Refill of implantable fluid delivery devices based on therapeutic fluid expiration

• US 8,795,260 B2
• Filed: 12/18/2009
• Issued: 08/05/2014
• Est. Priority Date: 12/18/2009
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Drew, Touby A.
• Primary Examiner(s): VU, QUYNH-NHU HOANG
• Application Number:
  US12/641,372
• Publication Number:
  US 20110152756A1
• Time in Patent Office: 1,691 Days
• Field of Search: 604/890.1, 604/891.1, 604/892.1, 604/65, 604/67, 604/93.01, 700/215, 700/225, 700299-300
• US Class Current: 604/890.1
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/40 for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades

Abstract

An expiration time of a therapeutic fluid delivered by an implantable fluid delivery device is employed to calculate a fill volume and determine a refill interval for the fluid. The expiration time of the therapeutic fluid may be based on or dictated by a stability time set by the manufacturer of the therapeutic fluid, a clinician treating a patient to whom the fluid is to be delivered, the manufacturer of the device delivering the fluid, or combinations thereof.

Claims

1. A method comprising:

determining a refill interval for a therapeutic fluid delivered by a fluid delivery device based on an expiration time for the therapeutic fluid;

wherein the expiration time comprises a period of time prescribed by a clinician; and

generating a refill indication based on the refill interval.

2. The method of claim 1, wherein generating a refill indication comprises generating a refill alarm upon expiration of the refill interval.

3. The method of claim 1, wherein generating a refill indication comprises generating a refill alarm in advance of expiration of the refill interval.

4. The method of claim 1, wherein the expiration time comprises a stability time for the therapeutic fluid.

5. The method of claim 1, further comprising determining a modified expiration time based on one or more environmental conditions under which the therapeutic fluid is stored and determining the refill interval for the therapeutic fluid delivered by the fluid delivery device based on the modified expiration time for the therapeutic fluid.

6. The method of claim 1, further comprising determining a modified expiration time based on a shelf-life of the therapeutic fluid and determining the refill interval for the therapeutic fluid delivered by the fluid delivery device based on the modified expiration time for the therapeutic fluid.

7. The method of claim 1, wherein the expiration time comprises a period of time prescribed by a manufacturer of the fluid delivery device based on empirical data for the therapeutic fluid.

8. The method of claim 1, wherein generating the refill indication comprises generating an alarm comprising one of an audible, tactile, or visual alert.

9. The method of claim 1, wherein generating the refill indication comprises vibrating the fluid delivery device.

10. The method of claim 1, wherein determining a refill interval for a therapeutic fluid delivered by a fluid delivery device based on an expiration time for the therapeutic fluid comprises:

determining a refill interval based on a volume of the therapeutic fluid to be stored in the fluid delivery device;

comparing the fluid volume based refill interval to the expiration time;

and at least one of setting the refill interval for the therapeutic fluid to the lesser of the fluid volume based refill interval and the expiration time or displaying the volume based refill interval and the expiration time.

11. The method of claim 1, wherein the fluid delivery device is at least partially implantable.

12. The method of claim 1, wherein the fluid delivery device comprises a fluid delivery pump and an implantable catheter connected to the fluid delivery pump and configured to deliver the therapeutic fluid to a patient.

13. The method of claim 12, wherein the fluid delivery pump comprises one of an external or implantable fluid delivery pump.

14. A method comprising:

determining a refill interval for a therapeutic fluid delivered by a fluid delivery device based on an expiration time for the therapeutic fluid; and

generating a refill indication based on the refill interval, wherein generating the refill indication comprises vibrating the fluid delivery device.

15. A method comprising:

determining a refill interval for a therapeutic fluid delivered by a fluid delivery device based on an expiration time for the therapeutic fluid;

wherein determining the refill interval comprises determining the refill interval based on a volume of the therapeutic fluid to be stored in the fluid delivery device;

comparing the fluid volume based refill interval to the expiration time; and

at least one of setting the refill interval for the therapeutic fluid to the lesser of the fluid volume based refill interval and the expiration time or displaying the volume based refill interval and the expiration time; and

generating a refill indication based on the refill interval.