perpendicular to the line.

10. The method of claim 1 wherein the sensor head comprises:

a first source structure comprising the first fiber optic cable; and

a first detector structure comprising the second fiber optic cable, wherein distances between the first source structure and an edge of the surface and between the first detector structure and the edge are about 1.5 millimeters or less.

11. The method of claim 1 wherein the positioning the elongated probe in the tissue comprises positioning the elongated probe in the tissue so the sensor head contacts a first location on the bone, and the method further comprises:

after the causing transmitting of the second light signal, reading a first signal quality value on an electronic display of a console;

repositioning the elongated probe in the tissue so the sensor head contacts a second location on the bone, different from the first location; and

after the repositioning the elongated probe, reading a second signal quality value on the electronic display of the console.

12. The method of claim 1 wherein the sensor head comprises a deformable block,

wherein a surface of the sensor head can deform to adapt to a surface contour of the bone to be measured, and

the first and second optic cables that pass through the deformable block to the surface of the sensor head can slide within a passageway of the first tube as the deformable block is being deformed.

13. The method of claim 1 wherein the sensor head comprises at least a first, second, and third sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening, and

the first, second, and third openings are arranged in a line.

14. The method of claim 1 wherein the sensor head comprises at least a first, second, and third sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening, and

the first and second openings are arranged in a first line, and the second and third openings are arranged in a second line that is not in-line with the first line.

15. The method of claim 1 wherein the sensor head comprises at least a first, second, third, and fourth sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening, and

the first, second, and third openings are arranged in a line, and the fourth sensor opening is not in-line with the first, second, and third openings.

16. The method of claim 1 wherein the sensor head comprises at least a first, second, third, and fourth sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening, and

the first and second openings are separated by a first distance, the third and fourth openings are separated by a second distance, the second and third openings are separated by a third distance, and the third distance is greater than the first distance and the second distance.

17. The method of claim 1 wherein the sensor head comprises a first, second, third, and fourth sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening, and

the first, second, third, and fourth openings form corners of a quadrilateral shape, the first and second openings are separated by a first distance, the second and third openings are separated by a second distance, and the first distance is different from the second distance.

18. The method of claim 17 wherein the second and fourth openings are separated by a third distance, and the third distance is different from the first distance and second distance.

19. The method of claim 1 wherein the sensor head comprises four or fewer sensor openings on the surface, the sensor openings comprise a first and second sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening.

20. The method of claim 1 wherein the sensor head comprises three or fewer sensor opening on the surface, the sensor openings comprise a first and second sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening.

21. The method of claim 1 wherein the sensor head comprises at most two sensor openings on the surface, the sensor openings comprise a first and second sensor opening, the first fiber optic cable is coupled to the first sensor opening, and the second fiber optic cable is coupled to the second sensor opening.

22. The method of claim 1 wherein the surface of the sensor head is a first surface of the sensor head, the sensor head further comprises third and fourth fiber optic cables coupled to a second surface of the sensor head, and the second surface is not planar with the first surface.

23. The method of claim 1 wherein the surface of the sensor head is perpendicular to the axis passing through the first tube and the surface.

24. The method of claim 1 wherein the surface of the sensor head is not perpendicular to the axis passing through the first tube and the surface.