Medicament delivery assembly

• US 8,800,550 B2
• Filed: 11/26/2008
• Issued: 08/12/2014
• Est. Priority Date: 11/23/2001
• Status: Expired due to Fees

• Current Assignee: Innovata Biomed Limited (Vectura Group Ltd.)
• Original Assignee: Innovata Biomed Limited (Vectura Group Ltd.)
• Inventors: Braithwaite, Philip
• Primary Examiner(s): DOUGLAS, STEVEN O
• Application Number:
  US12/324,330
• Publication Number:
  US 20090145432A1
• Time in Patent Office: 2,085 Days
• Field of Search: 128/200.21, 128/200.22, 128/203.12, 128/203.15, 128/203.21, 128/200.12
• US Class Current: 128/200.21
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 15/0021 Mouthpieces therefor
• CPC Class Codes: A61M 16/127 by Venturi effect, i.e. entrainment mixers
• CPC Class Codes: A61M 16/206 Capsule valves, e.g. mushroom, membrane valves
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 2205/8218 Gas operated
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

The disclosure relates to a medicament delivery assembly that has a mouthpiece provided with an air amplifier and a primer source, where the mouthpiece and the air amplifier are each connected to the primer source via an actuatable valve. The air amplifier is also provided with a medicament extraction tube such that when the actuatable valve is opened, the primer source is activated and causes air to flow to the air amplifier. There is also described a method of administering a medicament using such a medicament delivery assembly.

Claims

1. A medicament delivery assembly comprising a medicament container and a pulse valve, wherein the assembly is adapted to direct a pulsed gas flow, by means of the pulse valve releasing a gas in a plurality of short, rapid pulses, into the medicament container on a single actuation of the assembly.

2. A medicament delivery assembly as claimed in claim 1, wherein the pulse valve has a cycle of between 10 and 100 cycles/second.

3. A medicament delivery assembly as claimed in claim 1, wherein the pulse valve has a cycle of between 25 and 75 cycles/second.

4. A medicament delivery assembly as claimed in claim 1, wherein the pulse valve is connected to a primer source via an actuatable valve, such that when the actuatable valve is opened, the primer source is activated, thereby causing air to flow to the pulse valve.

5. A medicament delivery assembly as claimed in claim 4, wherein the actuatable valve is a diaphragm valve.

6. A medicament delivery assembly as claimed in claim 4, wherein the assembly is adapted such that when the primer source is activated, air also flows to a mouthpiece.

7. A medicament delivery assembly as claimed in claim 1, wherein the medicament delivery assembly comprises a mouthpiece provided with an air amplifier, the air amplifier being provided with a medicament extraction tube for extracting medicament from the medicament container, and the assembly being adapted to direct the pulsed gas flow to both the medicament container and the air amplifier, such that medicament is extracted from the medicament container.

8. A medicament delivery assembly as claimed in claim 7, wherein the medicament extraction tube is linked to the air amplifier such that non-laminar flow of the medicament is created.

9. A medicament delivery assembly as claimed in claim 7, wherein the medicament extraction tube is connected to a medicament chamber which is an annular chamber adapted to provide non-laminar flow of the medicament.

10. A medicament delivery assembly as claimed in claim 1, wherein the medicament is a powder.

11. A medicament delivery assembly as claimed in claim 1, wherein the assembly comprises an inhaler.

12. A medicament delivery assembly as claimed in claim 11, wherein the inhaler is a dry powder inhaler.

13. A medicament delivery assembly as claimed in claim 11, wherein the inhaler is a metered dose inhaler.

14. A method of administering a medicament which comprises the use of a medicament delivery assembly as claimed in claim 1.

15. A method of treatment of a patient with a respiratory disorder, which comprises administering a medicament using a medicament delivery assembly as claimed in claim 1.

16. A method as claimed in claim 15, wherein the method comprises administration of a medicament by inhalation.

17. A method of treatment of a patient with a systemic disorder which comprises the administration of a medicament using a medicament delivery assembly as claimed in claim 1.

18. A method of treating insulin dependent diabetes which comprises administration of an effective amount of insulin using a medicament delivery assembly as claimed in claim 1.