System and method for delivering a left atrial appendage containment device

• US 8,801,746 B1
• Filed: 05/04/2004
• Issued: 08/12/2014
• Est. Priority Date: 05/04/2004
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Kreidler, Marc S., Frazier, Andrew G. C.
• Primary Examiner(s): Dowe, Katherine
• Assistant Examiner(s): MENDOZA, MICHAEL G
• Application Number:
  US10/838,710
• Time in Patent Office: 3,752 Days
• Field of Search: 606/194, 606/200
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61F 2/0108 Both ends closed, i.e. legs gathered at both ends
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0073 Quadric-shaped
• CPC Class Codes: A61F 2230/0084 cubical

Abstract

A device for containing emboli within a left atrial appendage of a patient includes a frame that is expandable from a reduced cross section to an enlarged cross section and a slider assembly. There is provided in accordance with various embodiments of the present invention methods of preventing retention anchors from projecting outside of the native diameter of the frame, thus facilitating recapture of the device.

Claims

1. An embolic containment device, comprising:

an expandable frame that is moveable between a collapsed configuration and an expanded configuration, the expandable frame having a proximal hub and a distal hub;

a plurality of supports each having a jogged portion and a length extending between the proximal hub and the distal hub, the length defining a longitudinal axis of each support when the frame is in the collapsed configuration, wherein the support extends continuously from the proximal hub of the frame to the distal hub of the frame through the jogged portion; and

a plurality of tissue anchors integrally formed and attached to supports, said anchors extending alongside a portion of said supports and having tissue engagement ends extending, when the frame is in the collapsed configuration, outwardly beyond an outer surface of the expandable frame and generally toward the proximal hub;

wherein the supports have an aspect ratio that decreases in said portion alongside said anchors to form a bending region of said supports, and said anchors are attached proximal to a jogged portion along the length of a corresponding support, said jogged portion turning at least partially laterally away from the longitudinal axis of said support when the frame is in the collapsed configuration.

2. The device of claim 1, further including a barrier provided on at least a proximal face of the frame.

3. The device of claim 1, wherein the plurality of tissue anchors includes a proximal anchor, an intermediate anchor, and a distal anchor attached to each of the plurality of supports.

4. The device of claim 1, wherein the frame in the expanded configuration has a generally spherical shape.

5. The device of claim 1, wherein the frame is self-expanding.

6. The embolic containment device of claim 1, wherein the device is configured for containing embolic material with an atrial appendage of a patient.

7. An implantable device, comprising:

an expandable frame that is moveable between a collapsed configuration and an expanded configuration, the expandable frame having a proximal end and a distal end;

a plurality of supports, each of the plurality of supports having a jogged portion and a length that extends at least partially between the proximal end and the distal end of the frame, the length defining a longitudinal axis of each of the plurality of supports when the frame is in the collapsed configuration; and

a plurality of tissue anchors attached to each of the plurality of supports, each tissue anchor of the plurality of tissue anchors having tissue engagement ends, the tissue engagement ends extending outwardly beyond an outer surface of the expandable frame and generally toward the proximal end of the frame when the frame is in the collapsed configuration; and

wherein each of the plurality of supports has at least a first bending region spaced laterally from one of the plurality of tissue anchors and a second bending region spaced distally from the one of the plurality of tissue anchors, said second bending region having an aspect ratio greater than that of the first bending region, and wherein said first and second bending regions have smaller aspect ratios than an aspect ratio of a portion of each of the plurality of supports that extends between said first and second bending regions.

8. The device of claim 7, wherein the plurality of tissue anchors includes a proximal anchor, an intermediate anchor, and a distal anchor.

9. The device of claim 7, wherein the each of the plurality of tissue anchors is integrally formed with the one of the plurality of supports.

10. A defect closure device, comprising:

an expandable frame that is moveable between a collapsed configuration and an expanded configuration sized to fit within the defect, the expandable frame having a proximal hub and a distal hub;

a plurality of supports each having a jogged portion and a length extending between the proximal hub and the distal hub, the length defining a longitudinal axis of each support when the frame is in the collapsed configuration, wherein the supports extend continuously from the proximal hub of the frame to the distal hub of the frame through the jogged portions; and

a plurality of tissue anchors integrally formed and attached to supports, wherein when the expandable frame is in the collapsed configuration, said anchors extend outwardly beyond an outer surface of the expandable frame and alongside a portion of said supports, the anchors having tissue engagement ends;

wherein the supports have an aspect ratio that decreases in said portion alongside said anchors to form a bending region of said supports, and said anchors are attached adjacent to a jogged portion along the length of a corresponding support, said jogged portion turning at least partially laterally away from the longitudinal axis of said support when the frame is in the collapsed configuration.

