Please download the dossier by clicking on the dossier button x
×

Optimized Fc variants and methods for their generation

  • US 8,809,503 B2
  • Filed: 05/20/2013
  • Issued: 08/19/2014
  • Est. Priority Date: 09/27/2002
  • Status: Expired due to Term
First Claim
Patent Images

1. A variant Fc region of a human parent IgG1 Fc region, wherein said variant Fc region comprises an amino acid substitution in the human parent Fc region at position 264, wherein said variant Fc region exhibits altered binding affinity to an Fcγ

  • receptor (Fcγ

    R) as compared to a parent Fc region and wherein numbering is according to the EU index.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×