Inversion-based feed-forward compensation of inspiratory trigger dynamics in medical ventilators

• US 8,794,234 B2
• Filed: 09/24/2009
• Issued: 08/05/2014
• Est. Priority Date: 09/25/2008
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Jafari, Medhi M., Aviano, Jeffrey K., McCoy, Edward R., Jimenez, Rhomere S.
• Primary Examiner(s): Dixon, Annette
• Application Number:
  US12/566,119
• Publication Number:
  US 20100071697A1
• Time in Patent Office: 1,776 Days
• Field of Search: 128/200.24, 128/204.18, 128/204.21, 128/204.22, 128/204.23, 128/204.24, 128/204.26, 128/205.11
• US Class Current: 128/204.21
• CPC Class Codes: A61M 16/0063 Compressors
• CPC Class Codes: A61M 16/026 specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0027 pressure meter
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches

Abstract

A ventilator and method of ventilator control. The ventilator includes a pneumatic system for providing and receiving breathing gas, and a controller operatively coupled with the pneumatic system. The controller employs closed-loop control to provide positive breathing assistance to a patient. Supplemental feed-forward compensatory assistance is also provided, in addition to and independently of that commanded by the closed-loop control. The supplemental assistance may be determined, set or selected based on a ventilator parameter and/or an operator parameter, and/or as an automatic ongoing compensatory mechanism responding to varying patient respiratory demand.

Claims

1. A ventilator, comprising:

a pneumatic system for providing and receiving breathing gas;

a controller operatively coupled with the pneumatic system; and

an operator interface, where the controller is operable to;

execute a control scheme to command the pneumatic system to provide breathing gas to a patient during inspiration, where such breathing gas is provided in response to the ventilator detecting that the patient is attempting to initiate inspiration; and

command delivery of a feed-forward input of additional breathing gas corresponding to a desired boost pressure waveform to the patient during inspiration, where the feed-forward input is commanded in response to operator selection of at least one of a ventilator parameter and a patient parameter at the operator interface, and where the desired boost pressure waveform is continuously modeled based on performance measurements of the control scheme by adjusting a gain and at least one of an amount of time required to deliver a maximum flow and an exponential decay trajectory time constant.

2. The ventilator of claim 1, where the patient parameter enables specification of patient age.

3. The ventilator of claim 2, where the patient parameter enables specification that the patient is an adult patient.

4. The ventilator of claim 2, where the patient parameter enables specification that the patient is a pediatric patient.

5. The ventilator of claim 2, where the patient parameter enables specification that the patient is a neonatal patient.

6. The ventilator of claim 1, where the patient parameter enables specification of a patient disease condition.

7. The ventilator of claim 1, where the patient parameter enables specification of a physiological characteristic of the patient.

8. The ventilator of claim 1, where the ventilator parameter enables specification of characteristics of airway components used to couple the patient to the pneumatic system.

9. The ventilator of claim 1, where the ventilator parameter enables specification of characteristics of the pneumatic system.

10. A ventilator, comprising:

a pneumatic system for providing and receiving breathing gas; and

a controller operatively coupled with the pneumatic system, where the controller is operable to;

execute a control scheme to command the pneumatic system to provide breathing gas to a patient during inspiration;

receive a baseline closed-loop input corresponding to a desired output pressure of breathing gas from the pneumatic system;

receive an additional feed-forward input corresponding to a desired boost pressure waveform to be added to the desired output pressure, the additional feed-forward input being dependent upon at least one of an operator-selected ventilator parameter and an operator-selected patient parameter;

detect patient initiation of an inspiratory phase of a respiration cycle; and

during the inspiratory phase, command the pneumatic system to provide breathing gas based on the closed-loop input and the additional feed-forward input, the breathing gas being constrained through application of a feedback signal to the controller, where the desired boost pressure waveform is continuously modeled based on performance measurements of the control scheme by adjusting a gain and at least one of an amount of time required to deliver a maximum flow and an exponential decay trajectory time constant.

11. The ventilator of claim 10, further comprising an operator interface operatively coupled with the controller and configured to enable an operator to select at least one ventilator parameter and patient parameter.

12. The ventilator of claim 10, further comprising a patient breathing circuit and a physical patient interface configured to couple a patient to the pneumatic system.

13. The ventilator of claim 10, where the patient parameter includes specification of patient age.

14. The ventilator of claim 13, where the patient parameter includes specification that the patient is an adult patient.

15. The ventilator of claim 13, where the patient parameter includes specification that the patient is a pediatric patient.

16. The ventilator of claim 13, where the patient parameter includes specification that the patient is a neonatal patient.

17. The ventilator of claim 10, where the patient parameter includes specification of a patient disease condition.

18. The ventilator of claim 10, where the patient parameter includes specification of a physiological characteristic of the patient.

19. The ventilator of claim 10, where the ventilator parameter includes specification of characteristics of airway components used to fluidly couple the patient to the pneumatic system.

20. The ventilator of claim 10, where the ventilator parameter includes specification of characteristics of the pneumatic system.

21. A method of operating a patient-triggered, positive pressure ventilator, comprising:

driving a pneumatic system of the ventilator with a closed-loop control regime to provide positive pressure breathing assistance during inspiration;

providing a supplemental added pressure boost corresponding to a desired boost pressure waveform during inspiration in addition to the breathing assistance commanded by the closed-loop control regime; and

setting the supplemental added pressure boost based on operator input of at least one of a ventilator parameter and a patient parameter, where the desired boost pressure waveform is continuously modeled based on performance measurements of the closed-loop control regime by adjusting a gain and at least one of an amount of time required to deliver a maximum flow and an exponential decay trajectory time constant.

22. The method of claim 21, where the supplemental added pressure boost is applied during each of a plurality of respiration cycles, subsequent to patient-triggering of inspiration.

23. The method of claim 21, where the supplemental added pressure boost is tunable from one therapy session to the next, such that in a first therapy session, the positive pressure breathing assistance supplied by the closed loop-control regime is supplemented with a first supplemental added pressure boost, while during a second therapy session, the positive pressure breathing assistance supplied by the closed loop-control regime is supplemented with a second supplemental added pressure boost which is different from the first, such difference being based on a change in at least one of the ventilator parameter and the patient parameter.