11. The defect closure device of claim 10, wherein the expandable frame is sized and configured for placement within a septal defect.

12. The defect closure device of claim 10, wherein the expandable frame is sized and configured for placement within a patent foramen ovale.

13. The defect closure device of claim 10, wherein the expandable frame is sized and configured for placement within a patent ductus arteriosus.

14. An implantable device, comprising:

an expandable frame that is moveable between a collapsed configuration and an expanded configuration;

a plurality of supports, each of the plurality of supports having at least one strut with a first aspect ratio and a bending region with a second aspect ratio that is different from the first aspect ratio, each of the plurality of supports having a jogged portion that extends at least partially laterally away from the at least one strut in the collapsed configuration;

a plurality of anchors attached to a respective one of the plurality of supports, the plurality of anchors including an intermediate anchor, a distal anchor, and a proximal anchor, the intermediate anchor positioned between the proximal anchor and the distal anchor on the respective one of the plurality of supports, the intermediate anchor attached to the respective one of the plurality of supports adjacent to the jogged portion.

15. The device of claim 14, wherein a first support of the plurality of supports includes a first plurality of anchors and a second support of the plurality of supports includes a second plurality of anchors.

16. The device of claim 14, wherein every support of the plurality of supports includes a separate plurality of anchors.

17. The device of claim 14, wherein each of the plurality of anchors has a tissue engagement end that extends generally toward a proximal end of the expandable frame when the frame is in the collapsed configuration.

18. The device of claim 14, wherein each of the plurality of anchors is integrally formed with one of the plurality of supports.

19. The device of claim 14, wherein the plurality of supports and the plurality of anchors are cut from a tube.

20. The device of claim 14, wherein the plurality of supports are metallic.

21. The device of claim 14, wherein the frame is self-expanding.

22. The device of claim 14, wherein the frame includes a proximal hub and a distal hub.

23. The device of claim 14, further including a barrier attached to a portion of the expandable frame.

24. The device of claim 14, wherein the frame is sized and configured for placement within a left atrial appendage of a patient.

25. An implantable device, comprising:

an expandable frame that is moveable between a collapsed configuration and an expanded configuration, the expandable frame having a proximal end and a distal end;

a plurality of supports, each of the plurality of supports defining a longitudinal axis in the collapsed configuration of the frame and having a length that extends at least partially between the proximal end and the distal end of the frame, each of the plurality of supports including at least one strut and at least one bending region, the at least one bending region having an aspect ratio that is less than an aspect ratio of the at least one strut; and

a plurality of anchors attached to a respective one of the plurality of supports, the plurality of anchors including an intermediate anchor, a distal anchor, and a proximal anchor, wherein in the collapsed configuration, the intermediate anchor is positioned at least partially alongside the respective one of the plurality of supports, between the proximal and distal anchors, and spaced laterally from the longitudinal axis of the respective one of the plurality of supports.

26. The device of claim 25, wherein the at least one bending region has an aspect ratio in the range of 1:

1 to 2;

1.

27. The device of claim 25, wherein the at least one bending region has an aspect ratio in the range of 1.5:

1.

28. The device of claim 25, wherein each of the plurality of supports includes at least one jogged portion.

29. The device of claim 25, wherein the plurality of anchors are integrally formed with the respective one of the plurality of supports.

30. The device of claim 25, wherein the plurality of supports and the plurality of anchors are cut from a tube.

31. The device of claim 25, wherein the plurality of supports are metallic.

32. The device of claim 25, wherein the frame is self-expanding.

33. The device of claim 25, wherein the frame includes a proximal hub and a distal hub.

34. The device of claim 25, further including a barrier attached to a portion of the expandable frame.

35. The device of claim 25, wherein the frame is sized and configured for placement within a left atrial appendage of a patient.

36. The device of claim 25, wherein a first support of the plurality of supports includes a first plurality of anchors and a second support of the plurality of supports includes a second plurality of anchors.

37. The device of claim 25, wherein every support of the plurality of supports includes a separate plurality of anchors.