Implantable infusion device with multiple controllable fluid outlets

• US 8,808,243 B2
• Filed: 07/13/2011
• Issued: 08/19/2014
• Est. Priority Date: 05/26/2005
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medallion Therapeutics, Inc.
• Inventors: Lord, Peter C., Das, Stephen D., Gibson, Scott R.
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): GRAY, PHILLIP A
• Application Number:
  US13/182,412
• Publication Number:
  US 20110270233A1
• Time in Patent Office: 1,133 Days
• Field of Search: 604131-133, 604/890.1, 604/891.1, 604/891.2, 604 65- 67
• US Class Current: 604/131
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

An implantable infusion system includes at least two controllable fluid transfer devices that may be used to transfer different fluid flows to the same or different body sites.

Claims

1. An infusion device configured for implantation in a patient'"'"'s body, the infusion device comprising:

a housing;

a pressure source associated with the housing;

a reservoir in the housing including at least first and second reservoir compartments, the first and second reservoir compartments being positioned relative to one another and relative to the pressure source such that the pressure source acts directly on the first reservoir and the first reservoir separates the pressure source from the second reservoir;

a pressure transmissive interior partition between the first and second reservoir compartments configured to equalize pressure within the first and second reservoir compartments;

a first fluid transfer device operably connected to the first reservoir compartment and to a first fluid outlet;

a second fluid transfer device operably connected to the second reservoir compartment and to a second fluid outlet; and

a controller that controls at least one of the first and second fluid transfer devices.

2. The device of claim 1 wherein the pressure source comprises a propellant that produces a consistent positive pressure.

3. The device of claim 1 wherein the pressure source comprises a propellant that produces a consistent negative pressure.

4. The device of claim 1 wherein the pressure source comprises a pressure transmissive outer wall configured to negatively bias the pressure in the compartments relative to the ambient pressure.

5. The device of claim 1 further comprising

a third reservoir compartment;

and

a pressure transmissive interior partition between the second and third reservoir compartments configured to equalize pressure within the second and third reservoir compartments.

6. The device of claim 1, wherein the pressure transmissive interior partition comprises a flexible polymeric membrane.

7. The device of claim 1, wherein the pressure transmissive interior partition has a wavy shape.

8. The device of claim 1, wherein

the first fluid transfer device comprises a pump.

9. The device of claim 1, wherein

the first fluid transfer device comprises a first pump;

and

the second fluid transfer device comprises a second pump.

10. The device of claim 1, wherein

the first fluid transfer device comprises a valve.

11. The device of claim 1, wherein

the first fluid transfer device comprises a first valve;

and

the second fluid transfer device comprises a second valve.

12. The device of claim 1, wherein

the first fluid outlet comprises a first catheter port;

and

the second fluid outlet comprises a second catheter port.

13. The device of claim 12, wherein

the first and second catheter ports are located in spaced relation to one another.

14. The device of claim 1 further comprising:

a first drug in the first reservoir compartment; and

a second drug in the second reservoir compartment.

15. The device of claim 1 wherein

the pressure source comprises a resilient member having an exterior surface that is exposed to ambient pressure and an interior surface;

the resilient member interior surface and the pressure transmissive interior partition define the first reservoir compartment;

the resilient member is self-biased away from the first reservoir compartment with enough force to create a pressure within the first reservoir compartment that is negative with respect to the ambient pressure; and

the second reservoir compartment is completely separated from the resilient member by the pressure transmissive interior partition.

17. The device of claim 1 further comprising

a first fluid passageway that connects the first reservoir compartment to the first fluid transfer device;

and

a second fluid passageway that connects the second reservoir compartment to the second fluid transfer device.

18. The device of claim 1 wherein

wherein the pressure source is the only non-pump pressure source associated with the first and second reservoir compartments.

16. The device of claim wherein

the second reservoir compartment is located within the first reservoir compartment.

19. An infusion device configured for implantation in a patient'"'"'s body, the infusion device comprising:

a housing;

a reservoir in the housing including at least first and second reservoir compartments;

a first pump connected to the first drug reservoir compartment by a first passageway and connected to a first catheter port;

a second pump connected to the second drug reservoir compartment by a second passageway and connected to a second catheter port;

means, located between the first and second drug reservoir compartments, for equalizing pressure within the first and second drug reservoir compartments; and

a controller that controls at least one of the first and second pumps.

20. The device of claim 19, wherein

the first and second catheter ports are located in spaced relation to one another.

21. The device of claim 19 further comprising:

a first drug in the first drug reservoir compartment; and

a second drug in the drug second reservoir compartment.

22. The device of claim 19 wherein

the housing includes a resilient member having an exterior surface that is exposed to ambient pressure and an interior surface;

the resilient member interior surface and the means for equalizing pressure define the first drug reservoir compartment;

the resilient member is self-biased away from the first drug reservoir compartment with enough force to create a pressure within the first drug reservoir compartment that is negative with respect to the ambient pressure; and

the second drug reservoir compartment is completely separated from the resilient member by the means for equalizing pressure.

23. The device of claim 19 wherein

the first drug reservoir compartment is directly exposed to a non-pump source of negative pressure;

and

the second drug reservoir compartment is not directly exposed to a non-pump source of negative pressure.