System and method for determining pulmonary performance from transthoracic impedance measures
First Claim
1. A system for determining pulmonary performance from transthoracic impedance measures, comprising:
- an implantable medical device comprising a transthoracic impedance sensor configured to record one or more physiological measurements comprising transthoracic impedance measures;
a correlation component to correlate the physiological measurements to pulmonary functional measures, wherein the pulmonary functional measures are selected from forced vital capacity (FVC), forced expiratory volume (FEV), FEV to FVC ratio and combinations thereof;
a database module configured to store the correlated physiological measurements; and
an evaluation component to evaluate pulmonary performance, the evaluation component comprising;
an analysis subcomponent to determine differences in pulmonary performance by comparing the correlated physiological measurements to previously correlated and stored physiological measurements including physiological measurements taken during an initial observation period in which the transthoracic impedance sensor is calibrated and a baseline is established for the transthoracic impedance sensor; and
an identification module to identify a trend from the differences;
a processor programmed with the above components.
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Abstract
A system and method for determining pulmonary performance from transthoracic impedance measures is provided. Transthoracic impedance measures collected by an implantable medical device are correlated to pulmonary functional measures. The pulmonary functional measures are grouped by respiratory pattern. Pulmonary performance is evaluated. Differences are determined by comparing the pulmonary functional measures for each respiratory pattern to the pulmonary functional measures for at least one previous respiratory pattern. A trend is identified from the differences. An alert is generated upon sufficient deviation of the trend from a threshold criteria.
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Citations
16 Claims
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1. A system for determining pulmonary performance from transthoracic impedance measures, comprising:
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an implantable medical device comprising a transthoracic impedance sensor configured to record one or more physiological measurements comprising transthoracic impedance measures; a correlation component to correlate the physiological measurements to pulmonary functional measures, wherein the pulmonary functional measures are selected from forced vital capacity (FVC), forced expiratory volume (FEV), FEV to FVC ratio and combinations thereof; a database module configured to store the correlated physiological measurements; and an evaluation component to evaluate pulmonary performance, the evaluation component comprising; an analysis subcomponent to determine differences in pulmonary performance by comparing the correlated physiological measurements to previously correlated and stored physiological measurements including physiological measurements taken during an initial observation period in which the transthoracic impedance sensor is calibrated and a baseline is established for the transthoracic impedance sensor; and an identification module to identify a trend from the differences; a processor programmed with the above components. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A system for evaluating pulmonary performance using transthoracic impedance measures, comprising:
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an implantable medical device comprising a transthoracic impedance sensor configured to record physiological measurements comprising transthoracic impedance measures; a collection component to collect a set of physiological measurements; a profile component to form a pulmonary volume profile comprising pulmonary functional measures derived from the set of physiological measurements; a trend component to analyze trends by comparing the pulmonary volume profile with one or more previous pulmonary volume profiles; and an alert component to generate an alert upon substantial deviation of the trends from expected values of the pulmonary functional measures; wherein the pulmonary functional measures are selected from forced vital capacity (FVC), forced expiratory volume (FEV), FEV to FVC ratio and combinations thereof; a processor programmed with the above components. - View Dependent Claims (10, 11, 12, 13, 14, 15)
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16. A system for determining pulmonary performance from transthoracic impedance measures, comprising:
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an implantable medical device comprising a transthoracic impedance sensor configured to record one or more physiological measurements comprising transthoracic impedance measures; a correlation component to correlate the physiological measurements to pulmonary functional measures, the correlation component configured to determine the start of a breathing maneuver, wherein the pulmonary functional measures are selected from forced vital capacity (FVC), forced expiratory volume (FEV), FEV to FVC ratio and combinations thereof; a database module configured to store the correlated physiological measurements; and an evaluation component to evaluate pulmonary performance, the evaluation component comprising; an analysis subcomponent to determine differences in pulmonary performance by comparing the correlated physiological measurements to previously correlated and stored physiological measurements including physiological measurements taken during an initial observation period in which the transthoracic impedance sensor is calibrated and a baseline is established for the transthoracic impedance sensor; and an identification module to identify a trend from the differences; a processor programmed with the above components.
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Specification