Rapid fluid cooling devices and methods for cooling fluids

• US 8,808,241 B2
• Filed: 10/15/2013
• Issued: 08/19/2014
• Est. Priority Date: 02/24/2009
• Status: Expired due to Fees

• Current Assignee: North Carolina State University (University of North Carolina System)
• Original Assignee: North Carolina State University (University of North Carolina System)
• Inventors: DiMeo, Andrew J., Cox, Nathan M., Grove, Steven P., Lee, Samuel, Oltmans, Luke D., Sauer, Kathryn H.
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): CHANDER, DIVA KAKAR
• Application Number:
  US14/054,315
• Publication Number:
  US 20140046257A1
• Time in Patent Office: 308 Days
• Field of Search: 604 87- 89, 604/113
• US Class Current: 604/113
• CPC Class Codes: A61F 2007/0276 with separate compartments connectable by rupturing a wall or membrane
• CPC Class Codes: A61F 7/0085 Devices for generating hot or cold treatment fluids
• CPC Class Codes: A61F 7/106 self-cooling, e.g. using a chemical reaction
• CPC Class Codes: A61M 19/00 Local anaesthesia syringes therefor A61M5/00; Hypothermia A61M5/42 takes precedence; cooling blood in a bypass of the arterial system A61M1/36
• CPC Class Codes: A61M 2202/04 Liquids
• CPC Class Codes: A61M 2205/3606 cooled
• CPC Class Codes: A61M 2205/364 by chemical reaction
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media
• CPC Class Codes: F25D 5/00 Devices using endothermic chemical reactions, e.g. using frigorific mixtures

Abstract

A cooling device includes a target fluid inlet, a target fluid outlet, an inner conduit, and a chamber surrounding the inner conduit. The inner conduit communicates with the target fluid inlet and the target fluid outlet, and provides a flow path for a target fluid to be cooled. The chamber contains a first endothermic reactant and includes a reactant inlet selectively alterable from a closed state to an open state. When the reactant inlet is in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs. When the reactant inlet is in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the inner conduit.

Claims

1. A cooling device comprising:

a target fluid inlet;

a target fluid outlet;

a plurality of inner conduits fluidly communicating with the target fluid inlet and the target fluid outlet, the plurality of inner conduits providing a plurality of respective flow paths for a target fluid to be cooled; and

a chamber surrounding the plurality of inner conduits and containing a first endothermic reactant, the chamber including a reactant inlet selectively alterable from a closed state to an open state, wherein;

in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs; and

in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the target fluid in the plurality of inner conduits.

2. The cooling device of claim 1, wherein the reactant inlet comprises a fitting configured for connection to an external source of the second endothermic reactant.

3. The cooling device of claim 1, wherein the first endothermic reactant comprises an inorganic salt.

4. The cooling device of claim 3, wherein the second endothermic reactant comprises water.

5. The cooling device of claim 1, wherein at least a portion of each inner conduit is helical.

6. The cooling device of claim 1, wherein the reactant inlet comprises a barrier and in the closed state, the barrier divides the chamber into a first region containing the first endothermic reactant, and a second region containing the second endothermic reactant.

7. The cooling device of claim 6, further comprising an actuator configured to open the barrier wherein the reactant inlet is altered to the open state.

8. The cooling device of claim 7, wherein the actuator is configured to puncture the barrier.

9. The cooling device of claim 7, wherein the actuator is configured to move at least a portion of the barrier to create an opening therethrough.

10. An intravenous target fluid delivery system comprising:

an IV target fluid reservoir including an IV target fluid to be cooled;

a cooling device including;

a target fluid inlet fluidly communicating with the IV target fluid reservoir;

a target fluid outlet;

a plurality of inner conduits fluidly communicating with the target fluid inlet and the target fluid outlet, the plurality of inner conduits providing a plurality of respective flow paths for the IV target fluid to be cooled; and

a chamber surrounding the plurality of inner conduits and containing a first endothermic reactant, the chamber including a reactant inlet selectively alterable from a closed state to an open state, wherein in the closed state, the first endothermic reactant is isolated from a second endothermic reactant and no endothermic reaction occurs, and in the open state, the reactant inlet provides a flow path for enabling the second endothermic reactant to come into contact with the first endothermic reactant in the chamber for initiating the endothermic reaction and cooling the IV target fluid in the inner conduit; and

a cooled IV target fluid receiving tube fluidly communicating with the target fluid outlet, wherein the cooled IV target fluid receiving tube is configured for intravenously administering the cooled IV target fluid to a patient.

11. The intravenous target fluid delivery system of claim 10, wherein the IV target fluid comprises saline solution.

12. The intravenous target fluid delivery system of claim 11, wherein the IV target fluid further comprises a therapeutically active drug.

13. The intravenous target fluid delivery system of claim 10, wherein the reactant inlet comprises a fitting configured for connection to an external source of the second endothermic reactant.

14. The intravenous target fluid delivery system of claim 10, wherein the reactant inlet comprises a barrier and in the closed state, the barrier divides the chamber into a first region containing the first endothermic reactant, and a second region containing the second endothermic reactant.

15. The intravenous target fluid delivery system of claim 14, further comprising an actuator configured to open the barrier wherein the reactant inlet is altered to an open state.

16. The intravenous target fluid delivery system of claim 10, wherein the cooled IV target fluid receiving tube includes an IV catheter.