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Materials and methods for prevention and treatment of RNA viral diseases

  • US 8,802,647 B2
  • Filed: 09/17/2012
  • Issued: 08/12/2014
  • Est. Priority Date: 04/30/2002
  • Status: Active Grant
First Claim
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1. A method of increasing expression of 2′

  • -5′

    oligoadenylate synthetase in a mammal, said method comprising administering to the mammal a nucleotide sequence encoding a 2′

    -5′

    oligoadenylate synthetase, or at least one enzymatically active fragment thereof, wherein the nucleotide sequence is expressed in the mammal.

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