Ischemia detection systems for paced-patients using beat-type dependent baseline datasets

• US 8,805,498 B1
• Filed: 11/24/2009
• Issued: 08/12/2014
• Est. Priority Date: 11/24/2009
• Status: Expired due to Fees

• Current Assignee: Angel Medical Systems, Inc.
• Original Assignee: Angel Medical Systems, Inc.
• Inventors: Fischell, David R., John, Michael Sasha, Keenan, David
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US12/624,515
• Time in Patent Office: 1,722 Days
• Field of Search: 600/508, 600/510, 607/9
• US Class Current: 607/9
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as ventricularly paced beats and supraventricular beats. The processor collects separate reference data for each beat type indicative of the normal values of a cardiac feature associated with these beat types. The processor performs an ischemia test by separately comparing present values of the cardiac feature for each beat type with the reference values for the corresponding beat type.

Claims

1. An implantable device with ischemia detection and heart pacing capability, including:

at least one electrode adapted for implantation in a body;

circuitry coupled to the electrode to sense signals therefrom and to generate corresponding digital signals;

pacemaker circuitry;

a processor configured to;

distinguish between at least two beat types, including ventricularly paced and supraventricular beats;

collect data from the digital signals for the ventricularly paced and the supraventricular beats within a plurality of heart beat segments;

derive a ventricularly paced baseline for use with the ventricularly paced beats and a supraventricular baseline for use with the supraventricular beats, wherein the ventricularly paced baseline and the supraventricular baseline are indicative of a normal value of a heart signal parameter over a period of at least one hour defining a first time interval;

(a) determine whether a current beat during a second time interval is supraventricular or paced, thereby establishing a current beat type;

(b) determine whether the baseline corresponding to the current beat type is valid for the second time interval;

(c) when the corresponding baseline in said first time interval is valid for said second time interval, apply predetermined ischemia criteria based on the corresponding baseline to the current beat;

(d) when the corresponding baseline is invalid for said second time interval, apply ischemia criteria selected from the group of;

collecting a plurality of the current beat type over a predetermined time interval;

apply a time rate of change of a heart rate feature over said predetermined time interval;

or apply the baseline in said first time interval with a correction factor over said second time interval.

2. The device of claim 1 wherein the baselines for the ventricularly paced and the supraventricular beats are collected using a running average of a minimum number of beats collected between the prior 1 hour and the prior 48 hours.

3. The device of claim 2 wherein the minimum number of beats is 100 beats.

4. The device of claim 1 wherein the processor is further configured to apply separate ischemia detection criteria for the ventricularly paced and the supraventricular beats.

5. The device of claim 4 wherein the processor is further configured to identify ischemic events by counting ischemic beats of either type operative when a sufficient number of such beats exist within a specified interval.

6. The device of claim 1 wherein the processor is further configured to identify ischemic events by counting a number of ischemic beats of both ventricularly paced and the supraventricular beats operative when a sufficient number of such beats exist within a specified interval.

7. The device of claim 1 wherein the processor is further configured assess ST shift pertaining to the ischemic criteria for each beat type.

8. The device of claim 7 wherein the processor is further configured to measure an ST segment for a particular beat type in a different manner according to the type of beat.

9. The device of claim 1, wherein the processor is further configured to use the baseline data for each beat type to determine an ischemia threshold for assessing each type of beat.

10. The device of claim 1, wherein the processor is further configured to use the baseline for each beat type to adjust parameters for measuring features for each type of beat.

11. The device of claim 1, wherein the processor is further configured to apply data acceptance criteria for at least one beat type and to reject data that does not meet the data acceptance criteria from being used as baseline data.

12. The device of claim 1, wherein the processor is further configured to operate to sense cardiac data and collect the baseline data for paced-beat baselines when pacing occurs if baseline data is needed even if this pacing occurs during a time when collection of data segments is not normally scheduled to occur.

13. The device of claim 1 wherein the adaptive reference baselines for the ventricularly paced and the supraventricular beats pertain to the same cardiac feature.