Guide tube for an implantable device system

• US 8,805,468 B2
• Filed: 06/07/2012
• Issued: 08/12/2014
• Est. Priority Date: 10/17/2007
• Status: Active Grant

• Current Assignee: Neuronexus Technologies Incorporated (NEL Group, Inc.)
• Original Assignee: Neuronexus Technologies Incorporated (NEL Group, Inc.)
• Inventors: Vetter, Rio J.
• Primary Examiner(s): Cohen, Lee S
• Assistant Examiner(s): Cardinal, Erin M
• Application Number:
  US13/491,358
• Publication Number:
  US 20120316417A1
• Time in Patent Office: 796 Days
• Field of Search: 600/372, 600/373, 600/377, 600/378, 600/544, 600/545, 606/129, 606/76, 607116-118
• US Class Current: 600/378
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease

Abstract

An apparatus comprising an electrode subsystem configured to interface to biological tissue, an electronic subsystem electrically coupled to the electrode subsystem by a connector, and a guide tube disposed over at least a portion of the electrode subsystem and the connector. The guide tube includes material to provide stiffness to the electrode subsystem and the connector in an axial direction of the guide tube. The guide tube material is removable from the electrode subsystem and the connector over the electronic subsystem when the electrode subsystem is positioned to interface to the biological tissue and while the electronic subsystem remains electrically coupled to the electrode subsystem.

Claims

1. An implantable system, comprising:

a) an electrode subsystem configured to interface with biological tissue;

b) an electronic subsystem electrically coupled to the electrode subsystem by a connector; and

c) a guide tube disposed over at least a portion of the electrode subsystem and at least a portion of the connector, the guide tube having a length extending in an axial direction and a width extending in a radial direction, wherein the guide tube comprises an anisotropic material that is rigid in the axial direction and expandable in the radial direction;

d) at least one spiral spline removably disposed longitudinally in the guide tube, the at least one spline being rigid in the axial direction and flexible in the radial direction of the guide tube to thereby provide stiffness to the electrode subsystem and to the connector in the axial direction of the guide tube,

e) wherein the guide tube is removable from the electrode subsystem, the connector, and the electronic subsystem with the guide tube remaining cohesive during such removal.

2. The system of claim 1 wherein the guide tube material is flexible.

3. The system of claim 1, wherein the connector includes a flexible ribbon cable.

4. The system of claim 1, wherein the electrode subsystem includes a plurality of electrodes adapted for recording neural activity.

5. The system of claim 4, wherein the electrodes are adapted by shape and size for deep brain. electrophysiological mapping.

6. The system of claim 4, wherein the connector includes a plurality of flexible ribbon cables to electrically couple the electrodes to the electronic subsystem.

7. The system of claim 4, wherein the plurality of electrodes are formed on a thin-film polymer substrate.

8. The system of claim 1, wherein the electronic subsystem is configured for placement in a cranial chamber.

9. The system of claim 1, wherein the connector includes a cable having fluidic channels formed therein.

10. A guide tube to facilitate insertion of an electrode subsystem and a connector into biological, tissue, the guide tube having a length extending in an axial direction and a width extending in a radial direction, the guide tube comprising:

a) an anisotropic guide tube material that is rigid in the axial direction and flexible in the radial direction of the guide tube,

b) at least one spline removably disposed longitudinally in the guide tube, the spline being rigid in the axial direction and flexible in the radial direction of the guide tube,

c) wherein the guide tube material is expandable in the radial direction and remains cohesive in response to a force applied in the radial direction to effect removal of the guide tube from the electrode subsystem and the connector when the electrode subsystem is positioned to interface with the biological tissue.

11. The system of claim 10, wherein the at least one spline is a spiral spline that is disposed in the guide tube, wherein the spiral spline is rigid in the axial direction and flexible in the radial direction of the guide tube.

12. An implantable system, comprising:

a) an electrode subsystem configured to interface with biological tissue;

b) an electronic subsystem electrically coupled to the electrode subsystem by a connector; and

c) a guide tube disposed over at least a portion of the electrode subsystem and at least a portion of the connector, the guide tube having a length extending in an axial direction and a width extending in a radial direction, wherein the guide tube comprises an anisotropic material that is rigid in the axial direction and expandable in the radial direction;

d) at least one spline removably disposed longitudinally in the guide tube, the at least one spline being rigid in the axial direction and flexible in the radial direction of the guide tube to thereby provide stiffness to the electrode subsystem and to the connector in the axial direction of the guide tube,

e) wherein the guide tube is removable from the electrode subsystem, the connector, and the electronic subsystem.

13. A guide tube having a length extending in an axial direction and a width extending in a radial direction, the guide tube comprising:

a) an anisotropic material that is rigid in the axial direction and expandable in the radial direction;

b) at least one spiral spline removably disposed longitudinally in the guide tube, the at least one spline being rigid in the axial direction and flexible in the radial direction of the guide tube to thereby provide stiffness in the axial direction of the guide tube,

c) wherein the guide tube is removable from an implantable subsystem with the guide tube remaining cohesive during such removal.

14. A method comprising:

a) electrically connecting an electrode subsystem to an electronic subsystem using a connector; and

b) disposing a guide tube over at least a portion of the electrode subsystem and the connector, the guide tube having a length extending in an axial direction and a width extending in a radial direction, wherein the guide tube comprises an anisotropic material that is rigid in the axial direction and expandable in the radial direction;

c) at least one longitudinally extending spline disposed in the guide tube, the at least one spline being rigid in the axial direction and flexible in the radial direction of the guide tube to thereby provide stiffness to the electrode subsystem and to the connector in an axial direction of the guide tube,

d) wherein the guide tube material is removable from the electrode subsystem and from the connector over the electronic subsystem with the guide tube remaining cohesive during such removal when the electrode subsystem is positioned to interface with biological tissue and while the electronic subsystem remains electrically coupled to the electrode subsystem.

15. The method of claim 14 wherein the at least one spline disposed longitudinally in the guide tube is removable from the guide tube.

16. The method of claim 14 wherein the at least one spline is a spiral spline that is disposed in the guide tube, wherein the spiral spline is rigid in the axial direction and flexible in the radial direction of the guide tube.

17. The method of claim 14, wherein electrically connecting the electrode subsystem to the electronic subsystem using a connector includes connecting the electrode subsystem to the electronic subsystem using a flexible ribbon cable.