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System and method for providing closed loop infusion formulation delivery

  • US 8,795,224 B2
  • Filed: 01/19/2011
  • Issued: 08/05/2014
  • Est. Priority Date: 09/07/2001
  • Status: Active Grant
First Claim
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1. A method for delivering an insulin formulation, the method comprising:

  • taking a plurality of samples of a blood glucose level over a period of time;

    calculating a difference between the blood glucose level of each of the plurality of samples and a predefined blood glucose level threshold;

    calculating a rate of change over time in the blood glucose level of each of the plurality of samples;

    calculating a sum comprising a first proportion of said calculated difference and a second proportion of said calculated rate of change, the second proportion including a trend term based on a timeframe; and

    delivering an amount of insulin formulation based on an amount of said sum,wherein the trend term is disabled if the blood glucose level of each of the plurality of samples is less than the predefined blood glucose level threshold.

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