Drive assembly and medication delivery device

• US 8,808,251 B2
• Filed: 01/19/2010
• Issued: 08/19/2014
• Est. Priority Date: 01/20/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Raab, Steffen, Brggemann, Ulrich
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): CARPENTER, WILLIAM R
• Application Number:
  US13/143,040
• Publication Number:
  US 20120010576A1
• Time in Patent Office: 1,673 Days
• Field of Search: 604207-211, 604/218, 604/224, 604/232, 604/246
• US Class Current: 604/211
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3157 Means providing feedback signals when administration is completed A61M5/20 takes precedence
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

A drive assembly suitable for a medication delivery device comprises a housing, a drive member, a piston rod, a rotation sleeve, a guide member and a biasing member. The rotation sleeve is arranged to be displaced in a distal direction when the drive member is displaced in the distal direction by mechanical interaction of the drive member and the rotation sleeve with the rotation sleeve and the drive member both being guided axially by the at guide member. The biasing member exerts a force on the rotation sleeve acting in the proximal direction, said force being transformed into a rotational movement of the rotation sleeve. The rotational movement of the rotation sleeve being transformed into a rotational movement of the piston rod.

Claims

1. A drive assembly suitable for a medication delivery device, the drive assembly comprising:

a housing having a proximal end and a distal end, an axis running between the proximal end and the distal end;

a drive member being axially displaceable with respect to the housing for delivering a dose of a medication;

a piston rod which is rotatable with respect to the housing;

a rotation sleeve which is rotatable and axially displaceable with respect to the housing;

a guide member having at least one guide track extending axially, the rotation sleeve being arranged to releasably engage the at least one guide track; and

a biasing member, wherein

the rotation sleeve is arranged to be displaced in the distal direction when the drive member is displaced in the distal direction by mechanical interaction of the drive member and the rotation sleeve with the rotation sleeve and the drive member both being guided axially by the at least one guide track as long as the rotation sleeve engages the at least one guide track, and wherein

the biasing member is biased during distal movement of the rotation sleeve, the biased biasing member exerts a force on the rotation sleeve acting in the proximal direction, said force being transformed into a rotational movement of the rotation sleeve with respect to the housing and a proximal movement of the rotation sleeve with respect to the drive member after the rotation sleeve has disengaged the at least one guide track, the rotational movement of the rotation sleeve being transformed into a rotational movement of the piston rod with respect to the housing.

2. The drive assembly according to claim 1, wherein the guide member comprises at least one guide finger, the at least one guide finger limits the at least one guide track in the direction in which the rotation sleeve rotates after the rotation sleeve has disengaged the at least one guide track.

3. The drive assembly according to claim 2, wherein the rotation sleeve comprises at least one sleeve finger, the at least one sleeve finger being axially displaceable in the at least one guide track.

4. The drive assembly according to claim 3, wherein the drive member has at least one drive finger, the at least one drive finger being axially displaceable in the at least one guide track and wherein the at least one drive finger is capable of moving the at least one sleeve finger distally within the at least one guide track.

5. The drive assembly according to claim 4, wherein:

the at least one guide finger comprises a ramp at its distal end,

the at least one drive finger comprises a ramp at its distal end, and wherein

the ramp of the at least one drive finger and the ramp of the at least one guide finger are configured to temporarily form parts of a continuous rotation ramp together, such that the at least one sleeve finger slides along the rotation ramp after the at least one sleeve finger leaves the at least one guide track.

6. The drive assembly according to claim 5, wherein:

the ramp of the at least one drive finger and a ramp of the at least one sleeve finger abut one another during the axial displacement of the rotation sleeve within the guide track,

the at least one guide finger prevents a rotation of the at least one rotation sleeve as long as the at least one sleeve finger is arranged in the at least one guide track,

the rotation sleeve is capable of disengaging the at least one guide track when the ramp of the at least one sleeve finger reaches the distal end of the at least one guide finger,

the rotation sleeve is capable of rotating after having disengaged the at least one guide track with the ramp of the at least one sleeve finger sliding along the ramp of the at least one drive finger.

7. The drive assembly according to claim 2, wherein the rotation sleeve is configured to reengage the at least one guide track after a disengagement of rotation sleeve and the guide track.

8. The drive assembly according to claim 1, wherein during a displacement of the drive member in the proximal direction with respect to the housing, the rotation sleeve and the piston rod rotate.

9. The drive assembly according to claim 1, wherein the rotation sleeve is displaceable with respect to the piston rod in the axial direction.

10. The drive assembly according to claim 1, wherein the piston rod and the rotation sleeve are engaged such that the piston rod follows the rotational movement of the rotation sleeve.

11. The drive assembly according to claim 1, wherein the piston rod and the housing are threadedly engaged.

12. The drive assembly according to claim 1, wherein:

the piston rod comprises a thread, the thread comprising at least one first and one second region, the pitch of the at least one first region is greater than the pitch of the at least one second region,

the housing comprises a piston rod nut which is arranged to be engaged with the at least one first region and the at least one second region, and

the drive assembly is configured such that, when the drive member is moved proximally and the rotation sleeve rotates, the piston rod nut engages the at least one second region.

13. The drive assembly according to claim 1, wherein one end of the biasing member is supported on the housing and the other end on the rotation sleeve.

14. The drive assembly according to claim 1, wherein the biasing member comprises a compression spring.

15. A medication delivery device, comprising:

a drive assembly according to any of claims 1 to 14,

a medication cartridge, the medication cartridge being coupled to the drive assembly so as to dispense the medication.