Adaptive dispensation in a digestive tract

• US 8,808,276 B2
• Filed: 10/23/2007
• Issued: 08/19/2014
• Est. Priority Date: 10/23/2007
• Status: Expired due to Fees

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Boyden, Edward S., Hyde, Roderick A., Ishikawa, Muriel Y., Kare, Jordin T., Langer, Robert, Leuthardt, Eric C., Rivet, Dennis J., Smith, Michael A., Whitmer, Charles, Wood, Lowell L. Jr., Wood, Victoria Y. H.
• Primary Examiner(s): Bosworth, Kami A
• Assistant Examiner(s): HAYMAN, IMANI N
• Application Number:
  US10/536,126
• Publication Number:
  US 20090192449A1
• Time in Patent Office: 2,492 Days
• Field of Search: 604/65, 604/890.1, 604/67, 604/99.02, 604/164.02, 604/208, 604/246, 604/537, 604/30, 604/891.1, 424/9.1, 424/451, 600/118
• US Class Current: 604/890.1
• CPC Class Codes: A61B 5/07 Endoradiosondes
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/42 Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems A61B1/00, A61B5/4857, A61B5/486, A61B5/4866, A61B5/4869 take precedence
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50

Abstract

Systems and methods are described for implementing a bioactive material selection from within a digestive tract and transmitting a wireless signal indicating at least the bioactive material selection from within the digestive tract.

Claims

1. A bioactive material administration system comprising:

means for coupling two or more reservoirs containing one or more bioactive materials available for selection, the means for coupling enabling the two or more reservoirs to remain in a digestive tract for more than one day;

means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract; and

means for transmitting a first wireless signal indicating at least a bioactive material selection from within the digestive tract.

2. The bioactive material administration system of claim 1 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for indicating at least a remaining amount of one or more medicinal substances.

3. The bioactive material administration system of claim 1 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for indicating at least one component containing one or more bioactive materials in the first wireless signal.

4. The bioactive material administration system of claim 1 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for confirming a selected dosage via the first wireless signal.

5. The bioactive material administration system of claim 2 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for receiving a second wireless signal including at least a device identifier as the bioactive material selection.

6. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for configuring a decision module with one or more attributes of a bioactive mixture.

7. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for activating a dispenser comprising at least one bioactive material and at least one other material.

8. The bioactive material administration system of claim 1 in which the means for a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for signaling a decision of which port of a module to open in response to the bioactive material selection.

9. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for dispensing at least an adhesive in response to the bioactive material selection.

10. The bioactive material administration system of claim 1 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for detecting at least one substance indicative of the bioactive material selection.

11. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for dispensing one or more of a hormone or a vasodilator.

12. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for dispensing one or more of a pain reliever or an appetite suppressant.

13. The bioactive material administration system of claim 1 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for generating the bioactive material selection partly based on a substance detection and partly based on a device configuration.

14. The bioactive material administration system of claim 1 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for indicating at least one pH-modifying material in the first wireless signal.

15. The bioactive material administration system of claim 14 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract further comprises:

means for indicating at least a remaining amount of one or more medicinal substances;

means for indicating at least one component containing one or more bioactive materials in the first wireless signal; and

means for confirming a selected dosage via the first wireless signal.

16. The bioactive material administration system of claim 15 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for receiving a second wireless signal including at least a device identifier as the bioactive material selection;

means for configuring a decision module with one or more attributes of a bioactive mixture as the bioactive material selection;

means for activating a dispenser comprising the bioactive mixture; and

means for signaling a decision of which port of a module to open in response to the bioactive material selection.

17. The bioactive material administration system according to claim 14 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for indicating at least a remaining amount of one or more medicinal substances.

18. The bioactive material administration system according to claim 11 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for indicating at least one component containing one or more bioactive materials in the first wireless signal.

19. The bioactive material administration system according to claim 9 in which the means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

means for confirming a selected dosage via the first wireless signal.

20. The bioactive material administration system according to claim 13 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for configuring a decision module with one or more attributes of a bioactive mixture.

21. The bioactive material administration system according to claim 8 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for activating a dispenser comprising at least one bioactive material and at least one other material.

22. The bioactive material administration system according to claim 14 in which the means for implementing a selective dispensation of at least one bioactive material available for selection from the two or more reservoirs from within the digestive tract comprises:

means for signaling a decision of which port of a module to open in response to the bioactive material selection.

33. The bioactive material administration system of claim 1 wherein the means for coupling two or more reservoirs containing one or more bioactive materials available for selection comprises:

means for coupling two or more reservoirs containing one or more bioactive materials available for selection into at least one of a ring form or a tetrahedral form.

23. A bioactive material administration system comprising:

circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day; and

circuitry for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract.

24. The bioactive material administration system of claim 23 in which the circuitry for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract comprises:

circuitry for indicating at least one component containing one or more bioactive materials in the first wireless signal.

25. The bioactive material administration system of claim 23 in which the circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day comprises:

circuitry for receiving a second wireless signal including at least a device identifier as the bioactive material selection.

26. The bioactive material administration system of claim 23 in which the circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day comprises:

circuitry for configuring a decision module with one or more attributes of a bioactive mixture.

27. The bioactive material administration system of claim 23 in which the circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day comprises:

circuitry for signaling a decision of which port of a module to open in response to the bioactive material selection.

28. The bioactive material administration system of claim 23 in which the circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day comprises:

circuitry for dispensing one or more of a hormone or a vasodilator.

29. The bioactive material administration system of claim 23 in which the circuitry for implementing a selective dispensation of at least one bioactive material available for selection from two or more reservoirs containing one or more bioactive materials from within a digestive tract, wherein the two or more reservoirs are configured to remain in the digestive tract for more than a day comprises:

circuitry for dispensing one or more of a pain reliever or an appetite suppressant.

30. The bioactive material administration system of claim 23 further comprising:

a module containing at least some of the circuitry for implementing a bioactive material selection from within a digestive tract.

31. A bioactive material administration system comprising:

means for implementing a bioactive material selection from within a digestive tract;

means for coupling two or more reservoirs containing one or more bioactive materials available for selection into at least one of a ring form or a tetrahedral form, the means for coupling enabling the two or more reservoirs to remain in a digestive tract for more than one day;

means for activating a dispenser comprising at least one bioactive material and at least one other material; and

means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract.

32. A bioactive material administration system comprising:

means for implementing a bioactive material selection from within a digestive tract;

means for coupling two or more reservoirs containing one or more bioactive materials available for selection into at least one of a ring form or a tetrahedral form, the means for coupling enabling the two or more reservoirs to remain in a digestive tract for more than one day;

means for transmitting a first wireless signal indicating at least the bioactive material selection from within the digestive tract;

means for indicating at least one pH-modifying material in the first wireless signal;

means for indicating at least a remaining amount of one or more medicinal substances;

means for indicating at least one component containing one or more bioactive materials in the first wireless signal;

means for confirming a selected dosage via the first wireless signal;

means for receiving a second wireless signal including at least a device identifier as the bioactive material selection;

means for configuring a decision module with one or more attributes of a bioactive mixture as the bioactive material selection;

means for activating a dispenser comprising the bioactive mixture; and

means for signaling a decision of which port of a module to open in response to the bioactive material selection.