Functional near-infrared spectroscopy as a monitor for depth of anesthesia
First Claim
1. A method comprising:
- receiving a near-infrared signal in response to directing wavelengths of light in a near-infrared range on a patient;
determining, from the near-infrared signal, a relative deoxyhemoglobin concentration and oxyhemoglobin concentration;
analyzing the percentage of the deoxyhemoglobin concentration to determine a corresponding state of anesthesia; and
administering an amount of anesthetic according to the corresponding state of anesthesia.
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Accused Products
Abstract
Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to obtain a change in deoxyhemoglobin (deoxy-Hb) concentration and/or a change in an oxyhemoglobin concentration (oxy-Hb). The changes in the deoxy-Hb and/or the oxy-Hb may then be compared to determine a state of anesthesia.
The effect of artifacts (e.g., strong surgery room lighting, patient-table tilting, patient intubation/extubation) on the fNIR signal may be removed using a noise removal algorithm. In selecting the noise removal algorithm, a switching technique may be used to select the component analysis algorithm, such as a principal component analysis (PCA), an independent component analysis (ICA), or the like.
11 Citations
48 Claims
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1. A method comprising:
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receiving a near-infrared signal in response to directing wavelengths of light in a near-infrared range on a patient; determining, from the near-infrared signal, a relative deoxyhemoglobin concentration and oxyhemoglobin concentration; analyzing the percentage of the deoxyhemoglobin concentration to determine a corresponding state of anesthesia; and administering an amount of anesthetic according to the corresponding state of anesthesia. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35)
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36. A near-infrared device for determining a state of anesthesia, the device comprising:
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a light detector for receiving a near-infrared signal indicative of a change in light in response to directing wavelengths of light on a patient; and a processor for determining, from the near-infrared signal, a relative deoxyhemoglobin concentration and oxyhemoglobin concentration, and analyzing the percentage of the deoxyhemoglobin concentration to determine a corresponding state of anesthesia. - View Dependent Claims (37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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Specification