Posterior segment drug delivery
First Claim
1. A therapeutic device to treat an eye of a patient, the eye having a sclera, the therapeutic device comprising:
- a rigid-walled, refillable reservoir having a volume and a distal portion, at least the distal portion of the reservoir adapted to reside inside the eye when the device is implanted in the eye, the reservoir having a cross-sectional shape defined along a plane perpendicular to a longitudinal axis of the device;
a cap portion positioned near the reservoir and adapted to be positioned against an external surface of the sclera when the device is implanted in the eye, the cap portion including at least a portion of a penetrable barrier to introduce the therapeutic agent into the device without any need to explant the device during introduction of the therapeutic agent into the device; and
a neck portion adjacent the cap portion, the neck having a cross-sectional shape defined along a plane perpendicular to a longitudinal axis of the device,wherein the cross-sectional shapes of the neck portion and the reservoir portions are each defined at their widest locations by a long width, and wherein the reservoir portion has a long width sized larger than the long width of the neck portion.
2 Assignments
0 Petitions
Accused Products
Abstract
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
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Citations
7 Claims
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1. A therapeutic device to treat an eye of a patient, the eye having a sclera, the therapeutic device comprising:
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a rigid-walled, refillable reservoir having a volume and a distal portion, at least the distal portion of the reservoir adapted to reside inside the eye when the device is implanted in the eye, the reservoir having a cross-sectional shape defined along a plane perpendicular to a longitudinal axis of the device; a cap portion positioned near the reservoir and adapted to be positioned against an external surface of the sclera when the device is implanted in the eye, the cap portion including at least a portion of a penetrable barrier to introduce the therapeutic agent into the device without any need to explant the device during introduction of the therapeutic agent into the device; and a neck portion adjacent the cap portion, the neck having a cross-sectional shape defined along a plane perpendicular to a longitudinal axis of the device, wherein the cross-sectional shapes of the neck portion and the reservoir portions are each defined at their widest locations by a long width, and wherein the reservoir portion has a long width sized larger than the long width of the neck portion. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification